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1 HIGH IMPACT RESEARCH (HIR) UNIVERSITI MALAYA [2011-2015]
Mesyuarat Pemantauan Aktiviti High Impact Research Cycle 1 – Laporan Kemajuan 12 Bulan Cycle 2 – Laporan Kemajuan 6 Bulan 11 September 2012 Kementerian Pengajian Tinggi

2 QS WORLD RANKING 2012/2013

3 QS WORLD RANKING 2012/2013 Source : The Star 11/09/2012

4 MATLAMAT UNIVERSITI MALAYA
Meletakkan UM dalam ‘QS World Ranking’ 100 universiti terbaik pada tahun 2015 50 universiti terbaik pada tahun 2020

5 MATLAMAT PROJEK HIR (2011-2015)
Menjadikan Universiti Malaya antara 100 universiti terbaik dunia pada tahun 2015. Menerbitkan kertas Tier 1 Jurnal ISI/WoS yang berimpak tinggi. Menghasilkan lebih banyak bilangan paten pada setiap tahun. Membawa masuk Academic Icon untuk datang berkhidmat di UM. Mengambil pelajar Bright Sparks untuk meneruskan pengajian di UM.

6 Source : UM Library

7 Source : UM Library

8 kedudukan um dlm qs world rankinG
2004 (THES-QS) 2005 2006 2007 2008 2009 2010 2011 2012 89 169 192 246 230 180 207 167 156 Erroneous data submission

9 RESEARCH DATA (LAST 5-YEARS SCOPUS)
As at 31st August 2012 2012 2011 2010 2009 2008 2007 Papers 9,161 6,504 5,430 3,440 2,822 8922 Citations (excl. self-cites from 2011) 17,520 7,866 8,367 5,601 5,298 13,739 Citations per Paper: 1.9 1.2 1.5 1.6 Citations per Faculty: 4.5 3.0 3.2 2.1 2.76 6.9 Source : UM Library

10 LATAR BELAKANG PROJEK November 2010 – RM590,156,460 (140 projek)
3 & 4 Mei Hotel Equotorial Bangi- Bengkel Penilaian HIR Kitar 1. :84 projek (RM395,800,725) 22 November Hotel Marriot Putrajaya-Bengkel Penilaian HIR Kitar 2. :53 projek (RM108,368,721) 7, 8 & 9 Disember Aras 4, Canseleri UM-Makmal Pengurusan Nilai (VM Lab) anjuran Seksyen Pengurusan Nilai (SPN) : menilai skop dan kos peralatan HIR bagi 57 projek (RM71 juta). 24 Mei Aras 4, Canseleri UM-Bengkel Penilaian HIR Kitar 3 : 80 projek (RM165,023,729) – termasuk bidang Sains Sosial. Mesyuarat Kabinet 2010. 78 projek (RM352,905,185) telah diperaku oleh 17 penilai luar. 53 projek (RM108,368,721) telah diperaku oleh 6 orang penilai luar. Penjimatan sebanyak RM1.5juta menjadikan jumlah yang diperakukan RM69.5 juta. 66 projek (RM147,573,552) telah diperaku oleh 17 orang penilai luar. Hanya 75 projek (RM316,764,010) aktif dijalankan + selepas revised 68% *Baki sebanyak RM17,450,177 digunakan untuk kerja-kerja penyelenggaraan Peralatan HIR.

11 PERUNTUKAN HIR-MOHE Asal & Diluluskan KITAR 1 (2011) No Fakulti / PTj
(2012) KITAR 3 (2013) JUMLAH RM Bil. Projek 1 PERUBATAN 129,697,000 20 72,919,330 17 18,677,800 5 15,987,204 23 107,584,334 45 2 KEJURUTERAAN 200,000,000 62 52,837,469 65,108,120 27 13,750,226 11 131,695,815 61 3 SAINS 79,904,130 13 60,014,503 12 24,891,688 84,906,191 29 4 PERGIGIAN 28,287,330 22 13,194,753 8 15,092,351 5,542,880 33,829,984 24 SAINS KOMP. 27,268,000 9,126,490 6 3,201,200 780,000 13,107,690 15 CANSELERI 125,000,000 10 104,341,948 9 6,289,250 75,902,904 186,534,102 14 7 SAINS SOSIAL - 10,518,650 ALAM BINA 200,000 Secretariat (Baki Revised 68% ) 4,329,517 Penyelenggaraan Peralatan HIR (Sentral) 17,450,177 TOTAL : 590,156,460 140 316,764,010 75 108,368,721 53 165,023,729 66 194

12 Rumusan kitar 1 – laporan kemajuan 12 bulan
(dari Ogos 2011sehingga 15 Ogos 2012) No PTj No of Project Allocation Non Tier 1 ISI Tier 1 Bright Spark Academic Icon Patent Approved Spent % Proposed Achieved 1 Med 17 40,878,717.00 21,000,274.78 51.4 13 605 41 6.8% 164 3 1.8% 28 4 14.3% 38 0.0% 2 Eng 23 27,469,739.20 17,332,168.79 63.1 18 574 78 13.6% 137 15 10.9% 7.9% 139 6 4.3% Sci 12 34,009,211.80 25,148,526.78 73.9 77 635 107 16.9% 203 16 17.6% 99 10 10.1% Dent 8 7,043,569.00 5,263,541.13 74.7 101 2.0% 10.0% 5 IT 3,133,733.00 1,967,767.66 62.8 75 20.0% 29 6.9% 11 9.1% 34 2.9% Chan 9 68,210,033.00 45,165,786.33 66.2 731 74 110 7.3% 52.2% 95 4.2% TOTAL 180,745,003.00 115,878,065.47 64.1 132 2,721 317 11.7% 651 44 127 24 18.9% 410 21 5.1%

13 Rumusan kitar 2 – laporan kemajuan 6 bulan
(dari Ogos 2011sehingga 15 Ogos 2012) No PTj No of Project Allocation Non Tier 1 ISI Tier 1 Bright Spark Academic Icon Patent Approved Spent % Proposed Achieved 1 Med 5 14,355,450.00 502,069.81 3.5 59 0.0% 6 2 Eng 27 25,233,717.00 1,122,171.33 4.4 3 598 23 3.8% 69 7.2% 3.7% 64 1.6% Sci 0.00 - 4 Dent 13 5,965,934.00 532,359.92 8.9 118 100.0% IT 1,157,575.00 686,756.00 59.3 28 7.1% Chan 3,013,163.00 82,103.00 2.7 31 3.2% TOTAL 53 49,725,839.00 2,925,460.06 5.9 834 26 3.1% 77 7.8% 29 3.4% 1.4%

14 laporan kewangan (dari Ogos 2011sehingga 15 Ogos 2012) CYCLE
NO. OF PROJECTS ALLOCATION EXPENDITURE (RM) OPEX CAPEX TOTAL % CYCLE 1 (2011) 75 316,764,010.00 42,658,583.43 73,219,481.19 115,878,064.62 36.6 % CYCLE 2 (2012) 53 108,368,721.00 2,474,332.90 451,127.16 2,925,460.06 2.7 % CYCLE 3 (2013) 66 165,023,729.00 - 194 590,156,460.00 45,132,916.33 73,670,608.35 118,803,524.68 20.0 %

15 UM Publications in the following journals (2008-2012)
as of 30th August 2012 Journal / Year Impact Factor (JCR2010) 2008 2009 2010 2011 2012 Nature 36.104 Science 31.377 1 Lancet 33.633 3 2 New England Journal of Medicine 53.486 Cell 32.406 Plos Medicine 15.617 Proceedings of the National Academy of Sciences of the United States of America (PNAS) 9.771 Total Source : UM Library

16 SASARAN PENERBITAN BERIMPAK TINGGI
Impact Factor 2012 2013 2014 2015 Total Nature 36.104 1 2 4 5 12 Science 31.377 3 Lancet 33.633 PNAS 9.771 8 PLoS 15.617 19 TOTAL 7 13 21 45

17 TERIMA KASIH

18 HIGH IMPACT RESEARCH (HIR) UNIVERSITI MALAYA [2011-2015]
FACULTY OF MEDICINE CYCLE 1 – 12TH MONTH PROGRESS REPORT CYCLE 2 – 6TH MONTH PROGRESS REPORT 11th September 2012 Ministry of Higher Education

