Presentation on theme: "UPDATE IN HIGH ALTITUDE MEDICINE Scott McKee MD MPH Rocky Mountain GIM: Banff 2012 UPDATE IN HIGH ALTITUDE MEDICINE Scott McKee MD MPH Rocky Mountain –"— Presentation transcript:
UPDATE IN HIGH ALTITUDE MEDICINE Scott McKee MD MPH Rocky Mountain GIM: Banff 2012 UPDATE IN HIGH ALTITUDE MEDICINE Scott McKee MD MPH Rocky Mountain – ACP Banff 2012 Practice guidelines New technologies Drug therapy
Lots of free gear from outdoor product retailers, but none since 1997 DISCLOSURES: Lots of free gear from outdoor product retailers – but none since 1997!
You will be called upon to diagnose and treat in the field…
Why do GIMs care? You will be called upon to diagnose and treat in the hospital, and in the ICU…
Why does it matter? You will be called to give advice to potential patients of all levels of health and fitness, including those with pre- existing conditions…
Demographics: -Climbers/skiers -Tourists to mountain resorts -Miners/Operations -Soldiers -Performance Athletes -Pilots/balloonists Comorbidities: -CVD: all varieties -COPD/CF/OSA -Anemias -VTE/anticoagulation -Migraine/CVD/epilepsy -Pregnancy/pediatrics -Diabetes -Transplant patients & immunosuppression -Retinal/corneal surgeries -Drug therapy & interactions Research Funding: -Aviation/Aerospace -Military -Wilderness Medicine -Tourism Bureaus -Sports Medicine
REVIEW ARTICLE Wilderness Medical Society Consensus Guidelines for the Prevention and Treatment of Acute Altitude Illness Andrew M. Luks, MD; Scott E. McIntosh, MD, MPH; Colin K. Grissom, MD; Paul S. Auerbach, MD, MS; George W. Rodway, PhD, APRN; Robert B. Schoene, MD; Ken Zafren, MD; Peter H. Hackett, MD WILDERNESS & ENVIRONMENTAL MEDICINE, 21, 146–155 (2010)
To provide guidance to clinicians about best practices, the Wilderness Medical Society (WMS) convened an expert panel to develop evidence- based guidelines for the prevention and treatment of acute mountain sickness (AMS), high altitude cerebral edema (HACE), and high altitude pulmonary edema (HAPE). These guidelines present the main prophylactic and therapeutic modalities for each disorder and provide recommendations for their roles in disease management. The guidelines also provide suggested approaches to the prevention and management of each disorder that incorporate these recommendations.
Into thin air: extreme ultrasound on Mt Everest. Otto C, Hamilton DR, Levine BD, Hare C, Sargsyan AE, Altshuler P, Dulchavsky SA. Department of Emergency Medicine, University of Ottawa, Ottawa, Canada. Wilderness Environ Med Fall;20(3):283-9.
Crit Care Med.Crit Care Med Sep;38(9): Frequent subclinical high-altitude pulmonary edema detected by chest sonography as ultrasound lung comets in recreational climbers. Institute of Clinical Physiology, CNR, Pisa, Italy. CONCLUSIONS: In recreational climbers, chest sonography revealed a high prevalence of clinically silent interstitial pulmonary edema mirrored by decreased O(2) saturation, whereas no statistically significant relationship with pulmonary artery systolic pressure was observed during ascent.
Stroke at High Altitude Diagnosed in the Field Using Portable Ultrasound Wilderness & Environmental Medicine Volume 22, Issue 1, Pages 54-57, March 2011 Volume 22, Issue 1
-PDE 5 inhibitors: small studies, wide usage, considerable anecdotal support, for HAPE prevention and treatment. -Ibuprofen: 2 randomized controlled trials : ASCENT (ibu vs placebo) 2012 and HEAT (ibu vs acetazolamide) Seems to be equivalent for AMS prevention…
HIGH ALTITUDE MEDICINE & BIOLOGY Volume 11, Number 1, 2010 Caffeine at High Altitude: Java at Base Camp Peter H. Hackett MD
“In summary, contrary to conventional wisdom, caffeine use at high altitude seems to be not only safe but likely beneficial…” “Importantly, habitual caffeine users should not discontinue caffeine because of travel to altitude; the symptoms of withdrawal are very similar to acute mountain sickness and can be misdiagnosed as AMS.”
Altitude Research Center at University of Colorado Denver School of Medicine Wilderness Medical Society International Society for Mountain Medicine International Hypoxia Symposia Himalayan Rescue Association American College of Emergency Physicians - Wilderness Medicine Section Wilderness Medicine - Stanford University School of Medicine Everest ER Keystone Symposia
18th International Hypoxia Symposium 26 February to 2 March 2013 Chateau Lake Louise (www.hypoxia.net)
Wednesday -Recent Developments Involving Hypoxia Inducible Factor in Clinical Medicine -The Exercising Hypoxic Brain: N Prabakhar, L Shimoda, G Semenza Thursday Genomics, Population Genetics and Metabolism: P Robbins, J Prchal, D McClain New Advances in Hemoglobin Biology: Peter Wagner, Mark Gladwin Friday Cerebral Blood Flow In Hypoxia: From Early Human Experiments to Systems Biology Debate: Is Live-High Train-Low (LHTL) Effective for Improving Sea Level Athletic Performance? —LHTL is NOT Effective for Sea Level Performance Enhancement—Carsten Lundby — LHTL IS Effective for Sea Level Performance Enhancement —Ben Levine Evening Everest Long Ago—Tom Hornbein Saturday Nitrite, Nitrate, and Oxygen Delivery in Hypoxia Also Steve Herrero and Bernadette McDonald
“In summary, contrary to conventional wisdom, caffeine use at high altitude seems to be not only safe but likely beneficial…” Importantly, habitual caffeine users should not discontinue caffeine because of travel to altitude; the symptoms of withdrawal are very similar to acute mountain sickness and can be misdiagnosed as AMS.