We think you have liked this presentation. If you wish to download it, please recommend it to your friends in any social system. Share buttons are a little bit lower. Thank you!
Presentation is loading. Please wait.
Published byElise Rey
Modified about 1 year ago
Expression of Nuclear Receptors during Adipogenesis of 3T3-L1 Cells COUP-TFI COUP-TFII PPAR VDR GCNF ROR HNF4 LXR LXR RXR Nur77 REV-ERB REV-ERB
VDR and COUP-TFII Expression during Adipogenesis of 3T3-L1 Cells 0h 4h 8h 18h 1D 2D 3D 4D 5D 6D 7D 8D VDR COUP-TFII 0 6 12 18 24h 2d 3 4 5 6 7 8d Induction MediumDifferentiation Medium mRNA Fu et al., Mol. Endo. 19: 2437 (2005) COUP-TFII VDR
LXR α 0h 4h 8h 18h 1D 2D 3D 4D 5D 6D 7D 8D 0 6 12 18 24h 2d 3 4 5 6 7 8d Induction MediumDifferentiation Medium NR Expression during Adipogenesis of 3T3-L1 Cells (2) Fu et al., Mol. Endo. 19: 2437 (2005) Nur77 PPAR γ NUR77 LXR PPAR
0h 4h 8h 18h 1D 2D 3D 4D 5D 6D 7D 8D Actin COUP-TFI 0 6 12 18 24h 2d 3 4 5 6 7 8d Induction MediumDifferentiation Medium NR Expression during Adipogenesis of 3T3-L1 Cells GCNF Fu et al., Mol. Endo. 19: 2437 (2005) RXR α
Other Nuclear Receptors 0h 4h 8h 18h 1D 2D 3D 4D 5D 6D 7D 8D 0 2 4 8 18h 1 2 3 4 5 6 7 8 3T3-L1 cells Inducing MediumDjffer.Medium REV-ERB α REV-ERB β ROR α HNF4α LXR β
Interactions Between Vitamin D and Androgen Receptor Signaling in Prostate Cancer Cells Nancy L. Weigel, Ph.D. Baylor College of Medicine.
Supplementary Figure 1. Compararison of the expression of the genes within the 10q23 locus using either Troglitazone or Rosiglitazone as the PPAR agonist.
Project 3: Environmental PPARγ Agonist-Mediated Toxicity in the Developing Immune System Jennifer Schlezinger Environmental Health Boston University Superfund.
Appendix 1 Jeong et al. A. mPPAR (-)WYRosiGW CG269 1 M 1 M 1 M Relative reporter activity * ** B. hPPAR (-)WYRosiGW CG269.
N. Mitro et al. Nature advance online publication 24 December 2006 doi: /nature05449
Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell
Evidence for anti-inflammatory activity of statins and PPARα activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes.
The Application of DiverseSolutions (DVS) in the Establishment and Validation of a Target Class-Directed Chemistry Space Eugene L. Stewart*, Peter J. Brown.
Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer by Yun ‐ Yong Park, Kyounghyun Kim,
Hepatic Steatosis Chen-Yu Wang Nonalcoholic fatty liver disease (NAFLD) -Fatty liver (Steatosis) -Nonalcoholic steatohepatitis -Liver fibrosis.
1 Inhibition of PDCD6 Induces Cell Proliferation and Reduces Apoptosis in Human Epithelial Ovarian Cancer Cells Yan Huang, Xiaohua Wu Department of Gynecology,
01/27/2013 Brienna Larrick. Age-Related Changes in Skeletal Muscle Orange: Fat Infiltration Blue: High Density Muscle Green: Low Density Muscle The New.
Hormones Peptide HormonesSteroid Hormones. Examples of Lipophillic Hormones.
C1q g/L C2 g/L C3 g/L C4 g/L A. B. C.D. E. Supplementary Figure 1 - Middleton et al. NR Supplementary Figure 1. Complement concentrations in CLL patient.
Knight et al – Supplementary Table Supplemental Table 1: Cell line Densitometry AROSSIRT1 ARPE WI MCF10A HCT HCT116.
Manifestation of Novel Social Challenges of the European Union in the Teaching Material of Medical Biotechnology Master’s Programmes at the University.
Nardella et al. Supplementary Fig. 1 Murine Rheb wt Line 47 Line 50 Log gene expression (a.u.) ******* 200 bp Founders
Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007.
BioSci 2B - Environment and Human Health Bruce Blumberg –2113E McGaugh Hall – open office hours –phone check and noteboard.
Genetic Polymorphism (Asian) CYP2D6 SNP C188T (70%T) CYP2A6*4 (27%) CYP3A5*3 (72%) OATP2 SNP A388G (78%G) MRP1 SNP C218T (1%T), G2168A (2%A) MRP2 SNP G1249A.
