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Enzymes Metabolism Reactions in your body What are Enzymes? Protein catalyst Act on substrates (reactants) End in ASE – Ex. Lactase digest lactose HOW?

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Presentation on theme: "Enzymes Metabolism Reactions in your body What are Enzymes? Protein catalyst Act on substrates (reactants) End in ASE – Ex. Lactase digest lactose HOW?"— Presentation transcript:

1

2 Enzymes

3 Metabolism Reactions in your body

4 What are Enzymes? Protein catalyst Act on substrates (reactants) End in ASE – Ex. Lactase digest lactose HOW?

5 Lower “Activation Energy”

6 6 Enzymes Free Energy Progress of the reaction Reactants Products Free energy of activation Without Enzyme With Enzyme

7 Enzyme Substrate Complex

8

9 Enzymes are Specific! Active Site Induced Fit

10 Enzymes can be REUSED Product is release

11 E1 E2 E3 E4 E5 E6 A  B  C  D  E  F  G A product can be used as a substrate for another enzyme

12 Factors Effecting Enzymatic Speed Temperature pH Substrate concentration Enzyme Concentration WILL DISCUSS these 2 WHEN WE GET BACK (IN OUR LAB)

13 Temperature Enzymes are PROTEIN Heat too high they can denature

14 pH Enzymes work best at an ‘optimal’ pH Proteins  can denature

15 Substrate Concentration The more substrate the more reaction Once all of the enzymes are being used the reaction cannot increase

16 Enzyme Concentration Control by phosphorylation Activate  Add Phosphate (energy from ATP)

17 Enzyme Inhibition Noncompetitive Competitive

18 Feedback Inhibition Activity of enzyme can be regulated by its end product

19 Enzyme Cofactors Help enzymes function – Inorganic Copper, Zinc, Iron – Organic- Coenzymes Vitamins

20 Pellagra

21 Scurvy


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