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Presenter Disclosure Information In compliance with the accrediting board policies, the American Diabetes Association requires the following disclosure.

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Presentation on theme: "Presenter Disclosure Information In compliance with the accrediting board policies, the American Diabetes Association requires the following disclosure."— Presentation transcript:

1 Presenter Disclosure Information In compliance with the accrediting board policies, the American Diabetes Association requires the following disclosure to the participants: NAME OF PRESENTER: Curtis Triplitt, PharmD, CDE Speaker’s Bureau: Amylin, Eli Lilly, Novartis, Takeda Board Member/Advisory Panel: Amylin, Eli Lilly

2 Treating Type 2 DM in the 21 st Century Curtis Triplitt, PharmD, CDE Texas Diabetes Institute Asst. Professor, Dept. of Medicine/ Div. of Diabetes Clinical Assistant Professor of Pharmacy University of Texas Health Science Center San Antonio, Texas

3 Presentation not available due to pending publication and intellectual property issues.

4 The following references were used: Pathophysiologic Basis of Treatment: Adapted from Inzucchi SE. JAMA. 2002;287: Factors that Influence the Efficiency of Inhaled Insulin: Nature Reviews Drug Discovery 1; (2002) Exubera Inhaled Insulin Change-Baseline FEV1 in T1DM: September 8, 2005, EMDAC Meeting, Food and Drug Administration Exubera Inhaled Insulin Change-Baseline DLCO in Type 1 DM - Pooled Phase 2 and 3 Studies: September 8, 2005, EMDAC Meeting, Food and Drug Administration Technosphere/MannKind Insulin monomer human [rDNA origin]) Inhalation Powder and the AFRESA (R) Inhaler: Diabetes Technology and Therapeutics 2002;4(5):589 Technosphere/MannKind Inhaled Insulin: Rosenstock J.et al. ADA Scientific Sessions. 2005, San Diego, CA: 357-OR When Does Beta-Cell Function Decline? Ferrannini, E. et al. J Clin Endocrinol Metab 2005;90: Initial Combination Therapy With Sitagliptin Plus Metformin Study: Design-Data available on request from Merck & Co., Inc. Please specify (1)-JAN. Initial Combination Therapy With Sitagliptin Plus Metformin Study: A1C Results Through 104 Wks (2 years): 1. Goldstein BJ et al. Diabetes Care. 2007;30(8):1979– Data available on request from Merck & Co., Inc. Please specify (1)-JAN. Study Results: Placebo-subtracted HbA 1c Reductions in Combination Therapy Studies- Williams-Herman D, et al. Abstract 875. Presented at the 19th World Diabetes Congress, 3–7 December 2006, Cape Town, South Africa. Liraglutide’s Impact on Glucagon Secretion inType 2 Diabetes Mellitus- Degn KB, et al. Diabetes 2004, 53: Exenatide BID versus Exenatide QW- Drucker D, Buse JB, Taylor K et al. DURATION-1 trial online Lancet Sept DOI: /S (08) A1C: 52-Week Evaluable Population-A1C: 52-Week Evaluable Population- Buse J et al. Extenatide once weekly elicits sustained glycemic controls and weight loss over 52 weeks. Presented at: the 68th Annual Meeting of the American Diabetes Association; June 6-10, 2008; San Francisco,CA. FPG: 52-Week Evaluable Population-FPG: 52-Week Evaluable Population- Buse J et al. Extenatide once weekly elicits sustained glycemic controls and weight loss over 52 weeks. Presented at: the 68th Annual Meeting of the American Diabetes Association; June 6-10, 2008; San Francisco, CA. Weight Loss Through Week 52-Weight Loss Through Week 52-Buse J et al. Extenatide once weekly elicits sustained glycemic controls and weight loss over 52 weeks. Presented at: the 68th Annual Meeting of the American Diabetes Association; June 6-10, 2008; San Francisco, CA. Type 2 DM: Pancreatitis-1. Frey et al. Pancreas (4): Martinez et al. Pancreatology 2006;6: Liraglutide and Calcitonin-http://www.fda.gov/ohrms/dockets/ac/09/briefing/ b2-01-FDA.pdf Thiazolidinediones- Nature Medicine 2005;11: Limb Fractures in Women with Rosiglitazone- J of Endocrinology 2004;183:203-16; Nature Medicine 2007;13:


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