1. Actual amount of substance supplied (removed) A = Q x ( Ca – Cv)

3. What determines flow (Q) Q = (Pa – Pv)/R

4. Q Low vascular resistance High vascular resistance (vasoconstriction

5. Measurement of Q

6. Electromagnetic flowmeter

7. Doppler effect

8. Fick principle

9. Blood flow velocity Q=10ml/s A= 2cm 2 10cm 2 1cm 2 V= 5cm/s 1cm/s 10cm/s V = Q / A abc

10. flow Vascular wall

11. murmur

12. Laminar high flow turbulent laminar velocity

13. Resistance to blood flow Rt = R1 + R2 + R3…………. Resistance in series 1/Rt = 1/R1 + 1/R2 + 1/R3…. Resistance in parallel SERIES PARALLEL R1R2R3 R1 R3 R2

15. x x x Redistribution in exercise x

17. Viskoaity ↑ při ↓↓ Q (anomalous blood viscosity)

18. What determines R ? Wall tension vasokonstriction vasodilatation

19. Pro trubici platí Laplace r

20. Wall tension Q pressure Critical closing pressure

21. RECRUITMENT

22. exercise

23. Blood pressure Q = (Pa – Pv)/R

24. systolic diastolic Blood pressure (torr) Mean velocity cm/sec

25. Velocity of blood flow Q=10ml/s A= 2cm 2 10cm 2 1cm 2 V= 5cm/s 1cm/s 10cm/s V = Q / A abc

27. SYSTOLIC SV elasticity of aorta DIASTOLICR heart rate

30. V P