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Neurocysticercosis Jenna Sawafta Infectious Diseases in the Developing World Fall 2012.

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Presentation on theme: "Neurocysticercosis Jenna Sawafta Infectious Diseases in the Developing World Fall 2012."— Presentation transcript:

1 Neurocysticercosis Jenna Sawafta Infectious Diseases in the Developing World Fall 2012

2 Neuro-Brain Cysticercosis is an infection due to ingestion of Taenia Solium

3 The most common parasitic disease of the nervous system It is also the main cause of epilepsy in developing countries

4 60-80% of people with the disease become epileptic

5 What does a brain with neurocysticercosis look like? Normal Brain Neurocysticerosis

6 A closer look… Brain Lesions

7 How is the disease transmitted?

8 NCC is spread by the fecal oral route

9 Transmission occurs when pathogens of one host are introduced to the oral cavity of another Egg Intermediate Host Definitive Host

10 Larval form of parasite found in intermediate host (Pig) Infection of definitive host via:  Uncooked meat  Contaminated meat Adult form of the parasite manifests in human Tapeworms lay new eggs in muscle tissue Development of the tapeworm in the brain

11 Most commonly transmitted through food contamination

12 Who does this affect?

13 2.5 million people world-wide are living with Taenia Solium

14 The most heavily affected countries are in Latin America

15 Non-endemic countries’ cases are rising because of travel to endemic regions and immigration.

16 How do we treat it?

17 The main antiparasitic drugs https://www.healthtap.com/#topics/get-rid-of-threadworms Praziquantal Albendazole

18 Clinical trials shows that Albendazole kills 60-85% of brain cysterci in 4 weeks

19 What are we doing about it?

20  Improving sanitation  Modernizing swine husbandry  Developing detection technology for tapeworms

21 Works Consulted DeGiorgio, Christopher. "Neurocysticercosis." National Center for Biotechnology. US Library of Medicine, Web. 5 Nov "Examples of Common Cestodes." SRG General Pathology. University of Cambridge, n.d. Web. 06 Nov "Neurocysticercosis: Radiologic-Pathologic Correlation." RadioGraphics. Radiological Society of North America, n.d. Web. 10 Nov Zafaar, Mohammed. "Neurocysticercosis." MedScape. WebMed LLC, Web. 10 Nov { "@context": "http://schema.org", "@type": "ImageObject", "contentUrl": "http://images.slideplayer.com/3414946/12/slides/slide_20.jpg", "name": "Works Consulted DeGiorgio, Christopher. Neurocysticercosis. National Center for Biotechnology.", "description": "US Library of Medicine, 4 2004. Web. 5 Nov 2012.. Examples of Common Cestodes. SRG General Pathology. University of Cambridge, n.d. Web. 06 Nov 2012.. Neurocysticercosis: Radiologic-Pathologic Correlation. RadioGraphics. Radiological Society of North America, n.d. Web. 10 Nov 2012.. Zafaar, Mohammed. Neurocysticercosis. MedScape. WebMed LLC, 07 2011. Web. 10 Nov 2012.

22 Thank you!


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