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Capillaria philippinensis Created and Presented by: Lindsey Petrovich Amanda Reinesch.

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Presentation on theme: "Capillaria philippinensis Created and Presented by: Lindsey Petrovich Amanda Reinesch."— Presentation transcript:

1 Capillaria philippinensis Created and Presented by: Lindsey Petrovich Amanda Reinesch

2 TAXONOMY KINGDOM : Animalia KINGDOM : Animalia PHYLUM : Nematoda PHYLUM : Nematoda CLASS : Aphasmidea CLASS : Aphasmidea ORDER : Anoplida ORDER : Anoplida FAMILY : Capillariidae – Capillaria FAMILY : Capillariidae – Capillaria Roundworm Nematode Roundworm Nematode Intestinal Parasite Intestinal Parasite

3 GEOGRAPHIC DISTRIBUTION * Philippines * Thailand Rare cases have been reported from other Asian countries, Iran, Middle East, Japan, Egypt and Colombia. Rare cases have been reported from other Asian countries, Iran, Middle East, Japan, Egypt and Colombia.

4 Interesting Facts First discovered in 1963 in Northern Luzon, Philippines First discovered in 1963 in Northern Luzon, Philippines Appearance in humans was sudden and unexpected Appearance in humans was sudden and unexpected Witch Doctors hired to drive out curse placed on people by River God Witch Doctors hired to drive out curse placed on people by River God

5 MORPHOLOGY - Adult Male -2.3-3.2 mm long -23-28 μm wide -Small caudal alae -Spineless spicule sheath - Adult Female -2.5-4.3 mm long -29-47 μm wide -Esophagus is half as long as body -Produce Capillaria -type eggs that lack pits - Egg -36-45 μm long -20 μm wide -Peanut shaped -Striated shell

6 LIFE CYCLE DEFINITIVE HOST: DEFINITIVE HOST: fish-eating birds fish-eating birds INTERMEDIATE HOST : INTERMEDIATE HOST : Fish Fish VECTOR: VECTOR: None None ACCIDENTAL HOSTS: ACCIDENTAL HOSTS: Human Human Acquire by eating small species of raw infected fish Acquire by eating small species of raw infected fish Direct and Indirect Life Cycles Direct and Indirect Life Cycles

7 LIFE CYCLE 1.Unembryonated eggs are passed in human/bird stool. 2.Unembryonated eggs become embryonated in the external environment. 3.Fresh water fish ingest embryonated eggs, larvae hatch, penetrate the intestine, migrate to tissues. 4.Ingestion of raw or undercooked fish results in infection of human host. 5.Adult worms reside in human small intestine, burrow in mucosa. 6.Female adult worms deposit unembryonated eggs. - Some eggs become embryonated in intestine, release larvae, cause autoinfection, leading to hyperinfection 7.Parasite of fish-eating birds. - (Birds eat small fish)

8 PATHOGENESIS In Humans Causes intestinal capillariasis Causes intestinal capillariasis Damages cells of intestinal wall Damages cells of intestinal wall Worms repeatedly penetrate mucosa of small intestine and reenter lumen (jejunum) Worms repeatedly penetrate mucosa of small intestine and reenter lumen (jejunum) Leads to progressive degeneration of mucosa and submucosa Leads to progressive degeneration of mucosa and submucosa Interferes with absorption of nutrients (fats and sugars) and maintenance of proper electrolyte (potassium) balance Interferes with absorption of nutrients (fats and sugars) and maintenance of proper electrolyte (potassium) balance

9 PATHOGENESIS In Humans SYMPTOMS: Watery diarrhea Abdominal pain Edema Weight loss Weakness Malaise Anorexia Emaciation Borborygmus (stomach growling) Depressed levels of potassium and albumin in blood

10 DIAGNOSIS In Humans Finding eggs, larvae, and/or adults in : Finding eggs, larvae, and/or adults in : Stool samples Stool samples Unembryonated eggs Unembryonated eggs Severe infections have eggs, larvae, and adults Severe infections have eggs, larvae, and adults Intestinal biopsies Intestinal biopsies Often fatal if left untreated Often fatal if left untreated Patients die from: Patients die from: Loss of electrolytes Loss of electrolytes Heart Failure Heart Failure Secondary Bacterial Infections Secondary Bacterial Infections

