Presentation on theme: "Transport of gases Presents to you by ABOUT DISEASE.CO TEAM."— Presentation transcript:
Transport of gases Presents to you by ABOUT DISEASE.CO TEAM
Transport of Oxygen 3% in dissolved form i. e. dissolved in plasma. 97% bound to Haemoglobin
O2 Transport as dissolved in plasma At Arterial Po 2 = 0.29 ml of O 2 dissolved in 100 ml of blood At Venous Po 2 = 0.12 ml of O2 dissolved in 100 ml of blood 0.17 ml of O2 is carried in dissolved state to tissue by each 100 ml of blood
O2 transport as bound to Hb 1gm Hb can carry = 1.39 ml of O2. But due to impurities like met Hb 1gm Hb carries 1.34 ml of O2 15 gms will carry 1.34 x 15 = ml of O2 This happens at or more than 250 mmHg when Hb is 100% saturated. At arterial PO 2 only 97% of Hb is saturated
O2 transport as bound to Hb At arterial PO ml of O2 is bound to Hb. At venous PO ml of O2 is bound to Hb. 5 ml of O2 is transported as bound form from lungs to tissues by each 100 ml of blood.
O 2 Hb dissociation curve
A good index of the curve is the value P50 which is that partial pressure of oxygen at which one half of Hb occurs as oxyHb and one hallf as deoxyHb. Hb under physiological conditions has P50 value of 26 mm Hg. The higher P50 of Hb signifies its lesser affinity for Oxygen. Shifting of curve to right increases P50 value.
Effect of pH
Effect of Temperature
Bohr’s Effect Shifting of curve to right in response to increases in CO 2 or hydrogen ions