1. Welcome to the CLU-IN Internet Seminar Superfund Research Program P42 RFA Briefing (RFA ES 14-007 – rerelease of RFA ES 14-001) Sponsored by: National Institute of Environmental Health Sciences, Superfund Research Program Presenters: William A. Suk, Director, Superfund Research Program (SRP), NIEHS (suk@niehs.nih.gov)suk@niehs.nih.gov Heather Henry, Program Administrator, SRP NIEHS (henryh@niehs.nih.gov)henryh@niehs.nih.gov Danielle Carlin, Program Administrator, SRP NIEHS (danielle.carlin@nih.gov)danielle.carlin@nih.gov Lisa Edwards, Grants Management Specialist, NIEHS (archer3@niehs.nih.gov)archer3@niehs.nih.gov Michelle Victalino, Grants Management Specialist, NIEHS (victalinom@niehs.nih.gov)victalinom@niehs.nih.gov Leroy Worth, Scientific Review Officer, NIEHS (worth@niehs.nih.gov)worth@niehs.nih.gov Contributors: Michelle Heacock, Health Scientist, NIEHS Beth Anderson, Program Analyst, NIEHS 1 Link to RFA: http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.htmlhttp://grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.html Link to RFA Information Page: http://www.niehs.nih.gov/research/supported/dert/cris/programs/srp/funding/rfa/index.cfm http://www.niehs.nih.gov/research/supported/dert/cris/programs/srp/funding/rfa/index.cfm Link to RFA: http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.htmlhttp://grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.html Link to RFA Information Page: http://www.niehs.nih.gov/research/supported/dert/cris/programs/srp/funding/rfa/index.cfm http://www.niehs.nih.gov/research/supported/dert/cris/programs/srp/funding/rfa/index.cfm June 27, 2014

2. Today’s Focus: RFA Re-Release Updates 2 Notice to terminate RFA-ES-14-001: Posted May 16, 2014 RFA Re-released as RFA-ES-14-007: Posted June 12, 2014

3. Funding Opportunity Webinar – P42 Center RFA - Rerelease 3 Agenda Update of Changes in RFA (20 minutes) – General and Training-specific: Dr. Danielle Carlin – Training Review Criteria and Budget: Dr. Heather Henry Question / Answer (30 minutes) Agenda Update of Changes in RFA (20 minutes) – General and Training-specific: Dr. Danielle Carlin – Training Review Criteria and Budget: Dr. Heather Henry Question / Answer (30 minutes)

4. RFA Re-Release – General Updates Clarifications: – “Relation to Overall Center" statement is in the Research Strategy section and is part of the 12 page limit for that section. The length of the statement is not specified in RFA-ES-14-007 (RFA-ES-14-001 specified 1 page limit). – “Community Engagement Statement” goes in the Research Strategy for Community Engagement Cores and Community Engagement Research Projects. – Travel to annual meeting – Admin Core Budget should include travel for Center Director, Center Administrator, Training Core leader, Research Translation Core leader, Community Engagement Core leader, and four trainees. – Project Narrative for all projects and cores (except Training Core). Clarifications: – “Relation to Overall Center" statement is in the Research Strategy section and is part of the 12 page limit for that section. The length of the statement is not specified in RFA-ES-14-007 (RFA-ES-14-001 specified 1 page limit). – “Community Engagement Statement” goes in the Research Strategy for Community Engagement Cores and Community Engagement Research Projects. – Travel to annual meeting – Admin Core Budget should include travel for Center Director, Center Administrator, Training Core leader, Research Translation Core leader, Community Engagement Core leader, and four trainees. – Project Narrative for all projects and cores (except Training Core). 4

5. RFA Re-Release – General Updates Do not include “Table of All Personnel” in the Overall “Other Attachments”. This was eliminated because ASSIST will automatically generate a list of all personnel. Table of Trainees is no longer a part of the Training Core “Other Attachments”. It is now called the “Trainee List” and must be included in the Training Core “Progress Report” section (for competitive renewal applications only). New Biographical Sketches: DOES NOT APPLY to this RFA; applies to all NIH grant applications planned for FY 2016 and beyond. NOT ES 14-009: Only one application per institute is allowable. Do not include “Table of All Personnel” in the Overall “Other Attachments”. This was eliminated because ASSIST will automatically generate a list of all personnel. Table of Trainees is no longer a part of the Training Core “Other Attachments”. It is now called the “Trainee List” and must be included in the Training Core “Progress Report” section (for competitive renewal applications only). New Biographical Sketches: DOES NOT APPLY to this RFA; applies to all NIH grant applications planned for FY 2016 and beyond. NOT ES 14-009: Only one application per institute is allowable. 5

6. Goals and purpose of Training Core remains unchanged Training Core must follow Ruth L. Kirschstein National Research Service Award (NRSA) Application Guidelines with modifications specified in the RFA. What’s New – Use (NRSA) ASSIST Application Component and Budget – Recruitment & Retention Plan to Enhance Diversity – Plan for Responsible Conduct of Research – Trainee List (required only for renewals) What’s Modified – Review criteria – Budget – Sections/Page Limits Goals and purpose of Training Core remains unchanged Training Core must follow Ruth L. Kirschstein National Research Service Award (NRSA) Application Guidelines with modifications specified in the RFA. What’s New – Use (NRSA) ASSIST Application Component and Budget – Recruitment & Retention Plan to Enhance Diversity – Plan for Responsible Conduct of Research – Trainee List (required only for renewals) What’s Modified – Review criteria – Budget – Sections/Page Limits 6 RFA Re-Release – Training Updates SRP Training Core ≠ NRSA SRP TCs must adapt to NRSA Forms, but much of prior application’s text should be sufficient. SRP Training Core ≠ NRSA SRP TCs must adapt to NRSA Forms, but much of prior application’s text should be sufficient.

7. Training Core Function: Graduate and Post-doctoral level cross-disciplinary training Training Core Function: Graduate and Post-doctoral level cross-disciplinary training Training Core: Goals Unchanged Cost Limitations: New Applicants: $100,000 Direct Costs Renewal Applicants: $125,000 Direct Costs Promote interactions between biomedical and environmental science/engineering trainees Professional development Communicating research effectively Involvement in Research Translation, Community Engagement, etc. Achieves program integration Promote interactions between biomedical and environmental science/engineering trainees Professional development Communicating research effectively Involvement in Research Translation, Community Engagement, etc. Achieves program integration Inquiring Reviewers want to know: Recruitment? Past trainee successes Use of CareerTrac (for renewals) “Suggested Research and Activities” document http://www.niehs.nih.gov/research/supported/srp/funding/rfa.cfm) http://www.niehs.nih.gov/research/supported/srp/funding/rfa.cfm

8. 8 P42 Funding Opportunity Announcement 8 Must Use “NRSA Training” component for the Training Core. The Training Core is 25 pages (i.e., 25 pages include Background, Program Plan, and Recruitment and Retention Plan to Enhance Diversity).