19 MEDICINE PROJECTS (as at 15th August 2012)
Cycle 1 No. Projects PI Overall Achievement Status 1. Mitigating HIV Epidemic Prof. Dr. Adeeba Kamarulzaman 51 – 75 % OS 2. Tropical Infectious Disease Prof. Dr. Sazaly Abu Bakar 3. Drug Development Prof. Dr. Mohd Rais Mustafa 4. Articular Diseases Prof. Dr. Tunku Kamarul Zaman 5. Pharmacogenomics Prof. Dr. Zahurin Mohamed 76 – 100 % 6. Molecular Infectious Disease Prof. Dr. Wong Kum Thong 7. Chemical Analysis Prof. Dr. Mustafa Ali Mohd 8. Neurology Research Prof. Dr. Tan Chong Tin % BS 9. Malaria Prof. Dr. Fong Mun Yik 10. Drug Addiction Treatment Prof. Dr. Mohamad Hussain Habil 11. Molecular Medicine Prof. Dr. Mary Anne Tan Jin Ai 12. Cancer Research Prof Dr. Hany Ariffin 13. Reactant Protein Prof Dr. Onn Hashim 14. Spatio-Temporal/Meta Analysis Prof Dr. Awang Bulgiba Awang Mahmud 15. Shared Facility Dr. Puteri Shafinaz Akmar 16. Beijing Genome Institute Prof. Dr. Fong Mun Yik 17. Anti-Neoplastic Drug Prof Dr. Chung Lip Yong * AS = ahead of schedule OS = on schedule BS = behind schedule

20 MEDICINE PROJECTS (as at 15th August 2012)
Cycle 2 No. Projects PI Overall Achievement Status 18. Parasitic Infections Dr. Lau Yee Ling 51 – 75 % OS 19. Eye Research Centre Prof. Dr. Visvaraja Subrayan 20. Dengue Hemorrhagic Fever Prof. Dr. Shamala Devi 21. 3T-MRI Prof Dr. Tunku Kamarul Zaman 26 – 50 % BS 22. Hypertensive Drugs Prof. Dr. Mohd Rais Mustafa * AS = ahead of schedule OS = on schedule BS = behind schedule

21 Spent / Commitment (RM)
BUDGET EXPENDITURES Cycle 1 No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX 1 6,026,778.00 2,377,852.00 1,151,874.00 3,529,726.00 58.6% 2 4,848,750.00 1,594,649.19 714,000.00 2,308,649.19 47.6% 3 845,800.00 508,451.16 104,544.00 612,995.16 72.5% 4 1,335,546.00 522,454.88 384,205.00 906,659.88 68.2% 5 1,250,840.00 886,065.26 - 70.8% 6 587,410.00 424,593.46 3,850.00 428,443.46 72.9% 7 1,505,900.00 56,902.46 1,100,000.00 1,156,902.46 76.8% 8 1,275,370.00 561,299.99 46,300.00 607,599.99 49.1% 9 448,900.00 183,824.80 45,000.00 228,824.80 51.0% 10 492,500.00 138,955.00 215,680.00 354,635.00 72.0% 11 1,074,500.00 432,406.00 82,000.00 514,406.00 47.9% 12 3,188,380.00 1,272,400.82 260,000.00 1,532,400.82 38.8%

22 Spent / Commitment (RM)
BUDGET EXPENDITURES Cycle 1 No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX 13 1,363,500.00 746,396.43 - 54.7% 14 787,250.00 322,802.92 48,942.00 371,744.92 47.2% 15 11,817,500.00 5,500,000.00 46.5% 16 2,604,800.00 939,221.38 113,865.00 1,053,086.38 36.1% 17 390,500.00 261,739.03 67.0% Total 40,878,717.00 11,230,014.78 9,770,260.00 21,000,274.78 51.4%

23 Spent / Commitment (RM) Spent / Commitment (RM)
BUDGET EXPENDITURES Cycle 2 No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX 18 1,134,300.00 288,975.00 25.5 19 1,064,000.00 6,897.85 35,224.00 42,121.85 4.0 20 306,850.00 44,055.00 43,000.00 87,055.00 24.9 21 11,623,250.00 0.00 22 227,050.00 83,917.96 37.0 Total 14,355,450.00 423,845.81 78,224.00 502,069.81 3.5 Overall No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX Total 55,234,167.00 11,653,860.59 9,848,484.00 21,502,344.59 38.4%

24 HUMAN CAPITAL DEVELOPMENT
No Category Local International TOTAL 1. RA 67 12 79 2. RA + Student i. Master Student 24 3 27 ii. PhD Student 8 11 3. Student 25 4. HIR-Post Doc * 1 2 5. Senior Researcher ** 137 20 157 * = fresh PhD holder ** = PhD with 5 years experiences

25 KPI ACHIEVEMENT Tier 1 (T1) Bright Spark (BS) Academic Icon (AI)
Tier 1 (T1) Bright Spark (BS) Academic Icon (AI) Patent (P) Total KPI Y1 Y2 Y3 Y4 Y5 T1 BS AI P Proposed 25 97 130 152 212 6 21 41 47 49 3 4 5 16 12 122 27 Actual 41    3   4   0  3

26 PANEL EVALUATION REPORT
Held on 27 August 2012 Progress achievement evaluation based on : 12th Months Progress Report for Cycle 1 – 17 projects (July 2011 – June 2012) 6th Months Progress Report for Cycle 2 – 5 projects (February 2012 – July 2012) Panel members - HIR Committee, Faculty of Medicine :- Professor Dato’ Mohd Amin Jalaludin Professor Dato’ Dr. Goh Khean Lee Professor Dr. Amru Nasrulhaq Boyce Professor Dr. Tunku Kamarul Zaman Tunku Zainol Abidin

27 PANEL EVALUATION REPORT
No Project Achievement General Comments Recommendation 1 Good Project is progressing well. Still early to determine output Continuation 2 Good progress. Output is acceptable and expecting more in next coming progress report 3 Excellent progress 4 Project progressing well on schedule 5 Good progress. 2 publications achieved. Expect good outcome of this study 6 Although output appears to be good, the progress of the project and the relevance of the output to the activity made is unclear. Report was poorly written and activities not clearly stated. Need to improve this in next progress report or may consider pinalizing PI on this output 7 Progressing well 8 Acceptable progress. Publication and work carried out currently does not fall under the title of the project. Need to clarify in next progress report 9 Good outcomes but project needs to improve on the aspect of expenditure 10 Acceptable Progressing and need to determine output in next progress report 11 Good progress and publications

28 PANEL EVALUATION REPORT
No Project Achievement General Comments Recommendation 12 Good Good progress and publications Continuation 13 Very good progress 14 Good progress and good output 15 Central facility development is progressing well 16 Project progressing, have 2 publications to date 17 Good progress 18 Very early progressing stage 19 Acceptable Project may slow progress. Committee extremely concerned and needs further monitoring. Title is too open with no clear objectives. Committee feels that the project may not be viable Request another report in 4 months 20 Still early in development stage. Project progressing 21 Project is in progress 22 Project still progressing

29 IMPACT TO SOCIETY 1. Puteri Shafinaz Akmar Abdul Rahman
All the high-end equipments purchased under this grant will be placed in Medical Biotechnology Laboratory which will act as one-stop centre for the researchers. These equipment will be opened for service to all the researchers from IPTAs and IPTS. 2. Mary Anne Tan Jin Ai Molecular investigation was applied to develop techniques which are rapid, sensitive and specific for the diagnosis of genetic disorders. Investigation was also carried out into cytotoxic and nutrigenomic properties of selected natural plant products. 3. Sazaly Abu Bakar Research findings which includes various tropical infectious agents survival mechanisms are aimed towards better early diagnosis and control measures of tropical infectious diseases, and this includes vaccination and drug development against the pathogens.

30 IMPACT TO SOCIETY 4. Mustafa Ali Mohd
The project will be able to help ensure the safety of the population in relation to long term exposure to the endocrine disrupting chemicals in environment and food. The government will benefit by taking early actions from the result of the study, either to avoid, or continue using the existing materials, or look for alternative chemicals for this purpose. 5. Mohd Rais Mustafa Discoveries of the mechanisms and cellular targets of natural compounds hold great values in pharmaceutical industry.  And provide the scientific basis for the efficacy or lack of it with regards to these natural remedies 6. Adeeba Kamarulzaman The projects within this research program will contribute to the prevention and control of HIV and tuberculosis in the community and incarcerated settings. The basic science and translational component of the research program will contribute towards better clinical management of HIV infected individuals

31

32 HIGH IMPACT RESEARCH (HIR) UNIVERSITI MALAYA [2011-2015]
FACULTY OF ENGINEERING CYCLE 1 – 12TH MONTH PROGRESS REPORT CYCLE 2 – 6TH MONTH PROGRESS REPORT 11th September 2012 Ministry of Higher Education

