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Wie Halbleitertechnologie die Medizintechnik revolutioniert

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Presentation on theme: "Wie Halbleitertechnologie die Medizintechnik revolutioniert"— Presentation transcript:

1 Wie Halbleitertechnologie die Medizintechnik revolutioniert
Design & Elektronik Developers' Forum: "Embedded Goes Medical" Leipzig, September 2009 Matthias Feulner Marketing Manager

2 Semiconductors Impact
Computing revolution Communications revolution Healthcare revolution Healthcare transformed Computing transformed Communications transformed 1980s 1990s 2000 and beyond

3 Making devices smaller…
2008 Bluetooth® + FM Single Chip GSM/GPRS Single Chip LoCosto™ 2000 Wireless LAN Single-chip GPS EDGE single-chip eCosto™ 1990

4 Chronic Disease Management Blood pressure monitor
…, more personal… 2.4GHz ISM (Zigbee/BT/ /ULP) Weight Management Chronic Disease Management GSM/GPRS Bluetooth / BLE Bluetooth / BLE Zigbee / Weight scale Blood pressure monitor Smart bandage Vital Signs Monitoring 800 MHz / 900 MHz ISM

5 … sensing and diagnosing
For in-hospital and out-of-hospital continuous wireless monitoring of vital signs and other physiological data directly off the body Body worn monitoring devices Chip + Sensor + printed battery in a low cost DISPOSABLE package Real time Intelligent Continuous Wireless ECG / Heart rate Temperature Activity / Motion Respiration Smart Bandage Location EVOLUTION REVOLUTION Wireless portable patient monitor Patient monitor

6 Diagnostic, patient monitoring and therapy Consumer medical devices
Innovation Across all Medical Segments Diagnostic, patient monitoring and therapy Consumer medical devices Medical imaging Medical instruments Uncomfortable Comfortable Doctor’s office + Patient’s home + Radiology center In the field Laboratory Innovation Digital thermometers Blood glucose monitor Blood pressure monitor Insulin pumps Heart rate monitors Audiology (digital hearing aids) ECG EEG Blood oxygen (pulse oximeter) Blood pressure Temperature Ventilation/ respiration Defibrillators Implantable devices Ultrasound CT MRI X-Ray Other imaging (nuclear, positron emission tomography) Laboratory equipment Dialysis machines Analytical instruments Surgical instruments Dental instruments

7 Addressing the Major Challenges
More Cost-Efficient More Portable Smaller & Lighter More Power-Efficient More Connected

8 Addressing the Major Challenges - Consumer Medical Case
More Cost-Efficient More Portable Smaller & Lighter More Power-Efficient More Connected

9 Consumer Medical Devices - Achieving Highest Level of Integration and Cost Efficiency
LCD Display MSP430FG439 LCD Driver MCU Op Amp Bio Sensor ADC Signal Processing DAC Op Amp VRef

10 Heart rate monitor based on SoC - Achieving Highest Level of Integration
Single chip SoC integration results in: over 50% size reduction (from 8+ chips to a single MSP430FG439 micro controller) ~50% cost reduction on semiconductors, circuit board and mechanical housing 10x increased battery life time, allowing lifetime sealed medical units with small coin cell batteries.

11 Addressing the Major Challenges - Portable Diagnostics & Therapy Case
More Cost-Efficient More Portable Smaller & Lighter More Power-Efficient More Connected

12 Portability for ECG Systems
Portable ECG images courtesy of Corscience

13 Traditional 8-Channel ECG System Solution
Integrated 8-Channel ECG System Solution Control Interface 24bit r S ADC Filter 24 - bit r S ADC Switching / Mux R(RA) Protect Amp Amp IA IA L(LA) Protect Amp Amp IA IA BT BT F(LL) Protect Amp Amp IA IA Integration results in: ~50% size reduction ~20% cost reduction ~20% power reduction Amp Amp C1(V1) Protect Amp Amp IA IA RTC RTC C2(V2) Protect Amp Amp Lead Selection Lead Selection IA IA m C MSP430 SD SD C3(V3) Protect Amp Amp IA IA CF CF C4(V4) Protect Amp Amp IA IA USB USB RS23 C5(V5) Protect Amp Amp IA IA 2 BUTTON I/F BUTTON I/F PSU PSU Monitor Monitor C6(V6) Disp Disp Protect Amp Amp Charge Charge Lamp Lamp r r Lead Off + + Calibration PACE DETECT Temp 3x Comparator Ref RLD Protect Amp Amp

14 Integrated ECG Solution Demonstrated
Integrated 16ch ADC ADS1258

15 Addressing the Major Challenges - Portable Ultrasound Case
More Cost-Efficient More Portable Smaller & Lighter More Power-Efficient More Connected

16 Bringing Ultrasound to the Point-of-Care
Military Mt. Everest Tsunami Images courtesy of Sonosite

17 Integration Steps for Portable Ultrasound
Analog signal chain Embedded Processing FET Driver Tx Buffer Amp Front End HV MUX Passive Transmit Beamformer Beamformer Control Unit DAC LPF Receive Beamformer T/R Switches Transducer Mid Amp Stage Analog Front End Amp + Filter Preprocessing Clocking Low Pass Filter LNA VCA PGA ADC Back End B Mode Processing Color/Power Doppler Processing Spectral Doppler Processing CW (analog) Beamformer ADC Scan Conversion Post Processing Ultrasound OS/UI Audio Amp Common Interfaces LPW RS232 USB 1394 802.11 Backlight Power Touchscreen Memory Interfaces MMC/SDIO IDE/ATA

