Presentation on theme: "Roundworms Pathophysiology. Ascaris lumbricoides largest nematode parasitizing the human intestine most common human helminthic infection worldwide."— Presentation transcript:
Ascaris lumbricoides largest nematode parasitizing the human intestine most common human helminthic infection worldwide
MOT: ingestion of infective eggs Larval migration through the lungs Most common site: JEJUNUM
Case Ascaris Bolus
Ascariasis Diagnosis: identification of eggs in the stool
ASCARIASIS DOC:mebendazole blocks glucose uptake of the parasite
Enterobiaisis Enterobius vermicularis human pinworm Adult females: 8 to 13 mm, adult male: 2 to 5 mm Humans : only hosts
MOT: ingestion of eggs
Enterobiasis most typical symptom nocturnal perianal pruritus Ectopic enterobiasis
Enterobiasis Diagnosis: microscopic identification of eggs Scotch test cellulose-tape slide test (3 negative results) Swube tubes
Pinworm Collector Tubes
Flashlight test: “cotton threads”
Enterobiasis DOC: pyrantel pamoate. -spastic paralysis of the worm
Trichinellosis (trichinosis) Trichinella spiralis Worldwide Most common in parts of Europe and the United States
MOT: ingestion of contaminated meat with encysted cyst
The nurse cell–Larvae complex may persist for 6 months to several years before calcification and death occur.
trichinellosis (trichinosis), Steroids Albendazole: decreases ATP production in worms, causing energy depletion, immobilization, and death
Prevention adequate cooking to kill the parasite. If no trace of pink in fluid or flesh is found, these temperatures have been reached.
Freezing : Salting, smoking, or drying the meat does not kill cysts.
Human hookworms Ancylostoma duodenale: Old World hookworm Necator americanus: New World hookworm Ancylostoma braziliense: penetrate the human skin (causing cutaneous larva migrans), but do not develop any further
HOOKWORMS second most common human helminthic infection Worldwide distribution, mostly in areas with moist, warm climate
MOT: skin penetration by filariform larvae Veins heart lungs trachea GIT oral and transmammary route
HOOKWORMS Necator ingests 0.03 mL of blood per worm per day Ancylostoma ingests 0.20 mL blood per worm per day.
HOOKWORMS Ground itch: Necator -intensely pruritic, erythematous, or vesicular rash usually appears on the feet or hands pneumonitis (Loefflerlike syndrome) manifested by cough, fever, and malaise.
HOOKWORMS DIAGNOSIS: Microscopic identification of eggs in the stool AncylostomaNecator
HOOKWORM DOC: Albendazole, Mebendazole or pyrantel pamoate can also be used
Ancylostoma braziliensis (cutaneous larva migrans, creeping eruption) tropical and subtropical countries Gulf and southern Atlantic states. primarily a hookworm of dogs and cats can infect man and cause skin eruptions larvae have a tendency to move around for 2 to 10 weeks