33 FACULTY OF ENGINEERING PROJECTS (as at 15th August 2012)
Cycle 1 No. Projects PI Overall Achievement Status 1. Precision Joining Technology Prof.Dr Mohd Hamdi Abd Shukor 76-100% OS 2. Synthesis Of Blast Resistant Structures Prof. Ir Dr.Mohd Zamin Jumaat 26-50% BS 3. Chemically and Electrochemically Generated Superoxide Ion in deep Eutectic Solvents and Ionic Liquids and their Application Prof. Dr. Mohd Ali Hashim 4. Study on the Impact of Solar Energy Penetration on National Power Grid and its Solutions Dr. Hazlie Bin Mokhlis 5. Design and Construction of early detection of Dengue Diagnostic Device Assoc. Prof. Dr. Fatimah Abu Bakar 6. Experimental Investigation of New Bioenergy sources for Biofuel from Tropical Biodiversity Dr. Chong Wen Tong 51-75% 7. Clean Diesel Technology For Military and Civilian Transport Vehicles Prof. Dr. Masjuki Hj. Hassan 8. Multiaxial fatigue of elastomeric materials in biofuel system Dr. Andri Andriyana 0-25% 9. 2 Micron Fiber laser and Nanowires Prof.Dr Sulaiman Wadi Harun 10. Biomechanical system for hard tissues of normal and disable subjects Assoc. Prof. Dr. Noor Azuan Abu Osman * AS = ahead of schedule OS = on schedule BS = behind schedule

34 No. Projects PI Overall Achievement Status 11. Biodiesel from pyrolytic Oil produced fom palm shell by hydrodeoxygenation process Prof Dr Wan Ashri Wan Daud 0-25% BS 12. Synthesis and development of novel nanocomposite silver for metamaterials at optical and microwave frequencies Dr Mohd Rafie Johan 51-75% OS 13. Sustainable treatment of wastewater from latex and rubber process industries by biosorption process Dr. Jaya Narayan Sahu 76-100% 14. Synthetic Prosthetic Socket through Stump-Liner Interfacial Stresses Measurement Assc. Prof. Dr. Noor Azuan Abu Osman 15. Automobiles fuel economy standards and label: implementation possibilities in Malaysia Dr. Chong Wen Tong 16. Human-Machine Interface via Brain Signals Applications Puan Norrima Mokhtar 17. Torque Ripple Reduction and Design Optimization of Voltage Vector Controlled PMSM Drives Supplied by Innovative Multilevel Inverters Prof. Dr. Saad Mekhilef 26-50% 18. Undivided Redox Flow Battery Reactor Employing Porous Flow through electrodes and Deep Eutectic Solvents Prof. Dr Mohd Ali Hashim 19. Characterization of the negative biased temperature instability (NBTI) impact on new-age deep- submicron devices to effectively predict system failure Assc. Prof Dr Norhayati Soin * AS = ahead of schedule OS = on schedule BS = behind schedule

35 Cycle 2 No. Projects PI Overall Achievement Status 20.
Production of hydrogen by hydrolysis of biomass Dr. Jaya Narayan Sahu 76-100% OS 21. Phase Change material (PCM) for energy storage system Dr. Hendrik Simon Cornellis Metselaar 26-50% BS 22. Hybrid Solar Energy Research suitable for Rural Electrification Prof. Dr. Hew Wooi Ping 51-75% 23. Hydrogen refueling station and dispenser control system Dr Mahidzal Dahari Cycle 2 No. Projects PI Overall Achievement Status 24. Applications of Solar Energy in Agricultural Sector Prof. Dr. Saad Mekhilef % BS 25. Development of an Advanced Model and Optimal Control System for Gas-Phase Olefin Polymerization in Fluidized-Bed Catalytic Reactor Prof. Ir. Dr. Mohd Azlan Hussain 26. Nano-mechanical Properties of Advanced Lead Free Solder for Microelectronic Packaging Prof. Dr. A.S.M.A Haseeb 27. Bovine Hydroxyapatite Derived Porous Bone Graft for Biomedical Applications Prof. Dr. Mohd Hamdi Abd Shukor * AS = ahead of schedule OS = on schedule BS = behind schedule

36 Prof. Dr. Nasarudin Rahim Dr. Judha Purbalaksono
Projects PI Overall Achievement Status 28. Reconstruction Of Artificial Prosthesis Limbs Prof. Dr. Imtiaz Chowdhury % BS 29. Fabrication and Characterisation of High Efficiency Green Technology Devices (Solar Cells and Thermoelectric Devices) Dr. Suhana Mohd Said 30. Oxy-fuel combustion technology: A new promising way to mitigate CO2, NOx, SO2 emissions simultaneously Dr. Brahim Si Ali 31. Sustainable Resource Conservation Approach to the End of Life of EEE (Electrical And Electronics Equipment) in the Context of Energy, Process and Carbon Offsetting: A Study for Malaysian Industry Assoc. Prof. Dr. Shamsuddin Ahmed 32. Campus Network Smart Grid System for Energy Security Prof. Dr. Nasarudin Rahim 33. Numerical Simulations and Experimental Investigations on the Multiaxial Fatigue and Cyclic Plastic Response of the Newly Developed Aluminum Alloy and FGM for Aerospace Structures Dr. Judha Purbalaksono 34. Coastal Protection Using Eco-Engineering Technologies Prof. Dr. Roslan Hashim 35. Integrated Production Planning and Decision Analysis Systems for SMEs Assoc. Prof. Dr. Siti Zawiah Md. Dawal 36. Strengthening Structural Elements for Load and Fatigue Prof. Ir. Dr. Mohd Zamin Jumaat * AS = ahead of schedule OS = on schedule BS = behind schedule

37 No. Projects PI Overall Achievement Status 37. Modification of Fenton Oxidation process for Treatment of Recalcitrant Wastewaters Assoc. Prof. Ir. Dr. Abdul Aziz Abdul Raman % BS 38. Custom Based Development of Bio and Chemical Reactors Using Advanced Fluid Dynamic Analysis 39. Powering Up Paralyzed Muscles Using Functional Electrical Stimulation (FES): An Advance in Rehabilitation Engineering Dr. Ahmad Khairi 40. Nano-fluids in Enhancing the performances of Heat Exchangers Assoc. Prof. Dr. Saidur Rahman 41. Exoskeleton robotics device for limb impairment support Mr. Norhafizan 42. Design of Image Quality Metric and Pattern Features for Multimedia Applications and Video Based Analysis Prof. Dr. Raveendran 43. Hybrid Solar Electrochemical and Bioelectrochemical Water Treatment Process Using Activated Carbon Prof. Dr. Mohd Kheiruddin Aroua 44. Regenerative Biomechanics Of Human Body Prof. Dr. Wan Abu Bakar 45. Corrosion and fouling mitigation for food industries via modification of heat exchanger Dr.Kazi Salim Newaz 46. Reconfiguration of Conduit Geometry for Heat Transfer Augmentation for Industrial Heat Exchangers/Heat Exchanging Equipment Dr. Ahmad Badaruddin Badry * AS = ahead of schedule OS = on schedule BS = behind schedule

38 * AS = ahead of schedule OS = on schedule BS = behind schedule No.
Projects PI Overall Achievement Status 47. Sustatainable Ocean Energy and Waterway Developments in the Straits of Malacca Assoc. Prof. Dr. Lam Wei Haur % BS 48. Study of Partial Discharge Characteristics within Voids in Dielectric Materials with Nanofillers Dr. Hazlee Azil Illias 49. Central Advanced Research Enabler Facility (CAREF) Assoc. Prof. Dr. Faisal Rafiq Mahamd Adikan 50. Physiological Control of an Implantable Rotary Blood Pump Dr. Lim Einly * AS = ahead of schedule OS = on schedule BS = behind schedule

39 BUDGET expenditures (as at 15th August 2012)
Cycle 1 No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX 1 1,686,728.00 403,845.73 704,929.40 1,108,775.13 65.74 2 919,840.00 251,542.00 154,000.00 405,542.00 44.09 3 1,128,288.00 572,579.18 81,868.00 654,447.18 58.00 4 632,425.00 138,180.00 399,500.00 537,680.00 85.02 5 650,811.75 250,504.63 103,282.00 353,786.63 54.36 6 726,180.00 369,197.81 50,450.00 419,647.81 57.79 7 3,590,982.00 359,836.86 2,883,620.00 3,243,456.86 90.32 8 837,200.00 103,390.00 386,000.00 489,390.00 58.46 9 655,010.00 152,000.00 280,000.00 432,000.00 65.95 10 2,026,082.00 556,569.30 594,955.00 1,151,524.30 56.84 11 1,094,100.00 118,321.68 471,776.00 590,097.68 53.93 12 661,300.00 97,418.11 380,000.00 477,418.11 76.02 13 590,150.00 85,500.00 88,258.00 173,758.00 29.44

40 Spent / Commitment (RM) Spent / Commitment (RM)
No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX 14 1,763,637.00 318,321.85 401,046.00 719,367.85 40.79 15 985,000.00 323,067.98 150,080.00 473,147.98 48.04 16 364,205.00 165,847.60 125,000.00 290,847.60 79.86 17 434,800.00 159,515.65 78,000.00 237,515.65 54.63 18 336,750.00 134,414.00 162,918.92 297,332.92 88.29 19 328,170.45 62,790.10 150,000.00 212,790.10 64.84 20 1,011,400.00 73,519.85 201,000.00 274,519.85 27.14 21 2,788,530.00 654,511.89 578,027.00 1,232,538.89 44.20 22 1,758,150.00 461,769.25 665,165.00 1,126,934.25 64.10 23 2,500,000.00 601,650.00 1,828,000.00 2,429,650.00 97.19 Total 27,469,739.20 6,414,293.47 10,917,875.32 17,332,168.79 63.19 Cycle 2 No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX 24 992,750.00 37,272.69 43,452 80,724.69 8.13 25 187,910.00 3,000.00 1.60 26 1,121,950.00 35,374.15 3.15 27 865,070.00 4,000.00 0.46

