1. The 2nd generation of Fractional Tx. With CIS-F1

2. What is LASER ? L : Light A : Amplification S : by Stimulated
L : Light
A : Amplification
S : by Stimulated
E : Emission
R : of Radiation

3. Diagram of a laser

4. Diagram of a laser

5. What makes laser different from other light Sources?
■ Monochromaticity
■ Coherence : the waves are in phase in time
and space.
■ Collimation

6. Laser and Tissue Interaction: Laser targets chromophore
For effective use of laser,
practitioners
must understand
‘Laser tissue interaction ’

7. Laser and Tissue Interaction: Laser targets chromophore
Typical chromophores
(chromophores’ absorbing laser in tissue):
Water (Chromophore of CIS-F1)
Hemoglobin and Oxy-hemoglobin
Melanin (including Hair)

8. Laser and Tissue Interaction
Laser interacts with tissue by absorption, scatter and/or transmission.
Grothus Draper Law : Laser application of tissue is based on the absorption.
Absorption
Transmission
Scatter
Reflection : 4-7% on skin surface
Refraction X V
“Laser light must be perpendicular with skin surface to minimize refraction”
Without incident angle
“No Absorption No Effect”

9. Laser Tissue Absorption Spectrum
532 nm (KTP)
585 nm (Pulsed Dye)
2940 nm (Er:YAG)
10,600 nm (CO2)
200
1000
5000
0.1 1 10
100
20000 Hb
HbO2
1550 nm (Er:Glass)

10. 3 Skin Layers

11. Laser and Tissue Interaction
Vaporization (>100 ºC)
Necrosis & Coagulation
(58-85 ºC)
Protein Denaturation
(> 60 ºC)
Photobiomodulation
(< 40 ºC)
LASER
Ablative Laser (CIS-F1)
Benefit
Injury

12. Laser and Tissue Interaction
Fractional irradiation
Fractional Tx. delivers
multiful micro-beams,
which hits the surface
of skin in a
fractionated manner
and allows for fast
healing by intact
surrounding healthy
Tissues.
Benefit

13. Laser and Tissue Interaction
Cytokine GF

14. Skin Tissue Interaction(CIS-F1)
10mJ, Moving mode
(50mm tip)
Depth: 230㎛ Width: 80 ㎛
** Slides of porcine skin
250mJ, Stamp mode
(50mm tip)
Depth: 1800㎛ Width: 150 ㎛
200mJ, Stamp mode
(100mm tip)
Depth: 1350㎛ Width: 200 ㎛

15. Selective Photothermolysis
Laser Light
Absorbed Target
Non absorbed target
*Temperature in the absorbed target will rise.

16. Termal Relaxation Time(TRT)
Small Blood Vessels are Typically <450 us
Melanosome is Typically <10ns to 100 ns

17. Comparison CIS-F1 Sellas-evo (10600㎛ fractional) (1550㎛ fractional)
CIS-F1
(10600㎛ fractional)
Sellas-evo
(1550㎛ fractional)
Ablative approach
Excellent in skin resurfacing
More effective on single Tx.
Require less than 3 Tx.
Combination enhancement
Prone to surface of skin Tx.
(face lift effect)
Non-ablative approach
Excellent in skin rejuvenation
Minimal downtime
Require less than 5 Tx.
Combination enhancement
Prone to dermis Tx.
(face volume up effect)

18. Keratinized outer layer (enhance absorption of topicals)
-Termal peeling. -How it works.
Structural change in
Keratinized outer layer
(enhance absorption of
topicals)
Biomodulation < 40˚C
(Activity of cytokine )
Stimulation of functional
cells (Cytokine,GF…)

19. CIS-F1 ▪ Specification www.sellaslaser.com Laser source RF CO2 Laser
Wavelength
10600nm
Operation mode
Stamping / Moving (Scanning)
Pulse energy
Stamp: 1-250mJ (Depth: 0.2~1.5mm)
Moving: 1-50mJ
Pattern size
Handpiece diameter 30mm tip
(microbeam dia. 150㎛)
Interface
Touch Screen
Weight
30kg
Dimension
40(W)x55(D)*90(H)cm

20. CIS-F1 Tip length (Focal length) 50mm 100mm Surgical tip Microbeam
Size
80㎛
120㎛
Power
Higher than 100mm tip applied
Lower than 50mm tip applied
Application
Deep penetration
(Deep scar)
Skin resurfacing
Incision, Cutting,
Nevus removal

