Presentation on theme: "Chapter 15 Enzyme Specificity and Regulation. 15.1 Specificity Is the Result of Molecular Recognition 15.1.1 Enzyme Specificity Structural specificity."— Presentation transcript:
Chapter 15 Enzyme Specificity and Regulation
15.1 Specificity Is the Result of Molecular Recognition Enzyme Specificity Structural specificity Stereospecificity
Hypothesis of Enzyme Action the “lock and key” hypothesis the “induced fit” hypothesis
Active Site of Enzyme The specific site on the enzyme where substrate binds and catalysis occurs is called the active site.
15.2 Allosteric Regulation Feedback inhibition (or regulation) A B C D Z E1 E2 E3 En A B C D Y E Z E1 E2 E3 E4En E3* E4*En*
Allosteric activator Allosteric inhibitor CO 2 + Glu + ATP CTP N-carbamoylaspartate Asp ATCase Carbamoyl phosphate Activation Inhibition