41 Spent / Commitment (RM)
No Allocation (RM) Spent / Commitment (RM) TOTAL SPE,NT (RM) % Expenditure OPEX CAPEX 28 824,068.00 0.00 29 697,300.00 133,955.09 9,898.16 143,853.25 20.63 30 268,850.00 5,000.00 1.86 31 296,400.00 32 995,790.00 54,000.00 5.42 33 921,500.00 33,736.22 3.66 34 1,253,050.00 11,645.16 0.93 35 851,200.00 94,197.19 11.07 36 835,050.00 75,259.00 9.01 37 1,061,150.00 39,700.00 3.74 38 1,675,895.00 39,570.10 2.36 39 727,463.00 4,584.00 0.63 40 1,302,070.00 38,475.88 19,672.00 58,147.88 4.47 41 950,000.00 60,176.00 6.33 42 769,690.00 48,727.28 43 257,450.00 16,063.70 6.24 44 1,799,718.00 79,557.70 87,000.00 166,557.70 9.25

42 Spent / Commitment (RM)
No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX 45 374,110.00 5,000.00 28,715.00 33,715.00 9.01 46 348,460.00 0.00 47 1,126,795.00 74,244.74 6.59 48 1,892,448.00 5,333.00 16,488.00 21,821.00 1.15 49 2,290,000.00 50 547,580.00 10,274.27 7,800.00 18,074.27 3.30 Total 25,233,717.00 909,146.17 213,025.16 1,122,171.33 4.45

43 HUMAN CAPITAL DEVELOPMENT (as at 15 august 2012)
No Category Local International TOTAL 1. RA 23 19 42 2. RA + Student i. Master Student 43 85 ii. PhD Student 28 71 99 3. Student 13 8 21 20 14 34 4. HIR-Post Doc * 1 3 4 5. Senior Researcher ** 128 160 288 * = fresh PhD holder ** = PhD with 5 years experiences

44 KPI ACHIEVEMENT (as at 15th august 2012)
Cycle 1 Tier 1 (T1) Bright Spark (BS) Academic Icon (AI) Patent (P) Total KPI Y1 Y2 Y3 Y4 Y5 T1 BS AI P Proposed 24 94 130 144 182 4 28 35 33 37 3 8 9 10 1 16 26 38 58 574 137 139 Actual 78 15  6 15  6 % 66.1 46.9 27.3 35.3 13.6 10.9 7.9 4.3

45 Cycle 2 Tier 1 (T1) Bright Spark (BS) Academic Icon (AI) Patent (P)
Tier 1 (T1) Bright Spark (BS) Academic Icon (AI) Patent (P) Total KPI Y1 Y2 Y3 Y4 T1 BS AI P Proposed 87 146 176 189 17 21 14 4 5 10 8 7 20 32 598 69 27 64 Actual 9 1  5 % 10.3 29.4 25 1.5 7.2 3.7

46 IMPACT TO SOCIETY Prof. Dr. Ir. Mohd. Zamin Bin Jumaat
There will be a new solution for concrete production using local waste materials which comply with green technology today. It would be more economical to use this type of concrete as an alternative to the current product 2. Prof. Ir. Dr. Fatimah Ibrahim The project will lead to the production of affordable, faster , portable and accurate Dengue fever detection and control equipment. Thus, the Health Department will have more time to control and cure the fever among the affected patients. 3. Dr. Chong Wen Tong This project very beneficial to the society because it will increase the income per capita of the farmers and reduce environmental impact

47 IMPACT TO SOCIETY 4. Prof. Dr. Masjuki Haji Hassan
This project will contribute to clean diesel technology development and promote more biodiesel for automotive application in future. Thus, the after-treatment technologies developed in this project can reduce hazardous emission and improve public health security. 5. Madam Norrima Mokhtar Enabling the disable community to have better and more independent life 6. Prof. Ir. Dr. Mohd. Ali bin Hashim The fuel cell system developed can be used as a direct source of power as it is renewable as well as environmentally friendly. Thereby reducing the pollution level in urban areas of the country

48 IMPACT TO SOCIETY 7. Assoc. Prof. Dr. Norhayati Soin The accurate prediction modeling and guardbanding from this project can enhance the lifetime of electronic products. 8. Dr. Hendrik Simon Cornelis Metselaar This project very beneficial to the society and environment because its will solve large scale energy storage problem for transportation, commercial and domestic sectors and reduce environmental negative impact. 9. Prof. Dr. Hew Wooi Ping Provide renewable energy based free electricity to the people in the remote villages. With access to electricity, these people can have clean and purified drinking water and have more economic activities thus uplifting their living standards.

49 THANK YOU

50 HIGH IMPACT RESEARCH (HIR) CYCLE 1 – 12TH MONTH PROGRESS REPORT
UNIVERSITI MALAYA [ ] FACULTY OF SCIENCE CYCLE 1 – 12TH MONTH PROGRESS REPORT 11th September 2012 Ministry of Higher Education

51 FACULTY FLAGSHIP PROJECTS (as at 15th August 2012)
Cycle 1 No. Projects PI Overall Achievement Project 1. Femtosecond laser and terahertz generation for photonics applications Prof. Dr Harith Ahmad 76-100% OS 2. Functional Molecules for Life-Style Diseases Prof Dr. Sri Nurestri Abd Malek 3. Metal-organic frameworks for luminescence and nanoparticle generation Prof Dr. Edward R.T. Tiekink 4. Molecular devices for nanoscale applications Professor Dr. Yatimah Binti Alias 5. Bioorganic and Medicinal Chemistry and Organic Synthesis Professor Dr Kam Toh Seok 6. Synthesis and Application of Low Dimensional Materials Professor Datin Dr. Saadah Abdul Rahman 50-75% 7. An Empirical Kinetic Approach to Study the Occurence of Ion Exchange at the Aqueous Cationic Micellar Surface Professor Dr Mohammad Niyaz Khan 8. Mechanism of antimicrobial peptides on targeted bacterial membrane Assoc Prof Dr Koshy Philip 9. Bioactive compounds from Malaysian Plants Professor Datuk Dr A.Hamid A.Hadi 10. Understanding Guerbert glycosides' self-assembly structures & dynamics for functional nano-biology Professor Dr. Rauzah Hashim 11. Nanocavities for fuel storage Professor Dr. Edward R.T. Tiekink 12. Network Analysis of Social, Technological and Biological Networks Professor Dr. Kurunathan Ratnavelu 26-50% * AS = ahead of schedule OS = on schedule BS = behind schedule

52 BUDGET expenditures (as at 15th August 2012)
Cycle 1 No Allocation (RM) Spent / Committed (RM) Total Spent (RM) % Expenditure OPEX CAPEX 1. 1,460,600.00 82,265.74 429,000.00 511,265.74 35.0 2. 7,010,395.60 2,708,476.97 2,493,705.30 5,202,182.27 74.2 3. 2,031,300.00 1,385,220.24 567,374.00 1,952,594.24 96.1 4. 1,642,152.00 795,367.88 364,079.96 1,159,447.84 70.6 5. 2,873,980.00 701,489.09 2,064,163.00 2,765,652.09 96.2 6. 6,124,552.75 131,245.74 5,791,327.16 5,922,572.90 96.7 7. 522,300.00 100,658.90 153,407.00 254,065.90 48.6 8. 852,210.00 261,259.00 250,650.00 511,909.00 60.1 9. 8,836,300.00 1,461,673.24 4,279,173.00 5,740,846.24 65.0 10. 891,300.00 144,556.30 256,399.00 400,955.30 51.0 11. 602,980.00 383,128.14 135,841.18 518,969.32 86.1 12. 1,161,141.45 8,265.94 199,800.00 208,065.94 17.9 TOTAL ,009,211.80 8,163,607.18 16,984,919.60 25,148,526.78 73.9%

53 HUMAN CAPITAL DEVELOPMENT
No Category Local International TOTAL 1. RA 29 4 33 2. RA + Student i. Master Student 41 6 47 ii. PhD Student 27 17 44 3. Student 18 2 20 24 4. HIR-Post Doc * 1 5. Senior Researcher ** 136 35 171 * = fresh PhD holder ** = PhD with 5 years experiences

