2. What is NESCent?

3. Inspired by the National Center for Ecological Analysis and Synthesis What is NESCent?

4. Downtown Durham, North Carolina National Evolutionary Synthesis Center

5. Consortium of 3 Research Triangle Universities Director Kathleen Smith DUKE Associate Directors Cliff Cunningham DUKEResearch and Development Greg GibsonNC StateEducation and Outreach Joel KingsolverUNC Science and Synthesis Todd VisionUNC Science and Synthesis

6. The In-House Community 15 Post-Doctoral Fellows 5 Sabbatical Faculty 3 Triangle Faculty (on teaching leaves)

7. Synthesis Working Groups (NCEAS-Style) 12 people, meet several times Assumption … the data is out there! Meetings to Catalyze and Achieve Synthesis

8. “Catalysis Meetings” 30 people around a central theme Lead to Grand Scale Research Collaborations Meetings to Catalyze and Achieve Synthesis

9. What is Synthesis?

10. Who is Occupying Real Estate in the Informatics Universe (and doing it well) Jump-Starting Evolutionary Databases Find “homes” for all data associated with submitted evolutionary papers

11. Genotype Phenotype Vertical Integration (lots of data on single species) Horizontal Integration (smaller amounts of data for many individuals and species) Genomic Sequences Genomic Maps Quantitative Trait loci Gene Expression: Microarrays Gene Expression: In-situ Images Mutation Phenotypes 2D Images Sequences From Many Individuals Specimen Collection Data, GIS Phylogenetic Relationships Quantitative Morphometric Behavioral Matrix-Coded Morphological Behavioral Specimen and Character Images GENBANK Generic Model Systems (GMOD) Assembling Tree of Life MorphBank MorphoBank Digi-Morph TreeBase (GBIF) BarCode of Life DataBase (BOLD) Population Genetic Database PEET Taxonomic Databases CHRONOS PaleoBiology Database Taxonomic Name Databases VegBank FlyBase, TAIR

12. Find “homes” for all data associated with submitted evolutionary papers Jump-Starting Evolutionary Databases

13. Each with Unique Challenges Inhibiting Data Population Foster “Nascent” DataBases (Controlled Ontologies) MorphBank/ MorphBank Proliferation/ Confusion

14. MorphBank/MorphoBank Summit: Neutral Site, LSID’s, Inter-operability Foster “Nascent” DataBases (Controlled Ontologies) MorphBank/ MorphBank Proliferation/ Confusion

15. Each with Unique Challenges Inhibiting Data Population Foster “Nascent” DataBases (Controlled Ontologies) Population Genetic DataBase Coordinating Data Submission

16. Data Submission Tools for Multiple Databases Foster “Nascent” DataBases (Controlled Ontologies) Population Genetic DataBase Coordinating Data Submission

17. Each with Unique Challenges Inhibiting Data Population Foster “Nascent” DataBases (Controlled Ontologies) Etho-Source Ontology-Written Need Programmer!

18. Wouldn’t it be great if all communities did this? Foster “Nascent” DataBases (Controlled Ontologies) Etho-Source Ontology-Written Need Programmer!

19. Find “homes” for all data associated with submitted evolutionary papers Establish an evolutionary data registry (building on the ecological data registry) Jump-Starting Evolutionary Databases

20. Data Centers Meta-Data Registry LSID’s to follow data to final “home” Wall of China Model-1

21. Facilitate Evolutionary Model Systems (GMOD) INTEGRATE TAXONOMIC AND MODEL SYSTEMS ONTOLOGIES! Wall of China Model-2

22. Targeted Sabbaticals and Working Groups INTEGRATE TAXONOMIC AND MODEL SYSTEMS ONTOLOGIES! Wall of China Model-2 Quentin Cronk Todd Vision Lincoln Stein Paula Mabee CTOL- Z-Fin

23. Software Integration W. Maddison An “Economy” of Service Oriented Providers

24. Genotype Phenotype Vertical Integration (lots of data on single species) Horizontal Integration (smaller amounts of data for many individuals and species) Genomic Sequences Genomic Maps Quantitative Trait loci Gene Expression: Microarrays Gene Expression: In-situ Images Mutation Phenotypes 2D Images Sequences From Many Individuals Specimen Collection Data, GIS Phylogenetic Relationships Quantitative Morphometric Behavioral Matrix-Coded Morphological Behavioral Specimen and Character Images GENBANK Generic Model Systems (GMOD) Assembling Tree of Life MorphBank MorphoBank Digi-Morph TreeBase (GBIF) BarCode of Life DataBase (BOLD) Population Genetic Database PEET Taxonomic Databases CHRONOS PaleoBiology Database Taxonomic Name Databases VegBank FlyBase, TAIR