9. NRSA Training Component - Information page 9 Look for ‘NRSA Training’ in the menu Follow RFA-ES-14- 007 instructions (and SF424 instructions, where applicable) for each ‘Tab’

10. 10 See next slides with instructions for filling out these attachments No Data Tables for this RFA. Biosketches

11. Training Core Follow Section “8.7” in the SF424 (R&R) Supplemental Instructions for Preparing Institutional Ruth L. Kirschstein National Research Service Award (NRSA): Introduction to Application: For Resubmission applications only. Background – Provide the rationale for the Training Core and the need for the cross- training proposed. – Indicate how the Training Core will relate to current training activities at the applicant institution. Program Plan – Program Administration – Program Faculty – Proposed Training – Program Evaluation – Trainee Candidates – Institutional Environment and Commitment to the Program 11 Page Limit = 25 Includes Background, Program Plan, and Recruitment and Retention Plan to Enhance Diversity (Attachments 2-4 of Research Training Program Plan form). Page Limit = 25 Includes Background, Program Plan, and Recruitment and Retention Plan to Enhance Diversity (Attachments 2-4 of Research Training Program Plan form). Note: NRSA Tables are not applicable to this FOA.

12. Training - Program Plan Program Administration – Strengths of the Training Core Leader – Planned strategy and administrative structure to oversee and monitor the core Program Faculty – Include information about Center faculty who will serve as preceptors/mentors and provide guidance and expertise appropriate to the level of trainees proposed in the application. – Describe the complementary expertise and experiences of the proposed Center Faculty. – For any proposed Center Faculty lacking research training experience, describe a plan to ensure successful trainee guidance by these individuals. – Describe the criteria used to appoint and remove Center Faculty and to evaluate their participation. 12 Note: Program Plan should be saved as a single file

13. Proposed Training – Overview of the Training Core – Objectives and activities – Training level and proposed number of trainees – Reflect the interdisciplinary nature of the Center Use of interdisciplinary approaches to training Opportunities to develop the trainees’ current research/activities to enhance their own professional career development and to receive training on best practices in Responsible Conduct of ResearchResponsible Conduct of Research Reporting of information about the Center’s trainees to the SRP Recruitment plan for all trainees (see also "Diversity Recruitment and Retention Plan”) 13 Training - Program Plan (Cont’d)

14. Program Evaluation – Plan to review and determine the quality and effectiveness of the Training Core – Include the utilization and frequency for trainee information submission to NIH CareerTrac (https://careertrac.niehs.nih.gov/)https://careertrac.niehs.nih.gov/ – Metrics to be evaluated (e.g., Core activities completed, degree completion, publications, fellowships/honors, and subsequent post-training positions) – Feedback from current and former trainees to help identify weaknesses/strengths Trainee Candidates – Size and qualifications of the trainee candidate pool – Plan to recruit candidates and implementation (see also section on Recruitment and Retention Plan to Enhance Diversity) 14 Training - Program Plan (Cont’d)

15. Institutional Environment and Commitment to the Program – Sponsoring institution must assure support for the proposed Training Core (assurance that sufficient time will be allowed for the Training Core Leader and other Center Faculty to contribute to the proposed training) – SRP Training Core is distinctive from existing Training Programs; indicate synergy between programs, if applicable 15 Training - Program Plan (Cont’d) Timeline and Milestones: The Training Core description should indicate the frequency for trainee information submission/updates to the NIH CareerTrac database. "Relation to Overall Center" statement within the Program Plan State the relevance of the core to the goals of the overall Center, how this core integrates with other projects and cores, and how the findings/activities of this core assist in solving the problem(s) that the Center is addressing. "Relation to Overall Center" statement within the Program Plan State the relevance of the core to the goals of the overall Center, how this core integrates with other projects and cores, and how the findings/activities of this core assist in solving the problem(s) that the Center is addressing.

16. Recruitment and Retention Plan to Enhance Diversity – Follow instructions as provided in Chapter 8 of the SF424 (R&R) Application Guide – Include description of plans to recruit a diverse trainee pool and may wish to include data in support of past accomplishments – Information should be included on both successful and unsuccessful recruitment strategies (as applicable) – Note – this used to be a separate attachment in the Training Core. Plan for Instruction in the Responsible Conduct of Research – Follow instructions as provided in Chapter 8 of the SF424 (R&R) Application Guide. General plan description is acceptable. Utilizing/referencing existing institutional training (including online) is acceptable. 16 Training Core

17. Training Core - Renewals Progress Report (Renewal Applications Only): As part of your progress report, provide a "Trainee List” (Note – this used to be a separate attachment in the Training Core). Identify the graduate students and post-doctoral researchers who participated in the Training Core during the previous funding cycle. – Include the names of the trainees, their SRP Center-associated mentor name, project/core. – All trainees should be entered into NIH CareerTrac database: https://careertrac.niehs.nih.gov/. https://careertrac.niehs.nih.gov/ 17

18. 18 Example of a “Trainee List” found on “Tips for Applicants” webpage. http://www.niehs.nih.gov/research/supported/dert/pro grams/srp/funding/rfa/rfa_tips/index.cfm Example of a “Trainee List” found on “Tips for Applicants” webpage. http://www.niehs.nih.gov/research/supported/dert/pro grams/srp/funding/rfa/rfa_tips/index.cfm

19. Training Core - Review Criteria Training Program and Environment – Objectives, design, and direction – Approaches and methods employed to develop the training curriculum and reflect the interdisciplinary nature of Center – Institutional commitment Training Leadership PD(s)/PI(s) – Experience in development of training programs – Encouragement of trainees to participate in professional development and/or leadership opportunities – Plan for communicating with SRP about training activities and trainees – For renewal applications, tracking of trainees (e.g. in CareerTrac) and their accomplishments 19 Score based on review criteria below and its contribution to Overall SRP Center Note: Individual criterion scores will not be provided (this is for all Cores)

20. Preceptors/Mentors – Project and Core Leaders as strong preceptors/mentors – Plans to ensure that preceptors lacking sufficient research training experience will be successful mentors Trainees – Plans for recruitment of trainees – Research/activities supported by the Center listed within the Training Core Training Record – Success of trainees in completing their research programs – Productivity: e.g. research accomplishments, publications, fellowship or career development awards, achievement of career goals, scientific leadership positions, etc. – Plan to assess the quality and effectiveness of the training 20 Training Core (Updated) - Review Criteria

21. Recruitment & Retention Plan to Enhance Diversity – Evaluation of recruitment and retention plan to enhance diversity and strategies to enhance diversity Training in the Responsible Conduct of Research – Plan to fulfill NIH requirements for instruction in the Responsible Conduct of Research (RCR) – Relation to the five instructional parts outlined in the NIH Policy on Training in the RCR: format, subject matter, faculty participation, duration, and frequency 21 Additional Review Considerations Reviewers will consider the following items, but will not consider them in providing an overall impact/priority score Rated as Acceptable or Unacceptable Additional Review Considerations Reviewers will consider the following items, but will not consider them in providing an overall impact/priority score Rated as Acceptable or Unacceptable

22. Note: Recommend place trainees on project/core budgets 22 Part A: If trainee is covered by the training core: Use the stipend category to request “salary” for the trainees Stipend expected to be consistent with trainee salaries listed in Projects and Cores and NIH policy "Tuition/Fees" in should be consistent with trainee Tuition/Fees from Project and Core budgets. Note: NRSA stipend levels do not apply to this FOA. Part A: If trainee is covered by the training core: Use the stipend category to request “salary” for the trainees Stipend expected to be consistent with trainee salaries listed in Projects and Cores and NIH policy "Tuition/Fees" in should be consistent with trainee Tuition/Fees from Project and Core budgets. Note: NRSA stipend levels do not apply to this FOA. Note: The SRP mandates specify that training is graduate-level and is not intended for undergraduates.

