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National Bio and Agro-defense Facility K-State’s Biosecurity Research Institute Leaders’ Retreat 2011 James Guikema, KSU Associate Vice President.

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Presentation on theme: "National Bio and Agro-defense Facility K-State’s Biosecurity Research Institute Leaders’ Retreat 2011 James Guikema, KSU Associate Vice President."— Presentation transcript:

1 National Bio and Agro-defense Facility K-State’s Biosecurity Research Institute Leaders’ Retreat 2011 James Guikema, KSU Associate Vice President

2 National Bio and Agro-defense Facility K-State’s Biosecurity Research Institute NBAF … Coming to Manhattan! Not Just a Site … a Solution!

3 Plum Island An 840 acre island in the Long Island Sound Close enough to Long Island that deer swim back and forth

4 Plum Island Billed as: An island fortress for biosecurity 1789 – George Washington commissions 1789 – George Washington commissions first lighthouse 1897 – 130 acres for a harbor defense system 1897 – 130 acres for a harbor defense system 1899 – Fort Terry is established during the 1899 – Fort Terry is established during the Spanish American War – decommissioned after WW2

5 Plum Island Billed as: An island fortress for biosecurity 1954 – USDA acquires the island for research 1954 – USDA acquires the island for research

6 Billed as: An island fortress for biosecurity 1954 – USDA acquires the island from the Army 1954 – USDA acquires the island from the Army Responding to Foot & Mouth outbreaks Responding to Foot & Mouth outbreaks (US 1920’s, Mexico and Canada 1954) Established the Plum Island Animal Disease Established the Plum Island Animal Disease Research Center Plum Island

7 PIADRC Mission Detection technology for FAD Detection technology for FAD Development of FAD control strategies Development of FAD control strategies Risk assessment of FAD Risk assessment of FAD Diagnostics of suspected cases in US Diagnostics of suspected cases in US Testing of imported animals for FAD Testing of imported animals for FAD Production / maintaining vaccines & reagents Production / maintaining vaccines & reagents FAD training for animal health professional FAD training for animal health professional

8 Plum Island PIADRC current research FMD vaccines FMD vaccines Classic swine fever Classic swine fever Vesticular stomatitus virus Vesticular stomatitus virus Host / pathogen interactions Host / pathogen interactions Early immune enhancements against FAD Early immune enhancements against FAD TRANSFER FROM USDA TO DHS June, 2003 HS Presidential Directive 9

9 PIADRC current research PIADRC not able to meet the PD9 mission The facility is aging The facility is aging No BSL – 4 laboratories No BSL – 4 laboratories Decision to build the National Bio and Agro Defense Facility to meet the mission Plum Island

10 MISSION: To Protect U.S. Livestock from Foreign Animal Diseases (FADs) and Zoonotic (Contagious to People) FAD  To safeguard food animal health plus public health  To defend America’s food supply and ag economy  To replace the obsolete, 1950s Plum Island facility  To confront multiple emerging disease threats concurrently  To develop 21 st century vaccines/diagnostics/therapeutics What’s the Purpose of NBAF?

11  A 500,000 ft 2 federal biocontainment lab to study foreign animal diseases that could be transmitted to cattle, swine, and other livestock in the U.S.  Research, testing, development & evaluation for: Threat detection Vulnerability assessment Formulation of mitigation strategies  Development of disease countermeasures  Vaccine licensing support What Will It Provide?

12 As currently envisioned, NBAF will focus upon: Foot and Mouth Disease African Swine Fever Rift Valley Fever Contagious Bovine Pleuroneumonia Japanese Encephalitis Nipah Virus Hendra Virus What Will It Work On?

