# Actual amount of substance supplied (removed) A = Q x ( Ca – Cv)

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Actual amount of substance supplied (removed) A = Q x ( Ca – Cv)

What determines flow (Q) Q = (Pa – Pv)/R

Q Low vascular resistance High vascular resistance (vasoconstriction

Measurement of Q

Electromagnetic flowmeter

Doppler effect

Fick principle

Blood flow velocity Q=10ml/s A= 2cm 2 10cm 2 1cm 2 V= 5cm/s 1cm/s 10cm/s V = Q / A abc

flow Vascular wall

murmur

Laminar high flow turbulent laminar velocity

Resistance to blood flow Rt = R1 + R2 + R3…………. Resistance in series 1/Rt = 1/R1 + 1/R2 + 1/R3…. Resistance in parallel SERIES PARALLEL R1R2R3 R1 R3 R2

x x x Redistribution in exercise x

Viskoaity ↑ při ↓↓ Q (anomalous blood viscosity)

What determines R ? Wall tension vasokonstriction vasodilatation

Pro trubici platí Laplace r

Wall tension Q pressure Critical closing pressure

RECRUITMENT

exercise

Blood pressure Q = (Pa – Pv)/R

systolic diastolic Blood pressure (torr) Mean velocity cm/sec

Velocity of blood flow Q=10ml/s A= 2cm 2 10cm 2 1cm 2 V= 5cm/s 1cm/s 10cm/s V = Q / A abc

SYSTOLIC SV elasticity of aorta DIASTOLICR heart rate

V P

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