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Dr. Gautam Ghosh CPAP Workshop Dr. Gautam Ghosh Dr. Chandan Roy Dr. Ashok Modi Dr. Debjani Gupta Dr. Amit Roy.

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Presentation on theme: "Dr. Gautam Ghosh CPAP Workshop Dr. Gautam Ghosh Dr. Chandan Roy Dr. Ashok Modi Dr. Debjani Gupta Dr. Amit Roy."— Presentation transcript:

1 Dr. Gautam Ghosh CPAP Workshop Dr. Gautam Ghosh Dr. Chandan Roy Dr. Ashok Modi Dr. Debjani Gupta Dr. Amit Roy

2 Dr. Gautam Ghosh Definition CPAP : It is a modality of respiratory support in which increased pulmonary pressure is provided artificially during the expiratory phase of the respiration in a spontaneously breathing neonate. IPPV or IMV : Breathing is taken over completely by the machine & increased pulmonary pressure occurs during both inspiration & expiration.

3 Dr. Gautam Ghosh Historical review Poulton & Oxam 1936 Gregory et. Al 1971: first trial Agostino et.al 1973 : first RDS managed with CPAP. Bubble & Dual flow CPAP (Infant flow drive)

4 Dr. Gautam Ghosh Types of CPAP Oxygen hood Bubble CPAP & Dual flow CPAP machine Ventilator

5 Dr. Gautam Ghosh Physiological effects Organ System BenefitRisk Pulmona ry FRC / Static compliance / Pa02 IP Shunt/ WOB / PVR Splinting airway& diaphragm /surfactant +++ Air-leak syndrome / Decreased compliance at high pressure. CVS/ CNS CPP = MABP( ) --- ICP ( ) VR / CO ICT/ Renal /GIT ADH /Aldos. Urine / Gut distension

6 Dr. Gautam Ghosh Various Modes of CPAP MethodsAdvantagesDisadvantages ET TubeStable ++/ good control & ventilator access Invasive / Airway resistance ++ Nasal Prongs Easy / low resistance /easy feeding / non- invasive Septal erosion /nasal obstruction /abd. distension Nasophary ng. tube Non-invasive / easy feeding Leaks /pressure necrosis/abd. distension Mask CPAP mask Easiest applicationOral care difficult /leak / aspiration Head boxEasy applicationLeak /high flow 02 / access difficult

7 Dr. Gautam Ghosh Newer CPAP Bubble CPAP : vibration (high frequency?) / may be less CLD (?) Dual flow : Infant flow driver / fluidic flip mechanism / more stable PEEP control / failed nasal CPAP – try Dual flow CPAP— failed –try IMV

8 Dr. Gautam Ghosh Effect on Blood gases Oxygen : Improves due to increase in FRC through recruitment of atelectatic alveoli. CO2 : Decreases due to availability of greater surface area for gas exchange due to recruitment of alveoli. Excessive CPAP(> 7 cm) leads to over-distension of alveoli and CO2 retention. CPAP improves p O2, p CO2 change is secondary.

9 Dr. Gautam Ghosh CPAP Ranges RangesET TubeNasalComment Low3—44—5CPAP< 3 not useful Medium5—76—8Good range High Adverse effects common Fi O2 controlled from 0.2 to 1.0 with CPAP.

10 Dr. Gautam Ghosh Indications of CPAP Respiratory distress, moderate /severe: retraction or grunt. Recurrent apnea P aO2 0.6 ( O2 hood). Early : within 2 hrs of distress. Late ; after FiO2 requirement > 0.6

11 Dr. Gautam Ghosh Guidelines for CPAP Start with nasal CPAP of 5—6 cm & FiO2 0.4— 0.5 Increase CPAP by 1 cm if required Reach a CPAP of 8—9 cm. Now increase FiO2 in small steps of 0.05 up to 0.8 Clinical /ABG / SpO2 > 30min in each step Do not raise FiO2 before pressure : may remove hypoxic stimulus -- apnea Revert to IMV if not responding

12 Dr. Gautam Ghosh Weaning from CPAP Reduce nasal CPAP TO 8 cm Reduce FiO2 by 0.05 to 0.4 Reduce CPAP by 1 cm decrements Reach a level of CPAP 4cm / FiO2 0.4 Remove CPAP and replace a O2 hood.

13 Dr. Gautam Ghosh Optimum CPAP Comfortable baby / pink / normal BP No retraction / grunt No cyanosis / normal CRT CRT < 3 SEC SpO2 > % ABG : PaO / PaCO /p H Diagnosis ; Xray Chest in supine : Post. Intercostal space 7-8 (if > 8 : reduce PEEP / IF < 5 : raise PEEP)

14 Dr. Gautam Ghosh Failure of CPAP Retraction / Grunt ++ Apnea on CPAP PaO2 0.8 ( nasal CPAP >8cm) PaCO2 > 55 Baby not tolerating CPAP. Commonest cause : delay in starting

15 Dr. Gautam Ghosh Monitoring CPAP Clinical : comfort /RR,grunt,retraction /Cyanosis/HR, pulse / CRT,BP / Temp./ Abd.girth / Urine / CPAP machine Pulse Oximetry ; set alarm at 88%(L) & 95%(H). ABG : wait for min after each setting.

16 Dr. Gautam Ghosh Practical Points in CPAP Warm gases at 34—37* C & humidify. Gas flow (2 1/2 times minute ventilation) at 5-8 L/M minimum Look for nasal or oral blocks by secretion Oro-gastric suction is a must Stabilize the head with a cap and string Change CPAP circuit/prong every 3 days Asepsis. Sedation ?? Feed : oro-gastric 10 ml/kg EBM

17 Dr. Gautam Ghosh CPAP & RDS Prevent atelectasis/ preserve surfactant / avoid IMV Early better than late / no role in prophylactic CPAP INSURE : intubate / surfactant /extubate / CPAP with early signs( a/A o2 <0.36) Surfactant by CPAP ; future ??

18 Dr. Gautam Ghosh CPAP & Other disease CPAP after extubaion : Nasal better than ET tube CPAP / SNIPP (synchronised nasal intermittent positive pressure ventilation) MAS : better in atelectatic than over- inflated lung

19 Dr. Gautam Ghosh Complications of CPAP PAL : tends to occur when O2requirements are decreasing & compliance improving Excess PEEP : V /Q mismatch due to excess flow in under-ventilated lungs.

20 Dr. Gautam Ghosh Future With chance of cost of surfactant coming down in future, CPAP may be a better alternative in RDS. Noninvasive ventilation

21 Dr. Gautam Ghosh Case 1 30wks, Uncontrolled APH, 30 yrs, 4 th gravida, P 1+2, LUCS, 1 dose Dexa 12 hr before birth BVm with 100% O2for resuscitation, APGAR 5/1, 8/ gms female Cord blood PCV 56%, Sepsis screen –ve, gastric aspirate shake test –ve. 1hr: tachypnea, retractions, Spo2 82% Put on O2 hood (Fio2 0.5)

22 Dr. Gautam Ghosh ABG tree ABGCORD1 HR (hood) 6HR (CPAP) 14HR (IMV?) p H Pa CO PaO HCO SpO


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