13 Former Senators Jim Talent (R-Missouri) and Bob Graham (D-Florida) ; Senators Susan Collins (R-Maine) and Joseph Lieberman (I-Connecticut) BIOTERRORISM: G REATEST WMD T HREAT W ORLDWIDE BIOTERRORISM: G REATEST WMD T HREAT W ORLDWIDE WMD Commission Assessments Graham/Talent Bipartisan Reports  2008: “The World at Risk” A biological attack is likely by 2013 A biological attack is likely by 2013  2009: “The Clock is Ticking!” A biological attack is more likely than a nuclear attack … and soon!!! A biological attack is more likely than a nuclear attack … and soon!!!  2010: “Prevention of WMD Proliferation and Terrorism” U.S. vigilance final “Report Card” U.S. vigilance final “Report Card” Bioterrorism readiness 2010 grade: Bioterrorism readiness 2010 grade: 11/21/09 What’s the Urgency? al Qaeda Animal Pathogen List Found by U.S. Troops in 2004 In a Cave in Afghanistan

14 Former Senators Jim Talent (R-Missouri) and Bob Graham (D-Florida) ; Senators Susan Collins (R-Maine) and Joseph Lieberman (I-Connecticut) BIOTERRORISM: G REATEST WMD T HREAT W ORLDWIDE BIOTERRORISM: G REATEST WMD T HREAT W ORLDWIDE WMD Commission Assessments Graham/Talent Bipartisan Reports  2008: “The World at Risk” A biological attack is likely by 2013 A biological attack is likely by 2013  2009: “The Clock is Ticking!” A biological attack is more likely than a nuclear attack … and soon!!! A biological attack is more likely than a nuclear attack … and soon!!!  2010: “Prevention of WMD Proliferation and Terrorism” U.S. vigilance final “Report Card” U.S. vigilance final “Report Card” Bioterrorism readiness 2010 grade: Bioterrorism readiness 2010 grade: 11/21/09 What’s the Urgency? S O, NBAF’ S CLOCK IS ALSO TICKING ! al Qaeda Animal Pathogen List Found by U.S. Troops in 2004 In a Cave in Afghanistan

15 Former Senators Jim Talent (R-Missouri) and Bob Graham (D-Florida) ; Senators Susan Collins (R-Maine) and Joseph Lieberman (I-Connecticut) BIOTERRORISM: G REATEST WMD T HREAT W ORLDWIDE BIOTERRORISM: G REATEST WMD T HREAT W ORLDWIDE WMD Commission Assessments Graham/Talent Bipartisan Reports  2008: “The World at Risk” A biological attack is likely by 2013 A biological attack is likely by 2013  2009: “The Clock is Ticking!” A biological attack is more likely than a nuclear attack … and soon!!! A biological attack is more likely than a nuclear attack … and soon!!!  2010: “Prevention of WMD Proliferation and Terrorism” U.S. vigilance final “Report Card” U.S. vigilance final “Report Card” Bioterrorism readiness 2010 grade: Bioterrorism readiness 2010 grade: 11/21/09 F What’s the Urgency? S O, NBAF’ S CLOCK IS ALSO TICKING ! al Qaeda Animal Pathogen List Found by U.S. Troops in 2004 In a Cave in Afghanistan

16 The timeline: March 2006 submission of Expressions of Interest KSU submits two – one for Manhattan and one for Leavenworth 29 total expressions of interest Who Competed?

17 The timeline: March 2006 submission of Expressions of Interest February 2007 – 17 sites are down-selected by DHS All 17 sites are visited by a site review team of USDA and DHS decision makers Who Competed?

18 The timeline: March 2006 submission of Expressions of Interest February 2007 – 17 sites are down-selected by DHS July 2007 – 5 finalists + Plum Island are further down-selected Who Competed?

19 The Finalists:  Manhattan, KS  San Antonio, TX  Athens, GA  Flora, MS  Butner, NC  Plum Island, NY March 2006 – 29 Expressions of Interest February 2007 – 17 Sites Down-Selected April/May 2007 – 17 Site Visits July 2007 – 5 Finalists + Plum Island Remain DHS scoping visits to each site – Environmental Impacts Studied 4 EIS public meetings at each site December 12, 2008 – Final EIS Published Who Competed?

20 The Finalists: With K-State Finishing #1  Manhattan, KS  San Antonio, TX  Athens, GA  Flora, MS  Butner, NC  Plum Island, NY Manhattan, Kansas: Record of Decision January 12, 2009 March 2006 – 29 Expressions of Interest February 2007 – 17 Sites Down-Selected April/May 2007 – 17 Site Visits July 2007 – 5 Finalists + Plum Island Remain – Environmental Impacts Studied December 12, 2008 – Final EIS Published Who Competed?