23. 23 Part B: Include expenses associated with the training core (such as salary support for Training Core Leader and other staff, consultant costs, equipment, research supplies, staff travel, etc.) in the "Training Related Expenses." Part B: Include expenses associated with the training core (such as salary support for Training Core Leader and other staff, consultant costs, equipment, research supplies, staff travel, etc.) in the "Training Related Expenses." F. Budget Justification Indicate the total number of trainees participating in the Training Core, including those whose salary/costs are being covered in their respective research projects/cores Provide details on level of effort and salary of core leader/staff, description other expenses, etc. in the justification section. Be sure to provide a breakdown of the Training Related Expenses. F. Budget Justification Indicate the total number of trainees participating in the Training Core, including those whose salary/costs are being covered in their respective research projects/cores Provide details on level of effort and salary of core leader/staff, description other expenses, etc. in the justification section. Be sure to provide a breakdown of the Training Related Expenses. Note: 8% NRSA indirect cost rates do not apply to this FOA.

24. 24 All values on this form are calculated automatically NRSA training budget will be rolled up into the Composite Budget and the Overall Budget summaries.

25. Frequently Asked Questions and Tips 25 Frequently Asked Questions – posted on http://www.niehs.nih.gov/research/supported/ dert/programs/srp/funding/rfa/ http://www.niehs.nih.gov/research/supported/ dert/programs/srp/funding/rfa/ Frequently Asked Questions – posted on http://www.niehs.nih.gov/research/supported/ dert/programs/srp/funding/rfa/ http://www.niehs.nih.gov/research/supported/ dert/programs/srp/funding/rfa/ Application Tips: http://www.niehs.nih.gov/research/supported/dert/prog rams/srp/funding/rfa/rfa_tips/index.cfm http://www.niehs.nih.gov/research/supported/dert/prog rams/srp/funding/rfa/rfa_tips/index.cfm Application Tips: http://www.niehs.nih.gov/research/supported/dert/prog rams/srp/funding/rfa/rfa_tips/index.cfm http://www.niehs.nih.gov/research/supported/dert/prog rams/srp/funding/rfa/rfa_tips/index.cfm

26. More on ASSIST 26 Follow all special instructions noted in Section IV. of the announcement. The eRA validations will catch many, but not all, submission requirements. FOA-specific requirements are not typically system-enforced. Applications that do not comply with the instructions may be delayed or not accepted for review. http://grants.nih.gov/grants/ElectronicReceipt/avoiding_ errors.htm Follow all special instructions noted in Section IV. of the announcement. The eRA validations will catch many, but not all, submission requirements. FOA-specific requirements are not typically system-enforced. Applications that do not comply with the instructions may be delayed or not accepted for review. http://grants.nih.gov/grants/ElectronicReceipt/avoiding_ errors.htm Will process application with wrong/expired RFA number – be sure to use: RFA-ES-14-007. Will NOT automatically roll your old application into the new RFA. You must reload the entire application. Will allow you to add attachments that are not allowed/required. Any additional/extra attachments not required in the RFA may cause your application to be rejected by CSR or NIEHS. Take Home Message – please submit at least a week before due date and make sure everything is there that should be (and nothing more). Will process application with wrong/expired RFA number – be sure to use: RFA-ES-14-007. Will NOT automatically roll your old application into the new RFA. You must reload the entire application. Will allow you to add attachments that are not allowed/required. Any additional/extra attachments not required in the RFA may cause your application to be rejected by CSR or NIEHS. Take Home Message – please submit at least a week before due date and make sure everything is there that should be (and nothing more).

27. Resources RFA Webpage: http://www.niehs.nih.gov/research/supported/dert/programs/srp/fundin g/rfa/ http://www.niehs.nih.gov/research/supported/dert/programs/srp/fundin g/rfa/ SF424 (R&R) Application and Electronic Submission Information” webpage: – http://grants.nih.gov/grants/funding/424/index.htm http://grants.nih.gov/grants/funding/424/index.htm Applying Electronically to Multi-project Applications: – http://grants.nih.gov/grants/ElectronicReceipt/com_index.htm http://grants.nih.gov/grants/ElectronicReceipt/com_index.htm Need help with ASSIST? – http://grants.nih.gov/grants/ElectronicReceipt/faq_full.htm#about http://grants.nih.gov/grants/ElectronicReceipt/faq_full.htm#about 27 eRA Commons - https://commons.era.nih.gov/commons/index.jsphttps://commons.era.nih.gov/commons/index.jsp Registered PD/PIs can check assignment/contact information, review outcome, and other important information. eRA Commons Help Desk: Hours: Mon-Fri, 7AM-8PM EDT/EST Web: http://era.nih.gov/help/ Toll-free: 866-504- 9552. Phone: 301-402-7469. TTY: 301-451-5939.http://era.nih.gov/help/ eRA Commons - https://commons.era.nih.gov/commons/index.jsphttps://commons.era.nih.gov/commons/index.jsp Registered PD/PIs can check assignment/contact information, review outcome, and other important information. eRA Commons Help Desk: Hours: Mon-Fri, 7AM-8PM EDT/EST Web: http://era.nih.gov/help/ Toll-free: 866-504- 9552. Phone: 301-402-7469. TTY: 301-451-5939.http://era.nih.gov/help/ PLEASE PRINT THIS AND KEEP A COPY HANDY!!!!!

28. NIEHS Contacts: Program: William A. Suk suk@niehs.nih.gov, (919) 541-0797suk@niehs.nih.gov Heather Henry henryh@niehs.nih.gov, (919) 541-5330henryh@niehs.nih.gov Danielle Carlin danielle.carlin@nih.gov, (919) 541-1409danielle.carlin@nih.gov Grants Management: Lisa Edwards, archer@niehs.nih.gov, (919) 541-0751archer@niehs.nih.gov Michelle Victalino, victalinom@niehs.nih.gov, (919) 316-4666victalinom@niehs.nih.gov Scientific Review: Leroy Worth, worth@niehs.nih.gov, (919) 541-0670worth@niehs.nih.gov NIEHS Contacts: Program: William A. Suk suk@niehs.nih.gov, (919) 541-0797suk@niehs.nih.gov Heather Henry henryh@niehs.nih.gov, (919) 541-5330henryh@niehs.nih.gov Danielle Carlin danielle.carlin@nih.gov, (919) 541-1409danielle.carlin@nih.gov Grants Management: Lisa Edwards, archer@niehs.nih.gov, (919) 541-0751archer@niehs.nih.gov Michelle Victalino, victalinom@niehs.nih.gov, (919) 316-4666victalinom@niehs.nih.gov Scientific Review: Leroy Worth, worth@niehs.nih.gov, (919) 541-0670worth@niehs.nih.gov P42 Multi-Project Centers 28

29. Thank You! QUESTIONS?? Webinar Gurus Jean Balent, EPA TIFSD Justin Crane, MDB, Inc. Kevin O’Donovan Webinar Gurus Jean Balent, EPA TIFSD Justin Crane, MDB, Inc. Kevin O’Donovan SRP Team Bill Suk, Director Danielle Carlin Heather Henry Beth Anderson Michelle Heacock Rosemary Moody SRP Team Bill Suk, Director Danielle Carlin Heather Henry Beth Anderson Michelle Heacock Rosemary Moody NIEHS Staff Leroy Worth, SRO Alfonso Latoni, Review Chief Lisa Archer Edwards, GMO Michelle Victalino, GMS Gwen Collman, DERT Director NIEHS Staff Leroy Worth, SRO Alfonso Latoni, Review Chief Lisa Archer Edwards, GMO Michelle Victalino, GMS Gwen Collman, DERT Director Questions not covered during seminar will be answered off-line ASAP and posted on P42 Funding Opportunity Webpages. Audio Archive will be available in approximately 2 weeks and are accessible from the above website. Questions not covered during seminar will be answered off-line ASAP and posted on P42 Funding Opportunity Webpages. Audio Archive will be available in approximately 2 weeks and are accessible from the above website.

