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Gene expression Chapter 15 Genes and Development.

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Presentation on theme: "Gene expression Chapter 15 Genes and Development."— Presentation transcript:

1 Gene expression Chapter 15 Genes and Development

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7 Central dogma 1956 version of Central dogma by Francis Crick

8 Central dogma 1958 version of Central dogma

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12 Genetic code

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15 Transcription

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19 DNA P’ase

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21 RNA polymerase-3D at Online Macromolecular Museum

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23 Transcription

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28 RNA polymerase-3D at Online Macromolecular Museum

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32 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. E1I1E2I2E3I3E4I4 Transcription Introns are removed Exons Introns Mature mRNA 3’ poly-A tail5’ cap 3’ poly-A tail Primary RNA transcript DNA template

33 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. E1I1E 2I 2E3I3E 4I 4 Transcription Introns are removed Intron Exon DNA a. b.c. Exons Introns mRNA Mature mRNA 3׳ poly-A tail 5׳ cap 3׳ poly-A tail Primary RNA transcript DNA template b: Courtesy of Dr. Bert O’Malley, Baylor College of Medicine

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35 Translation

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48 Genetic code

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