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Sociedad Hondureña de Epilepsia Capítulo de la ILAE Dra. Claudia Amador Dr Marco Tulio Medina Dra. Sofia Dubon The Flag of Honduras.

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Presentation on theme: "Sociedad Hondureña de Epilepsia Capítulo de la ILAE Dra. Claudia Amador Dr Marco Tulio Medina Dra. Sofia Dubon The Flag of Honduras."— Presentation transcript:

1 Sociedad Hondureña de Epilepsia Capítulo de la ILAE Dra. Claudia Amador Dr Marco Tulio Medina Dra. Sofia Dubon The Flag of Honduras

2 Honduran Epilepsy Society 1. Dr. Claudia Amador * President 2. Dr. Heike Hesse Vice President 3. Prof. Marco T. Medina Past President 4. Dr. Reyna Duron Secretariat 5. Dr. Lazaro Molina Treasurer

3 HONDURAS Is a Central America Country with a Population of 8 millions

4 Health Care Three Health Systems in Honduras: 1.Ministry of Health 2.Social Security for state workers and others 3.Private Hospitals

5 Neurological Care There was one neurologist per 325,000 inhabitants in 1998 Neurological diseases account for approx. 20% of the medical consultations in hospitals

6 Formación de Neurólogos y Epileptólogos WFN

7 Epidemiología (Medina et al Epilepsia 2003, 2005)

8 TREATMENT

9 Status Epilepticus

10 Proyecto Demostrativo en Honduras: Brecha de Tratamiento

11 Community Intervention (Medina et al 2010, submitted)

12 Significant reduction of Epilepsy due to NCC (36% versus 13.9%)

13 Neuroepidemiology Studies

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16 The Salama Epilepsy Study ETIOLOGY OF EPILEPSY (n=90) Neurocysticercosis 37% Cryptogenic (occult) 30% Idiopathic 8% Perinatal brain damage 8 % Head trauma 3% CNS malformations 2% Vascular 2% Other neuroinfections 2% Other causes* 8% Other causes: inespecific calcified lesions, alcohol toxicity, inespectific intraventricular cyst, multifactorial.

17 Government involvement

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19 Epilepsy Surgery Program in Honduras

20 DiseaseJMECAE Phenotype Myoclonic, grand mal epilepsy, 1/3 with absences Pyknoleptic (2-200/day) absences of childhood PathologyMicrodysgenesis-Displaced and dystopic cells Normal GeneMyoclonin/ EFHC1 GABRB3 Transgenic mice KO mice replicate pathology and susceptibility KO mice replicate epilepsy Epilepsy Genes Epilepsy genes found in Honduras

21 Suzuki et al.Nature Genetics, 2004

22 Tanaka M, Olsen RW, Medina MT, et al Am J Hum Genet Jun;82(6):

23 Medina MT et al. Neurology 2008

24 Group of Patients Epilepsy (FUNDACION HONDURENA DE EPILEPSIA)

25 Publicaciones (Books and Journals

26 Latin American Epilepsy Academy (Academia Latino Americana de Epilepsia ALADE) Founded in Sao Paulo Feb. 27th, 2007


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