What type of hormones are produced? ADH (antidiuretic hormone) Oxytocin
How do these hormones affect the body? ADH- Promotes reabsorption of water by the kidneys Oxytocin- strongly affects human social interactions, stimulates uterine contractions during childbirth and facilitates breast feeding AKA the “love hormone”
Maintenance of homeostasis ADH- helps maintain water and electrolyte balance The pituitary and the hypothalamus glands work together to regulate the release of other hormones in the body.
Feedback Mechanisms ADH- when there is not enough water in the blood ADH is secreted so the kidneys reabsorb water (negative feedback) Oxytocin- during childbirth, oxytocin is released to stimulate uterine contraction and lactation from the mammary glands (positive feedback)
Antagonistic Hormones Vasopressin Receptor Antagonist (VRA)- blocks ADH for those with congestive heart failure Atosiban (oxytocin receptor antagonist)- blocks Oxytocin to control emotions and hormones
Disorders With a damaged or malfunctioning pituitary gland, your body would lose the normal ability to regulate the hormones released by most endocrine glands. Disorders of the posterior pituitary gland are: diabetes insipidus Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)
Diabetes insipidus Condition where the kidneys are unable to conserve water due to lack of ADH Symptoms- Extreme thirst Excessive urine volume Treatment- Medication (vasopressin)
SIADH Condition where high levels of ADH cause the kidneys to absorb excessive amounts of water. Symptoms- Nausea/vomiting Cramping Seizures Coma Treatment- Surgery to remove the gland releasing ADH Medication to block ADH