21. CIS-F1

22. CIS-F1
User mode - easy to pick up the preset protocol

23. Tailoring the treatment zone
▪ Tailoring the treatment zone by drawing on canvas (X-Y scanner).
▪ Customized design is allowed for intensive treatment without excessive damage to
surrounding tissues.
Tailoring the spot pattern

24. Regular forms [ 16 standard regular forms] [ Max. 250mJ per micro dot]
[ 16 standard regular forms]
[ Max. 250mJ per micro dot]

25.
Cooling and topical anesthesia before “ high energy” procedures
30% lidocaine gel is applied on face; occlude for mins with BioMask

26. Terminology of Laser www.sellaslaser.com Dr. Gabriel Serrano, Spain
Immediate redness after Sellas laser

27. Terminology of Laser www.sellaslaser.com Stamping mode
Dr. Gabriel Serrano, Spain

28. Terminology of Laser www.sellaslaser.com Moving mode
Dr. Gabriel Serrano, Spain

29. Post-Care Treatment www.sellaslaser.com
Factors: Moisturizing / Anti-inflammatory / Revitalization / Sunscreen
Sunscreen above SPF 50
Vitamin C
Retinol at night
EGF, bFGF, Amino acid, Mineral, Co-enzymes, Necleonic acid
Copper peptide, Glyco-protein
1. Fast recovery against PIH after laser treatment (Whitening)
2. Improving skin tone and firmness (tightening).
3. Anti-aging restructuring of skin tissue
4. Post-trauma skin repair

30. Immediate care & First week after treatment
Post-Care Treatment
Post CIS-F1 treatment:
Immediate care & First week after treatment
C- Vit serum / Lotion + Factor G Lotion + Moisturizing pack
Sun screen
Away from excessive heat stimulus such as sauna, hot spa

31. Post-Care Treatment [Medical examination and treatment after 1 week
[Medical examination and treatment after 1 week
Restart skin care at home
Skin Healing or tighten mask as for cosmetic care (propymask, Biomask)
[Post CIS-F1 treatment]: Second week after treatment
Return to regular skin care: C-Vit Lotion + Factor G lotion (scars)
RetiseS / Fillderma System (aging), C-Vit
DaeSeS (DMAE) for flaccidity
Kojic acid / Alfa lipoic / arbutin (bleaching)
JuveSeS Teens / SaliSeS(acne)
[Medical examination and treatment after 2 weeks]: Combine treatments
Start aesthetic treatment with chemical peel, IPL, RF, Microdermabrasion, electroporation for
complementary approach (Antiaging, Whitening, Tightening)
[Second visit for CIS-F1 treatment after 4 weeks]

32. Contraindication for Sellas
Renal failure
2. Herpes simplex
3. Acute infection
4.Post thermal injury

33. Fast high density delivery
Advantages
Fast high density delivery
Able to tailor stamping shape
according to lesional shape
Thermal peeling
Only Sellas can represent “True” 2nd generation fractional laser!

34. PHOTOS (BEFORE/AFTER)
Terminology of Laser
PHOTOS (BEFORE/AFTER)

35. Skin Photo Gallery www.sellaslaser.com Patient age: 28 (Skin type: IV)
After 3 Tx

36. Skin Photo Gallery www.sellaslaser.com Patient age: 27 (Skin type: IV)
After 3 Tx

37. Skin Photo Gallery www.sellaslaser.com Patient age: 27 (Skin type: IV)
After 3 Tx

38. Skin Photo Gallery www.sellaslaser.com Patient age: 29 (Skin type: IV)
After 5 Tx

39. Skin Photo Gallery www.sellaslaser.com Patient age: 32 (Skin type: IV)
After 3 Tx

40. Skin Photo Gallery www.sellaslaser.com Patient age: 32 (Skin type: IV)
After 3 Tx
Patient age: 46 (Skin type: IV)
After 3 Tx

41. Skin Photo Gallery www.sellaslaser.com Patient age: 25 (Skin type: IV)
After 3 Tx

42. The 2nd Generation of Fractional Ablative Tx. With CIS-F1
Thank you.
The 2nd Generation of Fractional Ablative Tx. With CIS-F1