30. Slides from January 2014 Webinar Updates indicated in RED TEXT 30

31. SRP Funding Mechanisms Multi-Project Centers (P42) Designed for integration across disciplines: Biomedical and Non- Biomedical Research; Community Engagement, Research Translation, and Training. Basic and application-oriented. Request for Applications. Annual RFA. Multi-Project Centers (P42) Designed for integration across disciplines: Biomedical and Non- Biomedical Research; Community Engagement, Research Translation, and Training. Basic and application-oriented. Request for Applications. Annual RFA. Individual Research Project (R01) Designed to address specific issues to complement the multi-project research program; tackle issues of emerging concern for Superfund. Closed. Individual Research Project (R01) Designed to address specific issues to complement the multi-project research program; tackle issues of emerging concern for Superfund. Closed. Small Business Research Grants SBIR/STTR (R41-44) Foster the commercialization of technologies, relevant to hazardous substance clean-up and monitoring. Ongoing Funding Opportunity Small Business Research Grants SBIR/STTR (R41-44) Foster the commercialization of technologies, relevant to hazardous substance clean-up and monitoring. Ongoing Funding Opportunity 31 Conference Grants (R13) Provides funding for conferences related to SRP mandates. Ongoing Funding Opportunity Conference Grants (R13) Provides funding for conferences related to SRP mandates. Ongoing Funding Opportunity Funding Opportunities: http://www.niehs.nih.gov/research/supported/dert/cris/programs/srp/funding/index.cfmhttp://www.niehs.nih.gov/research/supported/dert/cris/programs/srp/funding/index.cfm Occupational Training (R25) Emerging issues in EHS training. Closed. Occupational Training (R25) Emerging issues in EHS training. Closed.

32. SRP Mandates under SARA Development of: Advanced techniques for the detection, assessment, and evaluation of the human health effects of hazardous substances Methods to assess the risks to human health presented by hazardous substances Methods and technologies to detect hazardous substances in the environment Basic biological, chemical, and physical methods to reduce the amount and toxicity of hazardous substances Development of: Advanced techniques for the detection, assessment, and evaluation of the human health effects of hazardous substances Methods to assess the risks to human health presented by hazardous substances Methods and technologies to detect hazardous substances in the environment Basic biological, chemical, and physical methods to reduce the amount and toxicity of hazardous substances 32 University-based basic research program established in 1986 under Superfund Amendments Reauthorization Act (SARA) Health Effects Assessing Risks Detection Remediation

33. SRP Strategic Plan (2010) Relevance – Interaction with stakeholders – Problem-based, solution-oriented research – Critical research areas Impact Innovation http://www.niehs.nih.gov/research/supported/assets/docs/r_s/srp_about_2010_plan.pdf SRP Stakeholders Sister Superfund Programs: US Environmental Protection Agency (EPA) Agency for Toxic Substances and Disease Registry (ATSDR) Others: federal agencies, state, local, and tribal entities responsible for sites; individuals and communities living near hazardous waste sites SRP Stakeholders Sister Superfund Programs: US Environmental Protection Agency (EPA) Agency for Toxic Substances and Disease Registry (ATSDR) Others: federal agencies, state, local, and tribal entities responsible for sites; individuals and communities living near hazardous waste sites 33

34. RFA-ES-14-007 SUPERFUND HAZARDOUS SUBSTANCE RESEARCH AND TRAINING PROGRAM (P42) 34 Improve public health by supporting integrative, inter-disciplinary research. Provide sound science, data, information, and knowledge to inform the risk assessment and remediation management processes for hazardous waste sites. Provide sound science, data, information, and knowledge to inform the risk assessment and remediation management processes for hazardous waste sites. P42 Multi-Project Centers Bring expertise of multiple biomedical and environmental science disciplines to address scientific uncertainties facing the National Superfund Program.

35. Community Engagement Research Translation Problem Solution Environmental Science and Engineering Biomedical Science P42 Multi-Project Centers Superfund Stakeholders Stakeholder Communities 35 Research and Training

36. P42 Multi-Project Centers Scope of Research SRP Mandates Advanced techniques for the detection, assessment, and evaluation of the effect of hazardous substances on human health Methods to assess the risks to human health presented by hazardous substances Methods and technologies to detect hazardous substances in the environment Basic biological, chemical, and physical methods to reduce the amount and toxicity of hazardous substances SRP Mandates Advanced techniques for the detection, assessment, and evaluation of the effect of hazardous substances on human health Methods to assess the risks to human health presented by hazardous substances Methods and technologies to detect hazardous substances in the environment Basic biological, chemical, and physical methods to reduce the amount and toxicity of hazardous substances Strategic Plan Relevance: to Superfund Impact: to Stakeholders Innovation: Trans-disciplinary/Paradigm-shifting Strategic Plan Relevance: to Superfund Impact: to Stakeholders Innovation: Trans-disciplinary/Paradigm-shifting 36 Programmatic Balance (See Current Grantees: http://tools.niehs.nih.gov/sr p/programs/index267.cfm ) Programmatic Balance (See Current Grantees: http://tools.niehs.nih.gov/sr p/programs/index267.cfm ) Broad Scope – Ultimately should be a clear link to Superfund. Broad Scope – Ultimately should be a clear link to Superfund. Suggested Research Topics: High priority areas for EPA/ATSDR colleagues Not Required: Superfund Site; CERCLA Substance

37. Community Engagement Core Administrative Core Research Translation Core Biomedical (≥ 2 Projects) Biomedical (≥ 2 Projects) Environmental Science and Engineering (≥ 2 Projects) Environmental Science and Engineering (≥ 2 Projects) Training Core Research Support Core(s) optional P42 Multi-Project Centers All Components Interacting, Addressing Problem New Proposals: up to $1.6M/year direct costs for 4 years Renewal Proposals: up to $2.0M/year direct costs for 5 years New Proposals: up to $1.6M/year direct costs for 4 years Renewal Proposals: up to $2.0M/year direct costs for 5 years 37 Total: 8 - 12 Components

38. Health Effects Epidemiology Mechanistic Toxicology Fate and Transport Hydrogeology Remediation Engineering Biomedical (≥ 2 Projects) Environmental Science and Engineering (≥ 2 Projects) P42: Projects 38 Each project is stand-alone independent testable hypothesis logical progression of tasks Basic to application - oriented Integration with other projects Research Aims Sharing: data, specimens, technology Interaction with Cores Training, Community Engagement Research Translation (including investigator- initiated research translation)

39. 39 P42: Projects Interactions: Cross-reference interactions between projects and cores. Should be consistent throughout. Abstract / Titles – Avoid Jargon P42 Reviewers have broad expertise Write abstracts/titles for a general audience Write Specific Aims for technical experts http://grants.nih.gov/grants/plain_language.htm FOCUS!!!! Centers should be VERY judicious in assembling research projects. Center should, with projects, keep a clear focus and not try to do too much!! Include projects with most solid connection to the Center’s problem-solving theme. Lean Times: Not too big! Come in under budget, well under 12-component limit. Especially True for New Center Proposals!