Nuclear Receptor ( 核受体 ) Chromatin Immunoprecipitation Sequencing ( 染色质免疫共沉淀测序 )
Constitutive NF-κB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B- cell lymphomas by Lingchen Fu, Yen-Chiu Lin-Lee,
Molecular Carcinogenesis 43: He, G., S. Muga, P. Thuillier, R.A. Lubert, S.M. Fischer.
Lecture 10 Types of lineage mutants Lateral inhibition in C. elegans Induction in C. elegans.
Pyoderma gangrenosum: the hazards of polypharmacy in patients with impaired clearance mechanisms Ashley Fletcher, Colleen Reisz UMKC School of Medicine.
Different Strategies for Activating Transcription Factors.
Simple molecules <1nm IBM PowerPC 750 TM Microprocessor 7.56mm×8.799mm 6.35×10 6 transistors semiconductor nanocrystal (CdSe) 5nm
Signal Transduction Pathway Smorgasbord Ron Bose, MD PhD Biochemistry and Molecular Cell Biology Programs Washington University School of Medicine Molecular.
Control siRNA BRG1 siRNA PTEN – Akt – p-Akt – p-GSK-3 – Cyclin D1 – BRG1 – -actin – SW480 Supplemental data S1 Supplemental data S1. Effects of transduction.
Genetic factors associated with critical gene mutations/deletion may be responsible for 5-15% of non-cancer & cancer diseases Lifestyle/environment accounts.
INDUCTION OF AGROBACTERIUM 2-3h ADDITION OF AS 200 M final AGROBACTERIUM GROWTH in MG/L (Tingay et al., 1997) CENTRIFUGATION RESUSPENSION IN INOCULATION.
MRNA post-transcriptional regulation. synthesisfolding and modifications sortingdegradation DNA mRNA mRNA post-transcriptional modifications mRNA modifications.
Tyrosine kinase signalling (review) TGF signalling Notch signalling.
Phenotypic and Functional Changes Induced at the Clonal Level in Hematopoietic Stem Cells After 5-Fluorouracil Treatment by Troy D. Randall, and Irving.
Table S1. Primers for quantitative RT-PCR β-actinSense5'-ATCTGGCACCACACCTTC-3' Antisense5'-AGCCAGGTCCAGACGCA-3' CD36Sense5'-TGGTCAAGCCAGCTAGAAA-3' Antisense5'-CCCAGTCTCATTTAGCCAC-3'
We are working in Tier I with mechanisms Are mechanisms similar or dissimilar across phyla, species, classes, etc.? In other words – What is the phylogeny.
Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of Human Presenting author: Gireedhar Venkatachalam Gireedhar.
Christian Dani Team “Stem Cells and Differentiation” Faculty of Medicine, iBV, CNRS/Inserm, Nice, France Human Adipocyte Progenitors: Proliferation and.
ENVR 132/TOXC 142/BIOC142 Biochemical & Molecular Toxicology Induction of Metabolism by Toxicants Instructor: Stephen S. Ferguson, Ph.D.
1 Division of Endocrinology & Friedman Diabetes Institute, Department of Medicine, Beth -- Israel Medical Center & Albert Einstein College of Medicine,
Chemical Carcinogenesis: GENOTOXIC and NON-GENOTOXIC carcinogens.
Ca 2+ ‐ independent insulin exocytosis induced by α ‐ latrotoxin requires latrophilin, a G protein ‐ coupled receptor by Jochen Lang, Yuri Ushkaryov, Alfonso.
The use of Pan-PPAR Agonists for Treatment of Tauopathies and Huntington’s disease Inventor: Flint Beal, MD Chairman of Neurology and Neuroscience/Neurologist-in-Chief.
4.A.3 Cell Specialization Interactions between external stimuli and regulated gene expression result in specialization of cells, tissues and organs.
Cell Therapy in CV Disease: Newest Evidence. 2 Induction of pluripotent stem cells from human fibroblasts Study Source of fibroblasts Transcription factors.
Bioinformatics 3 V18 – Kinetic Motifs Mon, Jan 12, 2015.
Date of download: 6/2/2016 Copyright © The American College of Cardiology. All rights reserved. From: Omega-3 Fatty Acids and Cardiovascular Disease: Effects.
Lymphoma dissemination: the other face of lymphocyte homing by Steven T. Pals, David J. J. de Gorter, and Marcel Spaargaren Blood Volume 110(9):
Problems at the interface between statistics, biomathematics and bioinformatics Chris Glasbey Biomathematics & Statistics Scotland.
© 2017 SlidePlayer.com Inc. All rights reserved.