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MBV2010/BIO2140 Colloquium, March 6. RULES Multiple choice Only one correct answer 30-60 seconds to answer No textbook, computer, mobile phone, please.

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Presentation on theme: "MBV2010/BIO2140 Colloquium, March 6. RULES Multiple choice Only one correct answer 30-60 seconds to answer No textbook, computer, mobile phone, please."— Presentation transcript:

1 MBV2010/BIO2140 Colloquium, March 6

2 RULES Multiple choice Only one correct answer seconds to answer No textbook, computer, mobile phone, please There will be a prize for the group with the most correct answers.

3 Which of the following statements is wrong? A Uracil is a pyrimidine base B Virus genomes can have a size of more than 2 million bp C Cytosine is often methylated in DNA D Some bacteriophages are retroviruses 1 ?

4 Which of the following statements is wrong? 1

5 Which of the following systems repairs DNA mismatches? A RBCD B MutSLH C UvrABC D DNA glycosylases 2

6 Which of the following systems repairs DNA mismatches? 2

7 DNA glycosylases are involved in A Base excision repair B Nucleotide excision repair C Direct repair of damaged bases D Repair of double strand breaks 3

8 DNA glycosylases are involved in 3

9 Which of the following DNA polymerases synthesizes DNA in a template-independent manner? A DNA polymerase I B DNA polymerase III C DNA polymerase IV D DNA polymerase ß 4

10 Which of the following DNA polymerases synthesizes DNA in a template-independent manner? 4

11 Most histone tail modifications occur on A Histone H2A B Histone H2B C Histone H3 D Histone H4 5

12 Most histone tail modifications occur on 5

13 Pairing of homologous chromosomes in meiosis is mediated by A Cohesins B Condensins C Homologous recombination D Cyclins 6

14 Pairing of homologous chromosomes in meiosis is mediated by 6

15 TRF2 is a protein that binds to A Centromeres B Replication forks C Telomeres D Origins of replication 7

16 TRF2 is a protein that binds to 7

17 Which of the following proteins resolves Holliday junctions? A RuvA B RuvB C RecA D Rad51c 8

18 Which of the following proteins resolves Holliday junctions? 8 Rad51c Rad51c and other eukaryotic proteins function like RuvC in E. coli

19 Which protein initiates homologous recombination in meiosis? A Spo11 B Dmc1 C MRX D Rad51 9

20 Which protein initiates homologous recombination in meiosis? 9

21 Spo11 is a A serine recombinase B transposase C type II topoisomerase D type I topoisomerase 10

22 Spo11 is a 10

23 What proteins are shown in this figure? A Xis and IHF B Xis and integrase C Integrase and IHF D none of the above 11

24 What proteins are shown in this figure? 11 IHF

25 The molecular weight of histones is between 12 A 11 – 21 kD B 6 – 12 kD C 20 – 25 kD D 28 – 35 kD

26 The molecular weight of histones is between 12

27 What are the most abundant transposons in the human genome? 13 A PolyA retrotransposons B DNA transposons C Endogenous retroviruses D LTR retrotransposons

28 What are the most abundant transposons in the human genome? 13

29 Which proteins are shown in this figure? 14 A RuvA (1) and RuvB (2) B RuvA (2) and RuvB (1) C RuvA (1) and RuvC (2) D RuvB (1) and RuvC (2) 1 2

30 Which proteins are shown in this figure?

31 The yellow protein in this figure is 15 A a DNA topoisomerase B a DNA polymerase C a DNA helicase D a primase

32 The yellow protein in this figure is 15

33 Insertion (IS) sequences are 16 A LINE retrotransposons B DNA transposons C LTR retrotransposons D SINE retrotransposons

34 Insertion (IS) sequences are 16

35 Which genome contains Ty transposons? 17 A Human B Drosophila C Yeast D E. coli

36 Which genome contains Ty transposons? 17

37 All transposons 18 A contain terminal repeats B contain a reverse transcriptase gene C contain at least one gene D are flanked by target site duplications

38 All transposons 18


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