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A375A375R2 Vemurafenib (µM) BRAF (Full Length) p61-BRAF Isoform pMEK pERK Tubulin Supplementary Figure S A375-R4 NRas Q61KA375 Vemurafenib (µM) pMEK pS338-cRaf pERK Ras Tubulin B A
Supplementary Figure S2 Vehicle Vemurafenib LY Vemurafenib
Supplementary Figure S3 A375A375-RV2 pERK Tubulin Vemurafenib (µM)
Supplementary Figure S4 DMSO 1.5 M M M14 M14-R %G1= %S = %G2/M = %G1= %S = 2.73 %G2/M = %G1= %S = 3.81 %G2/M = %G1= %S = %G2/M = %Debris = %G1= %S = %G2/M = %Debris = %G1= %S = %G2/M = LY Relative Caspase 3 Activity (%) Log Concentration LY (nM) A375 A375-R1 M14 M14-R B A A375A375-RV1A375-RV2A375-R1A375A375-RV1A375-RV2A375-R1 Cyclin D1 siRNA Cyclin D1 ←Cyclin D2 Cleaved-PARP Tubulin C
Supplementary Table 1 A. B. CI simulations display synergism (CI 1) for the entire spectrum of effect levels (Fa) in the combination of NFV and BZ (right.
SKOV-3, 48h CaOV-3, 48h BG-1, 48h Concentration (µM) Viable cells (%) SW 43 SW IV-52s SW III-123 SW 43 + SW IV-52s SW 43 SW IV-52s SW III-123 SW 43 + SW.
Supplementary Figure 1: Co-treatment with SAHA and PLX4720 increases the level of a ~50kD fragment of PARP. Whole cell lysates from MM200 and Sk-Mel-28.
Supplementary Figure 1. Caspase 8 expression and activation and Fas expression in NSCLC and normal lung cell lines. A Western blot analysis of DR4 and.
Supplementary Figure 1. ER stress-induced secretion of mature IL-1β by THP-1 cells is dependent on the NLRP3 inflammasome. MSU 300 MockR shRNA :ScrambleNLRP3ASC.
Supplementary Figure 1 Supplemental Figure 1. Nogin siRNA potentiates BMP2-induced Smad-dependent BMP- signaling MDA-MB-231 breast cancer cells. MDA-MB-231/BREluc.
Fig. S1 HUVECs HDFNs HUVECs HDFNs Transwell CM Relative total length ** * control 200ng/ml400ng/ml TIMP-1 100ng/ml * ** GFP WT Mutant TIMP-1 TIMP-1 **
ScrMMP-1 Supplementary Fig. 1, Ganguly et al ScrMMP-3 ScrMMP-3MT1-MMP 100 m Relative Invasion Scr MMP m abc Scr Scr.
Mdm4 Mdm2 HAUSP 1: BT202: BT4744: BT5495: CAMA-1 6: DU4475 7: EVSA-T 8: HCC19379: Hs578T p53 p300 pRB ATM CBP p16 p21 p14ARF Tropomysosin Tubulin PUMA.
AP Biology Chapter 12: The Cell Cycle. One cell becoming two.
1 Chapter 29 Growth Factors Copyright © 2012, American Society for Neurochemistry. Published by Elsevier Inc. All rights reserved.
Facts and Figures Facts and Figures 2006 Facts and Figures 2006.
Supplementary Figure 1 >15 alleles Sens: 44% 1-Spec: 19% alleles Sens: 54% 1-Spec: 66% <12 alleles Sens:
Supplemental Figure 1 FLAG/Luc/#1 FLAG/Keap1/#1 A Vimentin FLAG/Luc/#1FLAG/Keap1/#1 B.
A b Supp. Figure 1: Anoikis-resistance of MDA-MB-231 is dependent on PI3Kγ (a) Cells were prevented from attaching for 48 hours in the presence of DMSO,
(a) Representative phase-contrast photomicrographs of adherent cells and mammospheres formed after 11 days; ×10 objective. The single cell suspension from.
Cancer and the Cell Cycle : An overview Ken Wu. Disclaimer This tutorial is a simple and conceptual guide to the cancer module and the cell cycle If there.
Supplementary Fig.1 Native expression Relative expression ratio vs. HKsRNAs a Relative expression ratio vs. pCMX DAOY Med8A Relative expression ratio vs.
Input IgG -LSD1 -HDAC1 Untreated SAHA LSD1 HDAC1 Input IgG -LSD1 -HDAC1 IP: (IB) Figure S1 Huang, Yi et al.
1 Chapter 43 - The Urine Concentrating Mechanism and Urea Transporters Copyright © 2013 Elsevier Inc. All rights reserved.
Results: Tables and Figures. Tables and Figures When to use what? Text: for simple results E.g. Seed production was higher for plants in the full-sun.
AAAAA WT In1m pAm ΔTIn1m ΔTpAm WT In1m pAm ΔTIn1m ΔTpAm Figure S1: Mutation of β-globin.
BANPAC Meeting June 20, 2012 Robyn Sakamoto, MPH, RD Rusty Hopewell, MS, RD ACPH – Nutrition Services.
3΄,4΄-Dimethoxythioflavone induces endothelium-dependent vasorelaxation through activation of EGF receptor Eun Jin Jang 1#, Young Mi Seok 2#, Jae In Lee.
Wild type 0 minutes 10 minutes 30 minutes ncsA Afu8g05010 (transcription factor) Fold increase.
A B Supplementary Figure 1 Supplementary Figure 1. Lenalidomide-sensitive wild-type (wt) and lenalidomide-resistant (R10R) ANBL-6 and U266 cells were infected.
INF GR / PS / 3 1 st meeting of the Informal Group on Pedestrian Safety September 4, OICA offices, Rue de Berri 4, Paris.
1 Introduction to Pharmacology Pawitra Pulbutr B.Pharm (Hon.), M.Sc in Pharm (Pharmacology) B.Pharm (Hon.), M.Sc in Pharm
Relative mRNA Levels Stat 1 WT1 5nM WT1 siRNAs Treatment Stat 1 Relative mRNA Levels nM TLR3 siRNA Treatment Supplemental Figure1. Stat 1 upregulation.
NEGpre-221 pre-222pre-221/222 NEG DMSO 100 nM Fulvestrant for 72h Figure S1. Cell morphology of MCF7 cells after treatment with fulvestrant, with or without.
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