40. 40 http://www.niehs.nih.gov/research/supported/dert/programs/srp/funding/rfa/index.cfm P42: Projects NEW: for investigators to explore opportunities for sharing research products and broad opportunities for research translation during project development. 1 paragraph PLAN for each: Resource Sharing Plans Research Data Sharing Plan: Publication-based data-sharing opportunities; databases Explain if sharing not appropriate. Must follow all NIH required data- sharing. See “Suggested Research and Activities” for Investigator- Initiated Research Translation suggestions. Investigator-Initiated Research Translation Plan: Identify potential interactions between researcher and end-user (not researcher to researcher) drawing from SRP’s 4 research translation components. (Consistency with RTC).

41. P42: Administrative Core (Required) 41 Administrative Core (AC) Functions – Planning and coordination – Promote cross-discipline interaction – Ensure research translation – Oversee fiscal and quality management Administrative Core (AC) Functions – Planning and coordination – Promote cross-discipline interaction – Ensure research translation – Oversee fiscal and quality management External Advisory Committee (EAC) – Provides Guidance to Director – Scientific Merit – Relevance, Integration – Research Translation, Community Engagement, Training activities External Advisory Committee (EAC) – Provides Guidance to Director – Scientific Merit – Relevance, Integration – Research Translation, Community Engagement, Training activities Anticipated EAC Members* Academics (biomedical AND environmental science and engineering), Stakeholders, EPA/ATSDR, Industry, Community Anticipated EAC Members* Academics (biomedical AND environmental science and engineering), Stakeholders, EPA/ATSDR, Industry, Community *New Applicants: include expertise of potential EAC members, not names Not to exceed $125,000 Direct Costs AC Breaks Silos Between Disciplines Basic to Applied Lab to End-user AC Promotes Careers Trainees, Early Stage Investigators, Succession Planning (if applicable)

42. Research Translation Core (Required) Research Translation Core Function: Communicating and facilitating the use of research findings emanating from the Center in the manner most appropriate for their application and the advancement of research objectives. Research Translation Core Function: Communicating and facilitating the use of research findings emanating from the Center in the manner most appropriate for their application and the advancement of research objectives. 42 Include Plan for Four Components 1.Communication 2.Government Partnerships 3.Technology Transfer 4.Information Dissemination Include Plan for Four Components 1.Communication 2.Government Partnerships 3.Technology Transfer 4.Information Dissemination Note: SRP Research Translation – much broader scope than NIH’s Clinical Translation (bench to bedside). Not to exceed $125,000 Direct Costs Information from Center to Center as well as Center outward (to all end-users) Plan for Reporting News to SRP: For Example: reporting to the SRP Data Collection Form: http://tools.niehs.nih.gov/srp/resources/rtc.cfm See Suggested Research and Activities Document for ideas for the RTCs: http://www.niehs.nih.gov/research/supported/dert/programs/srp/funding/rfa/index.cfm See Suggested Research and Activities Document for ideas for the RTCs: http://www.niehs.nih.gov/research/supported/dert/programs/srp/funding/rfa/index.cfm

43. 2.Partnerships with Government Agencies Research Translation Core (RTC) 43 4. Information Dissemination to Other End-Users End-Users: formal/informal education groups, hazardous waste practitioners, lay public, other academic researchers Examples: Educational materials, Web sites, webinars, “outreach,” etc. Where to start? SRP’s Additional Resources Webpage* Find your EPA Region’s Superfund Technical Liaison / ATSDR staff Superfund Site Remedial Project Manager 1. Communicating within SRP a. Project-Specific: Within Center b. Center-Specific: Center Out c. Between Center/SRP d. Between Centers 1. Communicating within SRP a. Project-Specific: Within Center b. Center-Specific: Center Out c. Between Center/SRP d. Between Centers EPA/ATSDR a priority, but not a requirement. Expertise: staff with experience in diverse science topics. RTC – work with investigators on research translation plan for each project (clusters of projects). * http://www.niehs.nih.gov/research/supported/srp/funding/rfa/index.cfm

44. Community Engagement Core Function : To enhance knowledge exchange and to support community needs with regard to the science emanating from the Center Community Engagement Core Function : To enhance knowledge exchange and to support community needs with regard to the science emanating from the Center Community Engagement Core (Required) Target communities SRP defines target communities as those impacted by sites contaminated with hazardous substances. Members of the affected community May also include: local government, tribal councils, community service groups, non-governmental organizations Target communities SRP defines target communities as those impacted by sites contaminated with hazardous substances. Members of the affected community May also include: local government, tribal councils, community service groups, non-governmental organizations 44 Not to exceed $100,000 Direct Costs A Community Engagement Component Statement must be included in application. HIGHLIGHT “Bidirectionality” between community and Center (not “outreach”) Where to start? SRP Additional Resources Webpage* Suggested Research and Activities Document Develop logic model * http://www.niehs.nih.gov/research/supported/srp/funding/rfa/index.cfm

45. 45 Theme of Center Impacted Community BIDIRECTIONAL Research Products Appropriate Application ITERATIVE End-users Research Translation Initiated by the Center (RTC/Investigator) Based on research “product” Opportunistic and Rapid Response Critical role reporting successes Initiated by the Center (RTC/Investigator) Based on research “product” Opportunistic and Rapid Response Critical role reporting successes Partnership-driven Finite/Defined Activities Provide access to expertise or conduct community-based projects Partnership-driven Finite/Defined Activities Provide access to expertise or conduct community-based projects Community Engagement Shared Challenge: Finding the most Appropriate End-User / Community Group for Center Research and Activities

46. Training Core Function: Graduate and Post-doctoral level cross-disciplinary training Training Core Function: Graduate and Post-doctoral level cross-disciplinary training Training Core (Required) 46 Cost Limitations: New Applicants: $100,000 Direct Costs Renewal Applicants: $125,000 Direct Costs Promote interactions between biomedical and environmental science trainees Professional development Communicating research effectively Involvement in Research Translation, Community Engagement, etc. Achieves program integration Promote interactions between biomedical and environmental science trainees Professional development Communicating research effectively Involvement in Research Translation, Community Engagement, etc. Achieves program integration Inquiring Reviewers want to know: Recruitment? Past trainee successes Use of CareerTrac (for renewals) Please refer to Training Core Changes section of webinar for Format Changes in ES-14-007

47. Research Support Core – Provides centralized services – Shared by at least 2 projects Research Support Core – Provides centralized services – Shared by at least 2 projects P42: Research Support Core (Optional) 47 Pros and Cons of RSC – Pros: – Excellent Interactions/Integration – Opportunities for Training – Assurance of Quality – Cons: – May not be critical (if facilities already available) – 12 component limit If Research Support Core is not included, project should adequately detail research support activities (e.g. QA/QC)