54 KPI ACHIEVEMENT Tier 1 (T1) Bright Spark (BS) Academic Icon (AI) Patent (P) Total KPI Y1 Y2 Y3 Y4 Y5 T1 BS AI P Proposed 52 131 144 155 153 23 46 44 3 2 4 5 14 21 27 37 635 203 17 99 Actual 68* 39 - 11 7* 107  16  10 Percentage % 130.8 29.8 21.7 23.9 100.0 21.4 16.9 7.88 17.6 10.1 * Excellent performance in Tier 1 publications and Patent for Year 1

55 PANEL EVALUATION REPORT
Held on 15 August 2012 Progress achievement evaluation based on : 12th Months Progress Report for Cycle 1 – 12 projects (July 2011 – August 2012) Panel members - HIR Committee, Faculty of Science :- Professor Dato’ Dr. Mohd. Sofian B. Azirun Prof. Dr. Sithi V. Muniandy Prof. Dr. Chong Ving Ching

56 PANEL EVALUATION REPORT
No Project Achievement General Comments Recommendation 1 Good Usage of Vote (Salary & Wages) and Vote (Research Material) is rather low. The researchers are advised to expedite the purchasing of necessary materials and also in hiring RA/GRAs. Continuation 2 Spending of Vote (Maintenance & Repairs), Vote (Travelling) and Vote (Rental) are quite low. The researchers have been asked to take necessary steps to utilize the fund. The KPI of Bright Spark has not been achieved. The PI & co-researchers have been asked to nominate suitable postgraduate candidate for Bright Spark program. 3 Acceptable As for publication KPI, number of Tier 1 journal publications still below target. However, some of works have been published in reputable high impact journal. 4 Good overall performance with notable publication output. 5 6 The PI and co-researchers are requested to show evidences of acknowledgement to HIR grant in recent (2012) publications. 7 The PI and co-researchers need to monitor project progress and strategize ways to ensure milestones and project KPIs are achieved. 8 Target output of Tier 1 publication has not been achieved. Most of the manuscripts are still in submission stage. 9 10 Fung utilization need to be expedited. Overall project achievement is satisfactory. 11 Number of Tier 1 Publications doesn’t meet the proposed target. However, there are publications in high impact journals, 12 The PI and researchers must re-evaluate the project activities and project team strength in order to make reasonable progress in research output (Tier 1 journal publications and human resource development) Request for another report in 4 months

57 IMPACT TO SOCIETY Project 1 Project 2 Project 3
Femtosecond Laser and Terahertz Generation for Photonic Applications (PI: Prof. Dr. Harith bin Ahmad) Functional Molecules for Lifestyle Diseases (PI: Datin Prof. Sri Nurestri Abd Malek) Metal-organic Frameworks for Luminescence and Nanoparticle Generation (PI: Prof. Dr Edward R.T. Tiekink) The outcomes of this project has significance to the society especially in internal security such as detecting explosive, medical applications and also scientific research. Research on functional molecules from plants and mushroom will lead to significant contribution in the search of prevention agents to reduce the occurence of cancer, diabetes, cardiovascular diseases and neurological disorders in humans. The scientific data from our studies can help in the acceptance of complementary medicine by doctors trained in current approaches to treat diseases. Contribute to an understanding of supramolecular aggregation patterns and the design of advanced materials that will have applications as gas reservoirs, molecular magnets and energy storage materials.

58 IMPACT TO SOCIETY Project 4 Project 5 Project 6
Molecular Devices for Nanoscales Application (PI: Prof. Dr. Yatimah Alias) Bioorganic and Medicinal Chemistry and Organic Synthesis (PI: Prof. T S Kam) Synthesis and Application of Low Dimensional Materials (PI: Prof. Datin Dr. Saadah Abdul Rahman) This invention will address the novel nanosensors based on non-enzymatic analysis, giving new nanosensors for bio-medical and health applications. Continuing documentation of chemical constituents (secondary metabolites) in Malaysian plants and microorganisms. Potential applications of bioactive compounds as models or templates for drug development studies –may in principle lead to new pharmaceuticals. The synthesis of low-dimensional nanostructures in this research will lead to innovative development of high-performance and energy-efficient optoelectronic devices applicable in lighting, data-storage and ICT products, promoting greener and sustainable living to the society.

59 IMPACT TO SOCIETY Project 7 Project 8 Project 9
An Empirical Kinetic Approach to Study the Occurence of Ion Exchange at the Aqueous Cationic Micellar Surface (PI: Prof. Dr. Mohammad Niyaz Khan) Mechanism of Binding of Antimicrobial Peptides on Targeted Bacterial Membranes (PI: Assoc Prof. Koshy Philip) Bioactive Compounds from Malaysian Plants (PI: Prof. Datuk Dr. A. Hamid A. Hadi) The effects of moderately hydrophobic counterions (X) on cationic micellar growth have been studied extensively because of its various industrial applications. We have developed a chemical method to quantify X affinity to ionic micelles and X-induced and temperature induced micellar growth (spherical-to-wormlike micelles-to-vesicles) is now possible. Such a correlation has a predictive power to predict X-induced and temperature-induced micellar growth This project investigates the characteristics of bioprospected antimicrobial peptides and their mechanism of inibiting target microorganisms of importance to public health. This research can lead to significant contribution in upscaling novel antimicrobials for containing the spread of many microorganisms in the community that are gaining resistance to the conventional antibiotics used today. This research will lead to the discovery of bioactive compounds that can contribute to the development of natural drugs which are now in more demand as compared to synthesized drugs.

60 IMPACT TO SOCIETY Project 11 Project 12 Project 13
Understanding Guerbet Glycosides Self-assembly Structures and Dynamics for Functional Nano-biotechnology (PI: Prof. Rauzah Hashim) Nanocavities for Fuel Storage (PI: Prof. Dr Edward R.T. Tiekink) Network Analysis of Social, Technological and Biological Networks (P.I: Prof. Dr. Kurunathan Ratnavelu) Guerbet gylcosides have been the potential for the formulation of new drug delivery system. This project has sucessfully demonstrated this applications. Other potential application such as membrane protein crystalization has also been explored. The work from these research has been published in high impact journals and has initiated many collaborations world-wide. To generate molecules gold-rich clusters designed to optimise luminescent behaviour for applications in energy storage, sensing and biology. To design novel organic, including co-crystals, and metal-based compounds as potential therapeutic agents against various ailments including cancer, inflammatory disease, tropical diseases, viruses and fungi. There is a unique academic and commercial opportunity to develop network research in Malaysia, as vast stores of computerised data and methods can be tapped to address various local and global research problems.

61 THANK YOU

62 HIGH IMPACT RESEARCH (HIR) UNIVERSITI MALAYA [2011-2015]
FACULTY OF DENTISTRY CYCLE 1 – 12TH MONTH PROGRESS REPORT CYCLE 2 – 6TH MONTH PROGRESS REPORT 11th September 2012 Ministry of Higher Education

63 Principal Investigator (PI)
HIR-MoHE GRANT(CYCLE 1) No. Research Title Principal Investigator (PI) & Co- PI Overall achievement Status 1 Dental derived stem cells for regenerative therapies Prof. Dr. Noor Hayaty Abu Kasim 76-100% OS 2 Pre-clinical assessment of autologous/allogeneic mesenchymal stem cells derived from various sources Assoc. Prof. Dr. Sabri Musa; Co-PI:Prof. Dr. Noor Hayaty Abu Kasim 3 Constructing the cancer progression model: The identification of key players in malignant transformation Prof. Dr. Zainal Ariff Abdul Rahman ; Co-PI:Prof. Dr. Cheong Sok Ching 4 Periodontal disease: the development of genetic biomarkers and the impact of disease on quality of life Dr. V.Rathna Devi a/p A.Vaithilingam 5 Tissue engineering of oral mucosa Assoc. Prof. Dr. Chai Wen Lin; Co-PI: Prof. Dr. Ngeow Wei Cheong 51-75% 6 Biobanking of oral cancers:An assessment of survival,clinicopathological parameters, management strategies nutrition and genetic susceptibility of patients Prof. Dr. Rosnah Mohd. Zain; Co-PI: Prof. Dr. Zainal Ariff Abdul Rahman 7 The oral health status, unmet needs, barriers and management strategies for dental healthcare among HIV/AIDS and other patients with special needs in Malaysia Dr Jacob John Chiremel Chandy 8 Identification of cancer specific genomic duplications and deletions by use of array based comparative genomic hybridization (aCGH), validation of differentially expressed genes and single nucleotide polymorphisms (SNPs) studies and protein array analysis: possible prognostic tools Co-PI: Dr. Siti Mazlipah Ismail * AS = ahead of schedule OS = on schedule BS = behind schedule