11 TREATMENT In Humans Anthelmintics - Mebendazole - Albendazole - Thiabendazole

12 CONTROL For Humans Avoid eating small raw fish whole Education

13 REFERENCES: http://en.wikipedia.org/wiki/Capillaria_philippinensis http://en.wikipedia.org/wiki/Capillaria_philippinensis http://en.wikipedia.org/wiki/Capillaria_philippinensis http://medinfo.psu.ac.th/pr/MedBoard/Img/20080605080200.jpg http://medinfo.psu.ac.th/pr/MedBoard/Img/20080605080200.jpg http://medinfo.psu.ac.th/pr/MedBoard/Img/20080605080200.jpg http://www.dpd.cdc.gov/dpdx/HTML/Frames/A-F/Capillariasis/body_Capillariasis_page2.htm http://www.dpd.cdc.gov/dpdx/HTML/Frames/A-F/Capillariasis/body_Capillariasis_page2.htm http://www.dpd.cdc.gov/dpdx/HTML/Frames/A-F/Capillariasis/body_Capillariasis_page2.htm http://www.dpd.cdc.gov/dpdx/HTML/Frames/A-F/Capillariasis/body_Capillariasis_mic1.htm http://www.dpd.cdc.gov/dpdx/HTML/Frames/A-F/Capillariasis/body_Capillariasis_mic1.htm http://www.dpd.cdc.gov/dpdx/HTML/Frames/A-F/Capillariasis/body_Capillariasis_mic1.htm http://www.dpd.cdc.gov/dpdx/HTML/Frames/A- F/Capillariasis/body_Capillariasis_page1.htm#Geographic%20Distribution http://www.dpd.cdc.gov/dpdx/HTML/Frames/A- F/Capillariasis/body_Capillariasis_page1.htm#Geographic%20Distribution http://www.dpd.cdc.gov/dpdx/HTML/Frames/A- F/Capillariasis/body_Capillariasis_page1.htm#Geographic%20Distribution http://www.dpd.cdc.gov/dpdx/HTML/Frames/A- F/Capillariasis/body_Capillariasis_page1.htm#Geographic%20Distribution http://upload.wikimedia.org/wikipedia/commons/b/be/Ph_locator_map_luzon.png http://upload.wikimedia.org/wikipedia/commons/b/be/Ph_locator_map_luzon.png http://upload.wikimedia.org/wikipedia/commons/b/be/Ph_locator_map_luzon.png http://www.stanford.edu/class/humbio103/ParaSites2005/Capillariasis/capillaria%20images/bird.JPG http://www.stanford.edu/class/humbio103/ParaSites2005/Capillariasis/capillaria%20images/bird.JPG http://www.stanford.edu/class/humbio103/ParaSites2005/Capillariasis/capillaria%20images/bird.JPG http://www.stanford.edu/class/humbio103/ParaSites2006/Enterobius/Mebendazole%20Tablets%20USP%20 100mg%20100mg.jpg http://www.stanford.edu/class/humbio103/ParaSites2006/Enterobius/Mebendazole%20Tablets%20USP%20 100mg%20100mg.jpg http://www.stanford.edu/class/humbio103/ParaSites2006/Enterobius/Mebendazole%20Tablets%20USP%20 100mg%20100mg.jpg http://www.stanford.edu/class/humbio103/ParaSites2006/Enterobius/Mebendazole%20Tablets%20USP%20 100mg%20100mg.jpg http://www.richygold.com/my_images/albendzole.jpg http://www.richygold.com/my_images/albendzole.jpg http://www.richygold.com/my_images/albendzole.jpg http://curezone.com/upload/Blogs/Zoebess/raw_fish.jpg http://curezone.com/upload/Blogs/Zoebess/raw_fish.jpg http://curezone.com/upload/Blogs/Zoebess/raw_fish.jpg http://www.encognitive.com/images/digestive-system-2.jpg http://www.encognitive.com/images/digestive-system-2.jpg http://www.encognitive.com/images/digestive-system-2.jpg


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