48. Cost Limitations (Direct) Core Limitations (Direct): Administrative - $125K Research Translation - $125K Community Engagement - $100K Training Cores – New applicants: $100K – Renewal applicants: $125K Core Limitations (Direct): Administrative - $125K Research Translation - $125K Community Engagement - $100K Training Cores – New applicants: $100K – Renewal applicants: $125K 48 Cores Sum ≤ 20% Total Center Administrative Research Translation Community Engagement Training Center: New Applicants: up to $1.6M/year direct costs for 4 years Renewal Applicants: up to $2.0M/year direct costs for 5 years Center: New Applicants: up to $1.6M/year direct costs for 4 years Renewal Applicants: up to $2.0M/year direct costs for 5 years Renewal Applicants: ≤ $400K Renewal Applicants: ≤ $400K 20% AC, RTC, CEC, TC 80% Research Projects, Research Support Cores New Applicants: ≤ $320K New Applicants: ≤ $320K

49. Budget Ceilings for Overall Center and Cores Total Projects and Cores limited to 12 Components Training Cores required Research Support Cores optional Environmental Science and Engineering replaced “Environmental Science” and “Non-biomedical” Budget Ceilings for Overall Center and Cores Total Projects and Cores limited to 12 Components Training Cores required Research Support Cores optional Environmental Science and Engineering replaced “Environmental Science” and “Non-biomedical” Recent Changes 49 Resource Sharing Plan for Projects Review Criteria Changes Modifications to overall center description of Significance, Investigator, Innovation, Approach and Environment Cores: each core has specific review criteria

50. Recent Changes Research Translation Core – Translation plan for each project Research Strategy (12 page limit) Review Scoring System One Resubmission (A1) Community Engagement – Core is Required – Community Engagement Projects (CEPs) explicitly mentioned (had always been welcome) e.g. community-based participatory research (biomedical and environmental science) – New: “Community Engagement Component Statement” section for CEC and CEPs. Research Translation Core – Translation plan for each project Research Strategy (12 page limit) Review Scoring System One Resubmission (A1) Community Engagement – Core is Required – Community Engagement Projects (CEPs) explicitly mentioned (had always been welcome) e.g. community-based participatory research (biomedical and environmental science) – New: “Community Engagement Component Statement” section for CEC and CEPs. 50 Unchanged Characteristics Not a site-specific program Basic to application-oriented research Innovative approaches to research Unchanged Characteristics Not a site-specific program Basic to application-oriented research Innovative approaches to research

51. Community Engagement Research Translation Problem Solution Non-Biomedical Approaches Biomedical Approaches A Successful P42 Center Superfund Stakeholders Stakeholder Communities 51 Research and Training * Addressing Important Problem * Projects and Cores Uniformly Meritorious * Integration, Interaction, Synergy: -Biomedical and Environmental Science & Engineering -Projects and Cores * Integration, Interaction, Synergy: -Biomedical and Environmental Science & Engineering -Projects and Cores * Aids Stakeholders in Effective Decision-Making

52. NIEHS SCIENTIFIC PEER REVIEW LEROY WORTH, PHD (2014 P42 REVIEW ) Review 52

53. Non-responsive (return to applicant) Non-responsive (return to applicant) Responsive Review Committee Discussed Funding decisions and awards (June/July 2015) Funding decisions and awards (June/July 2015) Summary Statements Summary Statements Letters of Intent (August 3, 2014) Letters of Intent (August 3, 2014) NAEHS Council (May 2015) NAEHS Council (May 2015) Summary Statements Summary Statements Not - Discussed The Peer Review Process Administrative Review Peer Review Meeting (Winter 2015) Receive Applications (September 3, 2014) Receive Applications (September 3, 2014) 53

54. Submission of Letter of Intent (LOI): – Assists in review planning – Email to Dr. Leroy Worth at worth@niehs.nih.gov Requested by August 3, 2014 (not required, but highly recommended)worth@niehs.nih.gov Include in the LOI: – Descriptive title of the Overall Center Brief description of the research proposed in the Center Include the title of each Research Project and Core – Name, address, and telephone number of the PD(s)/PI(s) – Names of key personnel (Project and Core Leaders) – Names of any participating institutions Submission of Letter of Intent (LOI): – Assists in review planning – Email to Dr. Leroy Worth at worth@niehs.nih.gov Requested by August 3, 2014 (not required, but highly recommended)worth@niehs.nih.gov Include in the LOI: – Descriptive title of the Overall Center Brief description of the research proposed in the Center Include the title of each Research Project and Core – Name, address, and telephone number of the PD(s)/PI(s) – Names of key personnel (Project and Core Leaders) – Names of any participating institutions Pre-Submission of P42 Application 54

55. P42 Peer Review Process Review Criteria are in the solicitation: http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.html http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.html Review of the Individual Research Projects, Cores Review the Overall Center 55

56. Research Projects Significance Investigator(s) Innovation Approach Environment Contribution to SRP Center Other Specific Criteria* NIH’s Five Review Criteria (criterion scores 10-90) NIH’s Five Review Criteria (criterion scores 10-90) Impact Score (10-90) Impact Score (10-90) Each Project reviewed. Each Receive Criterion Scores and written critiques. Note- Applications not discussed will not be provided an overall impact score (e.g Center, individual Projects, and Cores). Note: Human Subjects, Animal Care, and Biohazards can be considered in the overall score. Budget Concerns are not considered in score. 56

57. Cores Contribution to SRP Center Other Criteria Specific to Each Core – Administrative – Research Translation Core – Community Engagement – Training (NOTE – see previous slides for review criteria changes from ES 14-001) – Research Support Cores (see RFA for specific criteria) Impact Score (10-90) Impact Score (10-90) 57

58. Overall Center Final Score (Range: 10-90) 58 Addresses a critical problem relevant to the SRP Relevance/Merit of Projects and Cores (scientific gain) Collaboration/Integration/Synergy Leadership Addresses a critical problem relevant to the SRP Relevance/Merit of Projects and Cores (scientific gain) Collaboration/Integration/Synergy Leadership

59. Helpful Hints Read and understand the Funding Announcement Contact Program Staff for clarification of scientific matters and Grants Management Staff for budget issues. Follow the guidelines: page limits, font size, etc. Start early………because: Any mistakes made with electronic submission (i.e., ASSIST) may cause your application to be returned without further deliberation by NIEHS Review staff. Read and understand the Funding Announcement Contact Program Staff for clarification of scientific matters and Grants Management Staff for budget issues. Follow the guidelines: page limits, font size, etc. Start early………because: Any mistakes made with electronic submission (i.e., ASSIST) may cause your application to be returned without further deliberation by NIEHS Review staff. 59

60. Grantsmanship Issues Be clear and concise….don’t expect reviewers to “know what you mean.” All the components are important. One weak research project will impact the overall score. Extraneous or unnecessary cores will reduce cohesiveness of the center. Too many projects…application sinks under its own weight. Inadequate time allowed to prepare application. Be clear and concise….don’t expect reviewers to “know what you mean.” All the components are important. One weak research project will impact the overall score. Extraneous or unnecessary cores will reduce cohesiveness of the center. Too many projects…application sinks under its own weight. Inadequate time allowed to prepare application. 60

61. NIEHS GRANTS MANAGEMENT LISA EDWARDS, MBA Budget 61

62. Electronic Budget Webinar for Applicants: Initial Look at the Electronic Submission Process of Multi-Project Applications http://grants.nih.gov/grants/webinar_docs/webinar_20121213.htm SF424 (R&R) Detailed Budget forms differ from Paper PHS398 Budget Forms in both look/feel and substance o Some items in different places o Some items not collected as specific line items Budget data collected at component and subaward levels only Component and subaward budget data used to auto-calculate “Cumulative” (Composite) budget Webinar for Applicants: Initial Look at the Electronic Submission Process of Multi-Project Applications http://grants.nih.gov/grants/webinar_docs/webinar_20121213.htm SF424 (R&R) Detailed Budget forms differ from Paper PHS398 Budget Forms in both look/feel and substance o Some items in different places o Some items not collected as specific line items Budget data collected at component and subaward levels only Component and subaward budget data used to auto-calculate “Cumulative” (Composite) budget 62