64 Principal Investigator (PI)& Co- PI
HIR-MoHE GRANT(CYCLE 2) No. Research Title Principal Investigator (PI)& Co- PI Overall achievement Project 9 Discovery of single nucleotide polymorphisms (SNPs) for oral cancer prognostication using genome-wide association study (GWAS) and the development of protein biomarker diagnostic test for early detection of oral cancer Assoc. Prof. Dr. Chen Yeng 26-50% BS 10 Nutrigenomics and phospholipid signalling in oral cancer: Nutrient-gene interactions Prof. Ian Paterson, Co PI:Dr. Yap Lee Fah 51-75% OS 11 Optical assessment of enamel and dentinal demineralisation Dr. Chew Hooi Pin 0-25% 12 Quality of life assessment in dental practice: assessing change in quality of life using the oral health impact profile by establishing the Minimal Importance Difference (MID) Assoc. Prof. Dr. Roslan Saub 13 Study of the craniofacial form of the normal and with anomalies of malaysian population using 3-dimensional imaging Assoc. Prof. Dr. Siti Adibah Othman 14 Optimization of fabrication techniques for novel functionally graded dental post and its in-vitro and in-vivo evaluation Assoc. Prof. Dr. Hadijah Abdullah, Co PI: Prof. Dr. Noor Hayaty Abu Kasim 15 In vitro microbiological and tissue culture studies for oral healthcare products Assoc. Prof. Dr. Fathilah Abdul Razak * AS = ahead of schedule OS = on schedule BS = behind schedule

65 Principal Investigator (PI)& Co- PI
HIR-MoHE GRANT(CYCLE 2) No. Research Title Principal Investigator (PI)& Co- PI Overall achievement Project 16 Microscopy and physiological studies on the effect of the oral healthcare products on the oral ecosystem Assoc. Prof. Dr. Marina Mohd. Bakri 0-25% BS 17 Effect of plant extracts on the expression of genes responsible for the colonisation of dental plaque microorganisms Dr Wan Himratul Aznita Binti Wan Harun 26-50% 18 Assessing the oral health needs of Malaysian indigenous population and development of a new dental health education strategy Dr. Nor Himazian Mohamed, Co PI: Dr. Kamran Habib Awan 19 Anatomical structural variations in the maxillofacial region Prof. Dr. Phrabhakaran Nambiar 20 Identification and characterization of Host Immonogenic Proteins in the sera of Schizophrenic patients and its correlation with T. gondii infection Assoc. Prof. Dr. Chen Yeng 51-75% OS 21 Novel tissue expander to facilitate maxillary expansion in treating crossbite and transverse maxillary hypoplasia Assoc. Prof. Dr. Zamri Radzi, Co. PI: Prof. Dr. Noor Hayaty Abu Kasim * AS = ahead of schedule OS = on schedule BS = behind schedule

66 CYCLE 1: 2012 BUDGET EXPENDITURES Spent / Commitment (RM)
No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX 1 1,476,000.00 951,202.50 300,000.00 1,251,202.50 84.77 2 869,800.00 291,570.35 362,034.76 653,605.11 75.14 3 1,836,250.00 387,089.16 1,150,000.00 1,537,089.16 83.71 4 97,708.00 84,780.85 - 86.77 5 504,220.00 64,752.00 152,612.00 217,364.00 43.11 6 922,013.00 208,600.63 204,533.00 413,133.63 44.81 7 193,610.00 133,851.37 69.13 8 1,143,968.00 972,514.51 85.01 Total 7,043,569.00 3,094,361.37 2,169,179.76 5,263,541.13 74.73

67 CYCLE 2: 2012 BUDGET EXPENDITURES Spent / Commitment (RM)
No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX 9 265,232.00 120,449.60 45.41 10 270,758.00 143,334.74 52.94 11 878,750.00 48,110.00 4,450.00 52,560.00 5.98 12 94,905.00 - 0.00 13 354,350.00 13,846.34 3.91 14 261,659.00 36,095.94 13.80 15 165,680.00 10,444.21 6.30 16 147,250.00 5,254.31 3.57 17 120,650.00 18,123.61 7,366.00 25,489.61 21.13 18 139,650.00 9,564.20 6.85 19 69,825.00 5,650.00 8.09 20 134,900.00 100,429.89 74.45 21 3,062,325.00 9,241.08 0.30 Total 5,965,934.00 520,543.92 11,816.00 532,359.92 8.92

68 OVERALL: 2012 BUDGET EXPENDITURES Spent / Commitment (RM)
No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX Total 13,009,503.00 3,614,905.29 2,180,995.76 5,795,901.05 44.55

69 CYCLE 1 KPI (2011-2015) HUMAN CAPITAL (2011-2012) Tier 1 (T1)
Tier 1 (T1) Bright Spark (BS) Academic Icon (AI) Patent (P) Total KPI Y1 Y2 Y3 Y4 Y5 T1 BS AI P Proposed 4 17 23 26 31 3 1 5 2 101 8 10 Actual  0 HUMAN CAPITAL ( ) No Category Local International TOTAL 1. RA 13 2 15 2. RA + Student i. Master Student 4 1 5 ii. PhD Student 3. Student 4. HIR-Post Doc * 5. Senior Researcher** 21 3 24 * = fresh PhD holder ** = PhD with 5 years experiences

70 CYCLE 2 KPI (2012-2015) HUMAN CAPITAL (2012) Tier 1 (T1)
Tier 1 (T1) Bright Spark (BS) Academic Icon (AI) Patent (P) Total KPI Y1 Y2 Y3 Y4 T1 BS AI P Proposed 11 24 35 48 1 118 3 Actual HUMAN CAPITAL (2012) No Category Local International TOTAL 1. RA 13 4 17 2. RA + Student i. Master Student 3 ii. PhD Student 1 5 3. Student 2 11 4. HIR-Post Doc * 5. Senior Researcher** 22 6 28 * = fresh PhD holder ** = PhD with 5 years experiences

71 PANEL EVALUATION REPORT
Held on 15 August 2012 Evaluated Projects based: Cycle 1- 12th Month Progress Report (July 2011 to June 2012) Cycle 2- 6th Month Progress Report (Mac 2012 to August 2012) submitted by PIs on August 2012 Panels (HIR committee member) :- Cycle 1 Prof. Dr. Mohd Rais Bin Mustafa (Dean’s of HTM Cluster, UM) Prof. Dr. Ngeow Yun Fong(Faculty of Medicine,UM) Cycle 2 Prof. Dr. Rosnah Mohd. Zain (HIR committee chairperson) Prof. Dr. Lui Joo Loon (Faculty of Dentistry, UM)

72 PANEL EVALUATION REPORT- CYCLE 1
No Project Achievement General Comments Recommendation 1 Acceptable 1 paper published and 3 being written ready for submission Continuation 2 Good On-course satisfactory progress 3 Research at preliminary stage. Progress thus far is satisfactory 4 In the process of sample collection, almost 50% done. Lab work to be followed in 2013 5 Need to identify more research assistants to work on the project 6 Good progress with 1 paper published 7 Awaiting data analysis 8 _

73 PANEL EVALUATION REPORT- CYCLE 2
No Project Achievement General Comments Recommendation 9 Good _ Continuation 10 11 Acceptable Had problems in acquiring equipment, to get PI and RA’s to start process of acquiring equipment this year which will continue into 2013 12 PI need to hire RA as soon as possible 13 14 to expedite the process of appointing post-doc Request for another report in 4 Months 15 16 to work immediately on procurement of research material 17 to work on procurement of research material 18 PI can arrange with the Dental Informatics Unit for loan of the video camera and the laptop Continuation. 19 20 21

74 Project 6: Prof. Dr. Rosnah Mohd. Zain
IMPACT TO SOCIETY Project 6: Prof. Dr. Rosnah Mohd. Zain The research output arising from the maintenance of the MOCDTBS would assist clinicians/ healthcare providers in better management of the patient which could translate to better patient prognosis. Also dissemination of information on oral cancer to the public which is one of the objective in this study would increase the knowledge of the public on this cancer which is less well known as compared to other cancers and empower them to fight against this disease.

