Management of BRVO (BVOS) Wait for haemorrhage to clear (3 months). FFA : Macular edema and VA 6/12 or worse after 3 months –grid laser & follow-up after 2-3 months. Macular ischemia—no treatment. 5 DD or > area of CNP– 4 monthly follow- up for 12-24 months. Neovascularisation– scatter laser
CRVO Ischemic Non-ischemic Frequency 25% 75% VA 20/400 or < (90%)> than 20/400 (90%) Site at lamina cribrosaFar behind lam crib RAPD markedslight VF defect commonrare FundusExt hgs & cotton wool spots, severe disc edema, marked tortuosity of vessels Less exten hgs, few cotton wool spots, mild disc edema, variable tortuosity of vessels
CRVO Ischemic Non-ischemic FFAWide spread capillary non- perfusion Delayed venous return, late leakage, good perfusion. ERGReduced “b” wave amplitude, reduced “b/a” ratio normal Prognosis50% develop rubeosis & NVG in 2-4 months 3% develop rubeosis and NVG. 50% return to VA 6/12 or better.
Non-ischemic CRVO ( Course and Follow-up) Residual signs: Disc collaterals, epiretinal gliosis, pigmentary changes at macula. Conversion to ischemic CRVO occurs in 15% of cases within 4 months and 34% within 3 years. Follow-up: should be for 3 years. Prognosis: depends on initial VA, near normal VA in 50%, Chronic CMO- unresponsive to laser (CVOS). 8-10% risk of BRVO or CRVO in the fellow eye.
Ischemic CRVO: Management (CVOS) Follow-up: monthly for 6 months IOP, undilated gonioscopy & SLE Angle NV is the best clinical predictor of NVG. Treatment: PRP in eyes with angle or iris NV. Monthly follow-up until stabilisation or regression.
Hemiretinal vein occlusion Less common than BRVO and CRVO Occlusion of superior or inferior branch of the CRV. Features of BRVO, involving the superior or inferior hemisphere Prognosis depends on severity of macular edema and ischemia.
PAPILLOPHLEBITIS (Optic disc vasculitis) Healthy individuals, < 50 years Optic disc swelling with secondary venous congestion rather than venous thrombosis. APD absent, retinal haemorrhages confined to posterior fundus. Prognosis: 80% -- 6/12 or better 20% visual loss -- macular edema
Management:Recent advances Recent onset of non-ischemic CRVO– high intensity laser to create chorioretinal shunt. AV sheathotomy for treatment of CME due to BRVO. Ischemic CRVO:- PP Vitrectomy + Intraocular gas + Radial neurotomy
Management: Recent advances Intravitreal tPA Transvitreal vein cannulation Section of posterior scleral ring Drug therapy -- Troxerutin -- Petroxyfylline -- Hemodilution Intravitreal Triamcinolone