63. Budget Preparation *Just in Time: Request for information required prior to award. 63 Form Pages, Approvals, Other Support, Notices Forms (http://grants.nih.gov/grants/forms.htm)http://grants.nih.gov/grants/forms.htm SF424 (R&R) electronic submission Approvals IACUC Approval (Vertebrate Animals) IRB Approval (Human Subjects) Begin process at time of application, but final approval will be requested for Just In Time* Other Support “0%”, “Varies”, “As Needed”, etc., are not acceptable Total time commitment cannot exceed 12 calendar months Form Pages, Approvals, Other Support, Notices Forms (http://grants.nih.gov/grants/forms.htm)http://grants.nih.gov/grants/forms.htm SF424 (R&R) electronic submission Approvals IACUC Approval (Vertebrate Animals) IRB Approval (Human Subjects) Begin process at time of application, but final approval will be requested for Just In Time* Other Support “0%”, “Varies”, “As Needed”, etc., are not acceptable Total time commitment cannot exceed 12 calendar months New Notices Revised Grants Policy Statement: NOT-OD-12-157 Salary caps: NOT-OD-12-035 http://grants1.nih.gov/grants/po licy/salcap_summary.htm. New Notices Revised Grants Policy Statement: NOT-OD-12-157 Salary caps: NOT-OD-12-035 http://grants1.nih.gov/grants/po licy/salcap_summary.htm.

64. Travel to Annual Meeting Administrative Core Budget: Funds for travel by appropriate staff (i.e., Center Director, Project/Core Leaders, Center Administrator, and four trainees) to attend the Superfund Research Program three-day annual meeting shall be included in the Administrative Core’s budget for each year. Travel to Annual Meeting Administrative Core Budget: Funds for travel by appropriate staff (i.e., Center Director, Project/Core Leaders, Center Administrator, and four trainees) to attend the Superfund Research Program three-day annual meeting shall be included in the Administrative Core’s budget for each year. Escalation Budgets submitted in subsequent years may request an escalation on recurring direct costs. (Note: Currently NIH does provide an escalation in subsequent years) Must be justified: Is the amount of escalation requested supported by institutional policies? Is the amount clearly stated? Escalation Budgets submitted in subsequent years may request an escalation on recurring direct costs. (Note: Currently NIH does provide an escalation in subsequent years) Must be justified: Is the amount of escalation requested supported by institutional policies? Is the amount clearly stated? Budget Preparation 64 Non-Modular Provide detailed categorical budgets Each Project Each Core Each Subaward/Consortium (Note: SF424 will not allow Subawards on Subawards) For Training Budget Pages – NRSA Budget forms must be used. Please see previous slideset. Non-Modular Provide detailed categorical budgets Each Project Each Core Each Subaward/Consortium (Note: SF424 will not allow Subawards on Subawards) For Training Budget Pages – NRSA Budget forms must be used. Please see previous slideset.

65. Budget Preparation 65

66. 66

67. R&R Budget Sections A & B 67 Personnel separated into 2 sections: A. Senior/Key Person o First field must be completed, even if person on a component given role of “Project Leader” and not PD/PI B. Other Personnel o Postdocs, Grad Students, Undergrads: Only number of personnel required (not specific names) *Include only personnel employed by (e.g., receiving salary from) your organization. Personnel separated into 2 sections: A. Senior/Key Person o First field must be completed, even if person on a component given role of “Project Leader” and not PD/PI B. Other Personnel o Postdocs, Grad Students, Undergrads: Only number of personnel required (not specific names) *Include only personnel employed by (e.g., receiving salary from) your organization.

68. R&R Budget Sections C - E 68 Itemize up to 100 pieces of equipment. If more, include total dollars in line 11 and provide details in the Additional Equipment attachment Not required for P42

69. R&R Budget Sections C - E 69 Item D, Travel o 424 form differentiates between foreign and domestic travel o Continues to be treated as single cost (regardless of type) similar to 398 budget Item E, Participant/Trainee Support Costs o Do not use for NIH FOAs o Costs for NRSA Training-type components should use Training Budget form Item D, Travel o 424 form differentiates between foreign and domestic travel o Continues to be treated as single cost (regardless of type) similar to 398 budget Item E, Participant/Trainee Support Costs o Do not use for NIH FOAs o Costs for NRSA Training-type components should use Training Budget form

70. R&R Budget Sections F - K 70 Subaward/Consortium/Contractual Cost not pre- populated. Include both Total Direct and Indirect cost

71. R&R Budget Sections F-K 71 Tuition remission o Include in Item F, Other Direct Costs (boxes 8, 9 or 10) Supplies o Not a major line item on 424 budgets o Included as line F.1 (Other Direct Costs: Materials and Supplies) Alteration and Renovations o Not a major line item on 424 budgets o Included as line F.7 (Other Direct Costs: Alterations and Renovations) Inpatient and Outpatient Care Costs o 424 does not include as major / minor line item o Current instructions require inserting in fields F.8-F.10 (Other Direct Costs: Other Costs) Tuition remission o Include in Item F, Other Direct Costs (boxes 8, 9 or 10) Supplies o Not a major line item on 424 budgets o Included as line F.1 (Other Direct Costs: Materials and Supplies) Alteration and Renovations o Not a major line item on 424 budgets o Included as line F.7 (Other Direct Costs: Alterations and Renovations) Inpatient and Outpatient Care Costs o 424 does not include as major / minor line item o Current instructions require inserting in fields F.8-F.10 (Other Direct Costs: Other Costs)

72. 72

73. 73

74. P42 Multi-Project Centers Announcement: – RFA-ES-14-007: http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.html http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.html Applications Details – One application per institution – Letters of Intent: August 3, 2014 March 10, 2014 – Due Date: Sept 3, 2014 April 10, 2014 by 5:00 PM local time of applicant organization. – Scientific Review: Jan/Feb 2015 October, 2014 – Awards Start Date: June/July 2015 April, 2015 Consultation with SRP Program Administrator Staff is highly recommended (in person or teleconference) Announcement: – RFA-ES-14-007: http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.html http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.html Applications Details – One application per institution – Letters of Intent: August 3, 2014 March 10, 2014 – Due Date: Sept 3, 2014 April 10, 2014 by 5:00 PM local time of applicant organization. – Scientific Review: Jan/Feb 2015 October, 2014 – Awards Start Date: June/July 2015 April, 2015 Consultation with SRP Program Administrator Staff is highly recommended (in person or teleconference) 74

75. P42 Resources RFA Webpage – Suggested Research and Activities - Numerous areas of general interest as well as specific needs identified by stakeholders. – Tips for Applicants – electronic submission, what to include, etc. – Additional Resources – Links to EPA, ATSDR, information to aid in community engagement activities, and other helpful websites. – Program Contacts 75 Also see “Current P42 Grantees:” http://tools.niehs.nih.gov/srp/programs/index267.cfm http://tools.niehs.nih.gov/srp/programs/index267.cfm Also see “Current P42 Grantees:” http://tools.niehs.nih.gov/srp/programs/index267.cfm http://tools.niehs.nih.gov/srp/programs/index267.cfm RFA Webpage: http://www.niehs.nih.gov/research/supported/srp/funding/rfa/index.cfm http://www.niehs.nih.gov/research/supported/srp/funding/rfa/index.cfm RFA Webpage: http://www.niehs.nih.gov/research/supported/srp/funding/rfa/index.cfm http://www.niehs.nih.gov/research/supported/srp/funding/rfa/index.cfm

76. SRP PROGRAM ADMINISTRATOR DANIELLE CARLIN, PHD, DABT Electronic Submission: Using ASSIST 76 Note – There is additional information about ASSIST in the previous slides set.