75 Thank you For the support

76 HIGH IMPACT RESEARCH (HIR) UNIVERSITI MALAYA [2011-2015]
FACULTY OF COMPUTER SCIENCE & INFORMATION TECHNOLOGY CYCLE 1 – 12TH MONTH PROGRESS REPORT CYCLE 2 – 6TH MONTH PROGRESS REPORT 11th September 2012 Ministry of Higher Education

77 FCSIT PROJECTS (as at 15th August 2012)
Cycle 1 No. Projects PI Overall Achievement Status 1. Unified Scalable Information Hiding Dr. Wong Kok Sheik 76-100% OS 2. Natural Computation Via Molecular Computing : Towards The Design, Development And Implementation of Self-Organized Molecules As Information Processing Substrate Dr. Effirul Ikhwan Ramlan 3. Mobile Cloud Computing : Device and Connectivity Assoc. Prof. Dr. Abdullah Gani 4. Recursive Approach For The Design of Asynchronous Sequential Circuits Dr. Ziaur Rahman 51-75% 5. Multimodal Engagement For Children With Communication Disabilities Prof. Dr. Siti Salwah Salim 6. A Generic/Natural Language Expert System for Robotic and Bazar Simulation Dr. Ng Liang Shing * AS = ahead of schedule OS = on schedule BS = behind schedule

78 FCSIT PROJECTS (as at 15th August 2012)
Cycle 2 No. Projects PI Overall Achievement Project 1. Human-Robotic Interaction (HIR) Algorithm in Robot-Based Intervention Dr. Chan Chee Seng 51-75% OS 2. Efficient Operational Rescue in Vehicular Networks Dr. Rafidah Md Noor 3. Mirror Neuron and Quantum Mechanics Based Neural Architecture for Humanoid Prof. Dr. Loo. Chu Kiong 4. Scientific Mapping and Research Assessment of STEM Scholarly Communication Assoc. Prof. Dr. Abrizah Abdullah 5. Implementation of Secure Framework for Electronic Medical Record (EMRs) Assoc. Prof. Dr. Miss Laiha Mat Kiah 6. An Approach using New Information Extraction Based Traceability and Adaptive Clustering Techniques to Trace and Cluster Requirement for Software Maintenance and Quality Assessment Prof. Dr. Lee Sai Peck * AS = ahead of schedule OS = on schedule BS = behind schedule

79 BUDGET expenditures Cycle 1 Cycle 2 No Allocation Spent / Committed
Total Spent (RM) % Expenditure OPEX CAPEX 1. 126,025.00 52,257.50 40,387.00 92,644.50 (73.5%) 2. 457,635.00 284,492.00 14,072.00 298,564.00 (65.2%) 3. 801,400.00 270,239.89 411,475.00 681,714.89 (85.1%) 4. 1,040,400.00 236,600.00 232,900.00 469,500.00 (45.1%) 5. 342,615.00 213,126.27 104,204.00 317,330.27 (92.6%) 6. 365,658.00 79,174.00 28,840.00 108,014.00 (29.5%) Total 3,133,733.00 1,135,889.66 831,878.0 1,967,767.66 (62.8%) Cycle 2 No Allocation Spent / Committed Total Spent % Expenditure OPEX CAPEX 1. 208,620.00 57,600.00 44,170.00 101,770.00 (48.8%) 2. 161,025.00 78,339.00 32,164.00 110,503.00 (68.6%) 3. 456,000.00 142,000.00 157,059.00 299,059.00 (65.6%) 4. 90,250.00 45,840.00 (50.8%) 5. 142,880.00 90,000.00 (63.0%) 6. 98,800.00 39,584.00 (40.1%) Total 1,157,575.00 453,363.00 233,393.00 686,756.00 (59.3%)

80 HUMAN CAPITAL DEVELOPMENT (Cycle 1)
No Category Local International TOTAL 1. RA 6 3 9 2. RA + Student i. Master Student 1 10 11 ii. PhD Student 2 5 7 3. Student 4. HIR-Post Doc ** 5. Senior Researcher 12 21 33 * = fresh PhD holder ** = PhD with 5 years experiences

81 HUMAN CAPITAL DEVELOPMENT (Cycle 2)
No Category Local International TOTAL 1. RA 1 6 7 2. RA + Student i. Master Student 2 3 ii. PhD Student 3. Student 4 5 4. HIR-Post Doc * 5. Senior Researcher ** 22 26

82 REASONS LACK OF LOCAL STUDENTS
Industry salary attraction Low interest in research Action taken : Roadshows to identify potential student in IPTAs and IPTSs Advertise in multiple medium To offer attraction incentive

83 KPI ACHIEVEMENT (CYCLE 1)
Tier 1 (T1) Bright Spark (BS) Academic Icon (AI) Patent (P) Total KPI Y1 Y2 Y3 Y4 Y5 T1 BS AI P Proposed 4 11 19 20 21 7 6 5 2 3 1 10 13 75 29 32 Actual 15*/15  1 15*/15  * Under Review

84 KPI ACHIEVEMENT (CYCLE 2)
Tier 1 (T1) Bright Spark (BS) Academic Icon (AI) Patent (P) Total KPI Y1 Y2 Y3 Y4 T1 BS AI P Proposed 1 4 12 11 28 2 Actual  0 * Under Review

85 PANEL EVALUATION REPORT
Held on 15 August 2012 Evaluated Projects based on 12th Months for Cycle 1 & 6th Months for Cycle 2 Progress Report (July 2011 to June 2012) and (Mac 2012 – August 2012) Updated progress reports were submitted by PIs by 15 August 2012 Panels :- Professor Dr. Masjuki Haji Hassan Professor Dr. Sulaiman Wadi Harun

86 PANEL EVALUATION REPORT
No General Comments Recommendation 1 Good progress overall and project on track Continuation 2 Need convert effort to start publishing 3 To find collaborators from very established institution and to recruit local Ras for new appointment 4 Make effort to recruit local Ras and to appoint suitable postdoc – must be working in the area of research 5 Good Progress 6 Overall progress is quite slow 7 8 Need local RAs 9 10 Project on track 11

87 IMPACT TO SOCIETY 1. Dr. Wong Kok Sheik
Unauthorized viewing, information leakage, and illegal re-distribution are some of the severe threats for multimedia contents, which triggered privacy issues and caused profit lost in billions of dollars every year. This project aims at unifying both disciplines of data embedding and perceptual encryption into a signal framework to protect and manage multimedia contents. Ultimately, this project generalizes the unified framework to embed data directly into the encrypted content to ensure that privacy is held at the highest level 2. Dr. Effirul Ikhwan Ramlan There remains a number of unanswered questions in science, but ultimately those questions are directed towards improving oneself (i.e., to prolong our life). Prevention is always better than cure, however to prevent is, (in an essence translates) to have the ability to program. This project serves as a platform to enable oneself to be programmed through the creation of new biological products (or machines) which function as "smart" medical therapy systems, drug-delivery and detection mechanisms. Thus introducing a new building block for the next century of computing. 3. Prof. Madya Dr. Abdullah Gani Leverage the potential of smart mobile devices into Rich Internet Application and Big Data transmission over cloud computing architecture.

88 IMPACT TO SOCIETY 4. Dr. Ziaur Rahman
The contribution aimed at developing new knowledge to extend the scientific frontier. The outcome has very good practical applications and can benefit society significantly if proper commercialization is performed. 5. Prof. Dr. Siti Salwah Salim This research is among pioneer projects in Malaysia, and the findings will be of great benefit in developing more independent living skills for Malaysian children with communication disabilities. 6. Dr. Ng Liang Shing This project deals with the following fundamental issues concerning the society (A) How human intelligence arises, how to create artificial intelligence systems which is equal or more superior than human beings (Program modifier) (B) How to make a better Web, better than the Semantic Web (Universal Data Exchange, UDEX) (C) How to combine the above to make Internet a Super Intelligence System (more intelligent than human beings (D) How to use the above to simulate and investigate social problems, especially finance, economy and agriculture 7. Dr. Chan Chee Seng Of all the threats to human society, including war, disease and natural disaster, one outranks all others. It is the ageing of the human population. This research provides a process by which a socially assistive robot is developed and used as part of a therapeutic intervention for elderly with Alzheimer's disease.

89 IMPACT TO SOCIETY 8. Dr. Rafidah Md Noor
The project has an impact especially to the rescue operation committee and generally to the society. The intelligent transport system developed is beneficial to the rescuer in their daily operation. The project investigates the noise pollution (environment) related to the operation of rescue team. 9. Prof. Dr. Loo Chu Kiong The HIR project "Quantum Mechanics and Mirror-neuron Based Imitative Learning" is the cutting-edge attempt to realize quantum computing in robotics. The robot can emulate empathic interaction and induce therapeutic effect for patients with Dementia, mild cognitive impairment and autism. 10. Assoc. Prof. Dr. Miss Laiha Mat Kiah Current scenarios observe that many hospitals, medical centers or even government agencies are resisting to implement and use the electronic medical records (EMRs), mainly due to the privacy and security issues. The aim of this project is to provide security solutions for implemetation of EMR which can be utilized by Malaysian government particularly Health department to achieve secure implementation and management of EMRs in the medical/health systems. While keeping EMRs safeguarded in terms of Confidentiality, Integrity and Availability, people (be it health practitioners, patients, or visitors) are able to use the Health or Hospital Information System facilities securely and confidently, anytime, anywhere.

90 IMPACT TO SOCIETY 11. Prof. Dr. Lee Sai Peck
11. Prof. Dr. Lee Sai Peck The proposed techniques help software developers to effectively identify traces of features in the source code of a large-scale software system with ease for sustainable software evolution and maintenance, thus leading to development time and cost reduction. Feature location is one of the most frequent maintenance activities used to identify an initial relevant location in the source code that implements certain functionality in a software project. For large-scale software, the number of files and methods can be very high and finding the right locations to the change requests can be extremely challenging and time consuming. The proposed techniques that support this activity can help software maintainers and new developers who are not familiar with the software project to effectively support software changes during software evolution with the aim to achieve sustainable high-quality evolution of software. 