18 Integration Steps for Portable Ultrasound
Analog signal chain Embedded processing FET Driver Tx Buffer Amp Front End High-PerformanceDSP Front end HV MUX Passive Transmit Beamformer Beamformer Control Unit DAC LPF Receive Beamformer T/R Switches Transducer Mid Amp Stage Analog Front End High- PerformanceDSP Mid Amp + Filter Preprocessing Clocking Low Pass Filter LNA VCA PGA ADC Back End B Mode Processing Color/Power Doppler Processing High- PerformanceDSP Back end Spectral Doppler Processing CW (analog) Beamformer ADC Scan Conversion Post Processing DSP SoC/Apps. processor Ultrasound OS/UI Audio Amp Common interfaces LPW RS232 USB 1394 802.11 Backlight Power Touchscreen Memory interfaces MMC/SDIO IDE/ATA

19 Ultrasound Receiver Front-End Integration Path
15mm 9mm AFE5805EVM

20 Portable Ultrasound Demonstrator Implemented 32 channels Tx & Rx on Analog Front End Board
Phantom Image Mimicking Tissue Mimicking Vessel Analog Front End Board AFE5805 TX734 DAC902 CDCE62005 DM6446 Reflectors Digital Processing Board

21 What are the Major Challenges
What are the Major Challenges? - Wireless Medical Sensors Case (BAN / AAL) More Cost-Efficient More Portable Smaller & Lighter More Power-Efficient More Connected

22 Goal: Reduce Wires for Patient Comfort
14-year old David during a sleep test Now go to sleep … Three electrodes on head Two electrodes on forehead One electrode next to each eye Two electrodes under mouth Two electrodes on each leg A pulse oximeter on the finger A chest belt for respiration monitor A breathing tube …all collected on the blue box From the blue box, a very thick cable ran to the computer that collected all the signals

23 Solution: Wireless Connected Vital Sensors
Hardware: Universal platform for the transfer of biosignals Telematik Thermometers Sphygmomanometers Smart Sensors The interconnection of new sensors with Peak-Flowmeter new sensor concepts By microsystems technology Software: Interface standards Scales Transfer of data via SMS Pulsoximeter continous Monitoring 3 channelsECG Courtesy of FZI Karlsruhe 23

24 Application in Experimental Monitoring Jacket
Continous measurement of Blood pressure change Activity sensor ECG Wireless communication (BlueTooth) MEDICA 2007 Electronics Courtesy of FZI Karlsruhe 24

25 Potential Wireless Standards
Wireless Connectivity for Medical applications Potential Wireless Standards Passive RFID Active RFID / Zigbee Bluetooth Low Energy Bluetooth IEEE b IEEE a/g IEEE n UWB Sub-1GHz ISM }

26 Wireless Connectivity for Medical applications
What is LE Bluetooth? CC2540 LE – Low Energy CC2540 Single mode device (BTLE only) Dual mode device (GTLE+Bluetooth BR/EDR) CC2540 Simplified version of Bluetooth optimized for low power Low average power – quick initialization of links Low peak current – suitable for coin cell usage

27 Wireless Connectivity for Medical applications
BT Classic vs. BT LE BT Classic (BR/EDR) Bluetooth Low Energy (BLE ) ISM bandwidth GHz GHz Star + Piconet Pure Star (no piconet) Topology Master send page, Slave scan Master scans, slave advertises Device Discovery Data rate 1, 2 or 3 Mbps 1 Mbps Range 5-10 m 5-10 m Modulation GFSK (BR), PSK (EDR) GFSK (index 0.5) Packet Formats Voice (SCO), Data (ACL) Data (ACL) Spec: -70 dbm BL6450: -95 dbm (BR) Sensitivity (BER=0.1%) Spec: -70 dbm BL6450: slightly better than -92 dbm Security Pseudo random XOR sequence AES-CCM (NIST approved) HCI Shared BR/EDR/ULP HCI (in dual-mode) Peak Current Consumption (peak) Init connection: 35mA for 10mS, ~10mA for <100mS Init connection: 17mA for 128uS CC2540 Average Power Consumption (Dual Mode) Data transfer once a minute: 70uA Paired – not connected uA Data transfer once a minute: 53uA Paired – not connected: uA Average Power Consumption (Single Mode) Data transfer once a minute: 70uA Paired – not connected: uA Data transfer once a minute: 7uA Paired – not connected: uA CC2540

28 BLE Enabled by CC2540 System-on-a-chip (SoC)
Wireless Connectivity for Medical applications BLE Enabled by CC2540 System-on-a-chip (SoC) Weight Management Chronic Disease Management Weight scale Blood pressure monitor Smart bandage Vital Signs Monitoring CC2540 BLE evaluation kit with USB dongle CC2540 BLE coin cell demo

29 Health Care Revolution


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