77. What is ASSIST? 77 ASSIST - Application Submission System & Interface for Submission Tracking Web-based system for the preparation and submission of multi-project applications ASSIST replaces Grants.gov Grants.gov for single-project applications ASSIST for multi-project applications

78. ASSIST allows applicants to… 78 Use existing eRA Commons and Grants.gov accounts Pre-populate data from eRA Commons profiles Control application access Have multiple users within and outside the applicant organization work concurrently Check application against Grants.gov and NIH business rules before submitting Preview/print NIH application image before submitting Track Grants.gov and eRA Commons submission status

79. P42 Funding Opportunity Announcement 79 Announcement text indicates electronic submission is required. Apply for Grant Electronically button brings applicant to the ASSIST site.

80. 80 P42 Funding Opportunity Announcement 80 Types of components allowed for the FOA and available in ASSIST for application preparation. The Research Strategy page limits enforced in ASSIST for each component. Applicants will rely on the SF424 (R&R) Application Guide and the FOA text, especially Section IV. Application and Submission Information, when preparing their applications in ASSIST.

81. ASSIST Login 81 https://public.era.nih.gov/assist ASSIST leverages the eRA Commons accounts that most applicants already have. 81

82. Overall Component The Overall Component is added to the component navigation. The required forms are presented for the component. 82

83. Adding Additional Components Click Add New Component to continue building your application. Select from the drop- down list of component types available for the FOA. 83

84. Adding Components Applicants continue adding components to build out their application. Components are grouped by Component Type. Each component is given a random 3-digit, system- generated number for identification during application preparation. Components will be given sequential numbers in the assembled application image. 84

85. Projects & Cores – Additional Information Projects Research Strategy: Each project should also include a "Relation to Overall Center" statement. Administrative, Research Translation, Community Engagement, and Training Cores (Research Support Cores are optional) Research Strategy: each core will have a "Relation to Overall Center" statement; For CEC, include Community Engagement Statement in Research Strategy Other Attachments: Training Core will also have Diversity Recruitment and Retention Plan; Trainee List (required only for renewals) Other Attachments: Research Support Cores will also have Quality Assurance Statement 85 Refer to previous slides for instructions on using NRSA ASSIST Pages as well as additional attachment tables.

86. Resources SF424 (R&R) Application and Electronic Submission Information” webpage: – http://grants.nih.gov/grants/funding/424/index.htm http://grants.nih.gov/grants/funding/424/index.htm Applying Electronically to Multi-project Applications: – http://grants.nih.gov/grants/ElectronicReceipt/com_index.htm http://grants.nih.gov/grants/ElectronicReceipt/com_index.htm Need help with ASSIST? – http://grants.nih.gov/grants/ElectronicReceipt/faq_full.htm#about http://grants.nih.gov/grants/ElectronicReceipt/faq_full.htm#about 86 eRA Commons - https://commons.era.nih.gov/commons/index.jsphttps://commons.era.nih.gov/commons/index.jsp Registered PD/PIs can check assignment/contact information, review outcome, and other important information. eRA Commons Help Desk: Hours: Mon-Fri, 7AM-8PM EDT/EST Web: http://era.nih.gov/help/ Toll-free: 866-504- 9552. Phone: 301-402-7469. TTY: 301-451-5939.http://era.nih.gov/help/ eRA Commons - https://commons.era.nih.gov/commons/index.jsphttps://commons.era.nih.gov/commons/index.jsp Registered PD/PIs can check assignment/contact information, review outcome, and other important information. eRA Commons Help Desk: Hours: Mon-Fri, 7AM-8PM EDT/EST Web: http://era.nih.gov/help/ Toll-free: 866-504- 9552. Phone: 301-402-7469. TTY: 301-451-5939.http://era.nih.gov/help/

87. NIEHS Contacts: Program: William A. Suk suk@niehs.nih.gov, (919) 541-0797suk@niehs.nih.gov Heather Henry henryh@niehs.nih.gov, (919) 541-5330henryh@niehs.nih.gov Danielle Carlin danielle.carlin@nih.gov, (919) 541-1409danielle.carlin@nih.gov Grants Management: Lisa Edwards, archer@niehs.nih.gov, (919) 541-0751archer@niehs.nih.gov Michelle Victalino, victalinom@niehs.nih.gov, (919) 316-4666victalinom@niehs.nih.gov Scientific Review: Leroy Worth, worth@niehs.nih.gov, (919) 541-0670worth@niehs.nih.gov NIEHS Contacts: Program: William A. Suk suk@niehs.nih.gov, (919) 541-0797suk@niehs.nih.gov Heather Henry henryh@niehs.nih.gov, (919) 541-5330henryh@niehs.nih.gov Danielle Carlin danielle.carlin@nih.gov, (919) 541-1409danielle.carlin@nih.gov Grants Management: Lisa Edwards, archer@niehs.nih.gov, (919) 541-0751archer@niehs.nih.gov Michelle Victalino, victalinom@niehs.nih.gov, (919) 316-4666victalinom@niehs.nih.gov Scientific Review: Leroy Worth, worth@niehs.nih.gov, (919) 541-0670worth@niehs.nih.gov P42 Multi-Project Centers 87

88. Thank You! QUESTIONS?? Webinar Gurus Jean Balent, EPA TIFSD Justin Crane, MDB, Inc. Webinar Gurus Jean Balent, EPA TIFSD Justin Crane, MDB, Inc. SRP Team Bill Suk, Director Heather Henry Beth Anderson Danielle Carlin Michelle Heacock Rosemary Moody SRP Team Bill Suk, Director Heather Henry Beth Anderson Danielle Carlin Michelle Heacock Rosemary Moody NIEHS Staff Leroy Worth, SRO Lisa Archer Edwards, GMO Michelle Victalino, GMS NIEHS Staff Leroy Worth, SRO Lisa Archer Edwards, GMO Michelle Victalino, GMS Questions not covered during seminar will be answered off-line ASAP and posted on P42 Funding Opportunity Webpages: On SRP Website: http://www.niehs.nih.gov/research/supported /dert/cris/programs/srp/funding/rfa/index.cf m http://www.niehs.nih.gov/research/supported /dert/cris/programs/srp/funding/rfa/index.cf m Audio Archive will be available in approximately 4 weeks and are accessible from the above website. Questions not covered during seminar will be answered off-line ASAP and posted on P42 Funding Opportunity Webpages: On SRP Website: http://www.niehs.nih.gov/research/supported /dert/cris/programs/srp/funding/rfa/index.cf m http://www.niehs.nih.gov/research/supported /dert/cris/programs/srp/funding/rfa/index.cf m Audio Archive will be available in approximately 4 weeks and are accessible from the above website.