91 THANK YOU

92 HIGH IMPACT RESEARCH (HIR) UNIVERSITI MALAYA [2011-2015] CHANCELLORY
CYCLE 1 – 12TH MONTH PROGRESS REPORT CYCLE 2 – 6TH MONTH PROGRESS REPORT 11 September 2012 Ministry of Higher Education

93 Chancellory Flagship projects
Special committee chaired by Tan Sri VC to monitor progress Multidisciplinary research projects in biological, health, engineering, physical, chemical and social sciences Targeting top 10% of Tier 1 ISI/WoS journals All projects well-funded and involve academic icons, including Members of the UM HIR Advisory Council

94 Um HIR advisory council

95 Um HIR advisory council

96 OPENING COURTING ANOTHER NOBEL LAUREATE FOR CHANCELLORY FLAGSHIP PROJECT
Prof. Jules Hoffmann, France 2011 Nobel Prize in Physiology or Medicine French Embassy bringing him to KL in November 2013 Agreed to collaborate on Plasmodium knowlesi project under Cycle 3 MoHE

97 CHANCELLORY FLAGSHIP PROJECTS (as at 15th August 2012)
Cycle 1 No. Projects PI Overall Achievement Status 1. Bacteria Quorum Quenching Dr. Chan Kok Gan 76 – 100 % OS 2. Molecular Genetics Prof. Dr. Jamuna Vadivelu 51 – 75 % 3. Mesenchymal Stem Cell Prof. Dr. Tunku Kamarul Zaman 4. Quantum & Laser Physics Assoc. Prof. Dr. Raymond Ooi 5. Self Assembly Prof. Dr. Rauzah Hashim 6. Breast Cancer Prof. Dr. Yip Cheng Har 7. Flat Fibre Assoc. Prof. Dr. Faisal Rafiq 8. Bioinformatics Dr. Lawrence Choo 9. Central Facilities Emer. Prof. Dr. SK Lam * AS = ahead of schedule OS = on schedule BS = behind schedule

98 CHANCELLORY FLAGSHIP PROJECTS (as at 15th August 2012)
Cycle 2 No. Projects PI Overall Achievement Status 10 Parkinson’s Diseases Emer. Prof. Dr. Yong Hoi Sen 76 – 100 % OS 11 Neurosurgery Prof. Dr. Vickneswaran 51 – 75 % * AS = ahead of schedule OS = on schedule BS = behind schedule

99 Spent / Commitment (RM)
BUDGET expenditures Cycle 1 No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX 1 5,135,600.00 2,035,827.08 2,070,732.00 4,106,559.08 80.0 2 10,968,750.00 2,894,576.43 4,576,981.00 7,471,557.43 68.1 3 6,050,860.00 1,798,353.65 1,840,948.00 3,639,301.65 60.1 4 1,350,100.00 134,886.02 10.0 5 4,936,800.00 1,164,852.98 1,716,768.90 2,881,621.88 58.4 6 9,131,463.00 2,471,996.87 3,262,276.77 5,734,273.64 62.8 7 3,031,910.00 717,726.85 912,440.94 1,630,167.79 53.8 8 2,604,550.00 1,154,358.84 764,249.00 1,918,607.84 73.7 9 25,000,000.00 17,648,811.00 70.6 Total 68,210,033.00 12,372,578.72 32,793,207.61 45,165,786.33 66.2

100 Spent / Commitment (RM) Spent / Commitment (RM)
BUDGET expenditures Cycle 2 No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX 10 395,913.00 37,823.00 37,950.00 75,773.00 19.1 11 2,617,250.00 6,330.00 0.00 0.2 Total 3,013,163.00 44,153.00 82,103.00 2.7 Overall No Allocation (RM) Spent / Commitment (RM) TOTAL SPENT (RM) % Expenditure OPEX CAPEX Total 71,223,196.00 12,416,731.72 32,831,157.61 45,247,889.33 63.5

101 HUMAN CAPITAL DEVELOPMENT
No Category Local International TOTAL 1. RA 44 10 54 2. RA + Student i. Master Student 23 - ii. PhD Student 7 9 16 3. Student 8 6 2 4. HIR-Post Doc * 1 5. Senior Researcher ** 3 5 91 24 115 * = fresh PhD holder ** = PhD with 5 years experiences

102 KPI ACHIEVEMENT Tier 1 (T1) Bright Spark (BS)/ CGPA >3.7
Tier 1 (T1) Bright Spark (BS)/ CGPA >3.7 Academic Icon (AI) Patent (P) Total KPI Y1 Y2 Y3 Y4 Y5 T1 BS AI P Proposed 66 118 150 196 222 13 22 24 110 3 10 4 2 1 7 17 752 23 95 184 35 5 Achieved 74 8 12  4 74   12 % 40 % 22.9 % 92 % 80 % 9.8% 7.3% 52.2% 4.2%

103 PANEL EVALUATION REPORT
Held on 16 August 2012 Evaluated Projects based on 1. 12th Month Progress Report (July 2011 to June 2012) submitted by PIs on June 2012 2. 3th Month Progress Report (March 2012 to June 2012) Panels :- Professor Dr. Mak Joon Wah (IMU) Professor Dr. Ho Chee Cheong (ASM)

104 PANEL EVALUATION REPORT
No Project Achievement General Comments Recommendation 1 Very Good Lab infrastructure is inadequate for smooth running of project. This must be addressed by the Aministration. Continuation 2 Acceptable Lab space inadequate. Planning for the manpower development needs improvement for developing local talents. 3 Planning for manpower development needs improvement in development local talents. 4 Good Need to increase the process of purchasing. Address issue of spending budget allocation within time - frame. Need to purchase proposed equipments soon. 5 Seems to encounter some communication difficulties within research group or UM which may jeopardised smooth running of project. 6 Budget spending on track overall. However, the spending of 1 sub-project is low. Needs to speed up purchasing. 7 Phase 1 development in fabrication of the device appears to be on track. Two patent applications to UMCIC have been filled. 8 Number of post - graduate students need to be increased. Otherwise progress is on target. 9 Progress in acquiring equipments which have been budgeted for is hampered due to admin. processes. Many of the equipments are pending for approval for purchase. 10 Not Applicable Project has just started. Not possible to comment on progress since purchasing & recruitment of staff have not started. Should be reviewed in 6-months time. 11 Project has just started and still in its very early stage of commencement. Needs to be reviewed in 6-months time.

105 KEY TIER 1 ISI/WoS PUBLICATIONS
2 articles have already appeared in Nature 3 others are being reviewed by Nature Genetics 1 article in Lancet 4 articles for submission to Nature and 1 to Science by 2013

106 IMPACT TO SOCIETY 1. Chan Kok Gan
Discovered quorum quenching compound in nutmeg (Malabaricone C) Patent filed and will lead to wealth creation of a local natural product 2. Tunku Kamarul Zaman Translation of this in vivo and in vitro research on stem cell research will lead to significant contribution in upscaling to clinical trials in treating cartilage and tendon associated diseases 3. Raymond Ooi Research findings will lead to futuristic technology that will benefit all facets of lifestyles, including optical, information and communication technologies

107 IMPACT TO SOCIETY 4. Yip Cheng Har
Breast cancer study will lead to better prognosis and treatment outcome of the 3 major ethnic groups. Clinical trials utilizing new agents and techniques will benefit women with breast cancer in Malaysia. 5. Faisal Rafiq Mahamd Adikan First fabrication of capillary flat fibre has the potential for wealth creation for the institution and the nation The building of the optical fibre draw tower, the only one in SEA, will provide state-of-the-art facility to develop novel optical fibres for communication, sensing and other important applications The installation of optical sensors in structures such as bridges offer value added features such as maintenance free and intelligent buildings and thus realizing green buildings and structures.

108 IMPACT TO SOCIETY CARY 60 GCMS Central HIR Facility
Many high-end equipment have been installed in Bangunan HIR and this will lead to enhancing research and building up expertise. This will reduce dependence on outside sources and will reverse the trend where UM will be sort after for collaborative research. These equipment will be made available for booking by researchers from IPTAs and IPTS, reducing outsourcing and saving cost to the country. CARY 60 GCMS

109 THANK YOU

110 Penyaluran peruntukan hir (2011 – 2015)
No Tarikh Perkara Jumlah 1 27 Disember 2011 No baucer B0521 RM 40 juta 2 3 November 2011 No Rujukan KPT.W /4/1 Jld 2(34) RM 20 juta 3 16 Januari 2012 Rujukan KPT.P.(S) 400/33/2/1 Jld 3(63) RM 64 juta TOTAL RM 124 juta Peruntukan yang telah komited (VM Lab for 2013) RM 7 juta Baki Peruntukan yang belum di salurkan oleh KPT RM 459 juta

111 TERIMA KASIH


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