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Actual amount of substance supplied (removed) A = Q x ( Ca – Cv)
What determines flow (Q) Q = (Pa – Pv)/R
Q Low vascular resistance High vascular resistance (vasoconstriction
Measurement of Q
Blood flow velocity Q=10ml/s A= 2cm 2 10cm 2 1cm 2 V= 5cm/s 1cm/s 10cm/s V = Q / A abc
flow Vascular wall
Laminar high flow turbulent laminar velocity
Resistance to blood flow Rt = R1 + R2 + R3…………. Resistance in series 1/Rt = 1/R1 + 1/R2 + 1/R3…. Resistance in parallel SERIES PARALLEL R1R2R3 R1 R3 R2
x x x Redistribution in exercise x
Viskoaity ↑ při ↓↓ Q (anomalous blood viscosity)
What determines R ? Wall tension vasokonstriction vasodilatation
Pro trubici platí Laplace r
Wall tension Q pressure Critical closing pressure
Blood pressure Q = (Pa – Pv)/R
systolic diastolic Blood pressure (torr) Mean velocity cm/sec
Velocity of blood flow Q=10ml/s A= 2cm 2 10cm 2 1cm 2 V= 5cm/s 1cm/s 10cm/s V = Q / A abc
SYSTOLIC SV elasticity of aorta DIASTOLICR heart rate
Hemodynamics 1. Objectives Define resistance and understand the effects of adding resistance in series vs.in parallel in total resistance and flow. Describe.
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