Recognition & Attachment Opsoninzation Opsonins –Fc fragment of IgG –C3b –Mannose-binding protein (produced in the liver) Covers the surface of microorganisms and is recognized by neutrophils and macrophages
Activation and Destruction (killing) Oxygen dependent killing –myeloperoxidase requires hydrogen peroxide and halide (e.g., Cl - ) to produce HOCl –Hydrogen peroxide and ferrous ion without myeloperoxidase will generate OH free radical
Noninflammatory and Inflammatory Conditions Transudate - fluid with low protein content and a specific gravity <1.012 Exudate - inflammatory extracellular fluid composed of plasma proteins, principally albumin, cells and cellular debris, and a specific gravity >1.020
Noninflammatory and Inflammatory Conditions Anasarca - edema which is severe and generalized Abscess - localized collections of pus caused by suppuration buried in a tissue, organ, or confined space Cellulitis - spreading suppurations in subcutaneous tissue
Your consent to our cookies if you continue to use this website.