Presentation on theme: "Lecture 10 Web: pollev.com/ucibio Text: To: 37607 Type in: 169964."— Presentation transcript:
Lecture 10 Web: pollev.com/ucibio Text: To: 37607 Type in: 169964
K m, V max, V 0 – What do they all mean? Parameters for enzyme action Rates and regulation!
1. K m [S] at which rate is ½ of V Max NOT ________ of enzyme for substrate High K m = ?
Physiological relevance of K M Coordination of metabolism: Glucose Energy Glucose Glycogen First step in both = Glc Glc-6-PO 4 Some tissues store, others need energy Convert Glc Glycogen only when [Glc] high?
2. V Max Compare rates of reaction at given [S] Some idea of efficacy of enzyme Regulation
3. k Cat Also an idea of rate #molecules converted per second Time per conversion
Enzyme regulation Structurally, how can we regulate enzymes?