21 How Did Kansas Win NBAF? CRITERIAKSTXGAMSNCNY *Research* Ag/Vet Minimal Ag/Vet Ag/Vet Poultry No Ag/Vet Ag/Vet Minimal Ag/Vet Workforce A/C/O 1 Support Threat & Risk 15-Month EIS OVERALL # Acquisition/Construction/Operations Clearly meets criteria Partially meets criteria Fails to meet criteria Kansas: Unanimous #1 Of the DHS and USDA Scientific Steering Committee after a Three (3) Year Selection Process Finalists from 29 Submissions for 34 Sites after 17 Site Visits

22 Why Kansas? The Right Support  Kansas Congressional Delegation  Kansas Governor and Legislature  Kansas Governor’s NBAF Task Force  Kansas Board of Regents  Riley County Commission  Manhattan City Commission  Manhattan Area Chamber of Commerce  K-State Faculty Senate Leadership  K-State Classified Senate Leadership  K-State Student Governing Association  Kansas Agricultural Producer Groups  For details: Kansans

23 The Right Consortium Why Kansas? Fifteen Governors + countless “One Health” collaborators support NBAF in Kansas

24 Largest concentration of animal health companies in the world One-third of the Global Market! – Brakke Consulting 2006 – Why Kansas? The Right Expertise

25 Why Kansas? The Right Facility Biosecurity Research Institute No need to wait until 2014/15 Pat Roberts Hall BSL-3Ag BSL-3 Except BSL-4 Ready for the NBAF Mission in 2009

26 The Right Expertise Arthropod–Borne Animal Disease Research Laboratory/Unit  Moved to Manhattan in 2010; a unit within the USDA ARS Center for Grain and Animal Health Research (CGAHR)  Doing research on foreign & domestic insect vector–borne animal diseases BSL-3Ag research will be in the BRI Exotic Bluetongue; domestic disease Rift Valley Fever; a 3 rd NBAF disease  K-State’s Arthropod Genomics Center provides synergies with CGAHR/ABADRU What Does ABADRU Provide? To Complement the NBAF Mission ABADRU

27 The Right Research Center of Excellence for Emerging and Zoonotic Animal Diseases  DHS announced 02/19/10 that K-State will lead the DHS programs to: Develop new vaccines Improve rapid diagnostics Train in animal disease defense Support the DHS S&T Directorate  K-State CEEZAD: $12 million award; $2 million per year for 6 years  Texas A&M FAZD: $9 million award for modeling and information management What About CEEZAD? To Advance the NBAF Mission CEEZAD NBAF Mission Tasks

28 Why Kansas? The Right Location NanoScale CVM Pat Roberts Hall To A CCELERATE the NBAF Mission Via Public-Private Partnerships Westar NBAF Site (48-Acres) NanoScale Manhattan Innovation Center BRI Grain Science Purebred Beef Unit CVM K-State Research Park (25-Acres) KSU Foundation Property (14-Acres) K-State Equestrian Center Site Public Partnership Sites Private Development Sites +

29 The Requisite Site Work What’s Been Done Thus Far? To Facilitate NBAF Construction Marlatt Denison Some of the animal facilities that were on the NBAF site Contractors have relocated animal facilities and utilities on the NBAF site; land to transfer to DHS late September 2010.

30 The State-of- the-Art Plans What Will NBAF Look Like? To Tackle Imminent Disease Threats The NBAF site-specific design work is about 35% complete. The 500,000 ft 2 facility is anticipated to cost $600-$700 million.

31 The DHS Schedule What’s the Federal Timeline? To Begin NBAF Construction & Operations Site-Specific Risk Assessment Completed NAS Review of Risk Assessment Oct 2010 Start Central Utility Plant Construction FY 2011 Commence NBAF Lab Construction FY 2012 Complete Construction/Commissioning FY 2016 Initiate Transition from Plum Island 2016/17 NBAF to be fully operational 2017/18 T HAT ’ S A LONG TIME WHEN THE BIO - TERRORISM CLOCK IS ALREADY TICKING ! P AT R OBERTS H ALL

32 Kansas: The Only NBAF Choice Cost Share Quality of Life Public Support Talent Private Sector Partners Consequence Management Research Transition KANSAS: Not just a site … a National Security SOLUTION! KANSAS: Not just a site … a National Security SOLUTION! NBAF NBAF


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