5Boyd’s Homeostatic Property Clusters Natural kinds are clusters of properties that co-occur because of a homeostatic (similarity generating) mechanism.Normative Constraint: The correct taxonomy in a domain describes phenomenal kinds that correspond to the mechanisms constituting the causal structure of the world.
6Questions and Theses HPC and Mechanisms: A heavenly match? Can the mechanistic structure of the world serve as an objective foundation for the taxonomy of natural kinds?Can the idea of a “natural kind” survive if they are understood in this way?Main Theses:1. The HPC view regresses.2. Pragmatic factors enter ineliminably into our consideration of types of mechanisms.3. The concept of “natural kind” is unnecessary and misleading in sciences such as neuroscience.
7Outline 1. The HPC View and Its Motivations 2. Taxonomic Revision: Lumping and Splitting3. Mechanisms4. Which mechanism?5. Kinds of Mechanisms6. Boundaries of Mechanisms7. Doing Without Natural Kinds
81. The Homeostatic Property Cluster Account of Natural Kinds ConventionalismHPCEssentialismKornblith 1993; Wilson et al. forthcoming
9Essentialists Essentialism Natural kinds are defined by necessary and sufficient conditions.ConventionalismHPCEssentialism
10Common Objections to Essentialism Variability in Biological PopulationsPrototype Structure
11Conventionalism Essentialism Conventionalism HPC There is no objective distinction between natural kinds and any other property cluster.Conventional kinds are “constructed along lines of family resemblance…. What puts things into a family is not nature, but people in concert.Promiscuity! (Boyd 1999)ConventionalismHPCEssentialism
12HPC Objections to Conventionalism Nothing in nature makes it the case that one member of the kind is relevantly similar to other membersPredictionExplanationControlIndy Music?
13HPC in Summary Natural kinds are defined by: B1) Property Cluster: A cluster of properties that regularly occur together.B2) Mechanism: A mechanism that explains why the properties occur together.B3) Causal Import. The cluster figures in important causal generalizations;B4) Maximal accommodation: Any refinement of the definition of the kind either introduces causally and inductively irrelevant distinctions or glosses over causally and inductively relevant similarities.
14B2) Mechanism: A mechanism that explains why the properties occur together. PredictionExplanationControlTo deny B2 yields a simple causal view: causally important and maximally accommodated kinds.But then, what does “natural kind” add over and above “causally relevant variables.”“The essential property that makes particular instances members of the kind is their relation to that causal mechanism [that explains the cluster].
15B3) Causal Import. The cluster figures in important causal generalizations. Pragmatic Reading: Useful.Slides toward conventionalism.Ontic Reading: Makes a difference to something.If deny B3: Simple metaphysical view of kinds: There are kinds wherever there a similarity generating mechanismsBarometers, Storms, and Joint Pain.Too weak for regimenting our taxonomies.
16B4) Accommodation: Weak Reading Members of the kind should be similar enough for our inferential uses of the kind and the instrumental projects that it facilitates (see Boyd 1999)Threatens the normative idea that the mechanistic structure of the world will arbitrate disputes over kindhood.Strong ReadingThe correct description of a kind should be immune to revision in light of further findings about the mechanistic structure of the world.“consists in a certain accommodation between the relevant conceptual and classificatory practices and independently existing causal structures” (Boyd 1997, 55).“The mechanisms that maintain any given HPC are part of the natural world, not simply our way of thinking about or intervening in the world” (Wilson 2005, 118).Should neither (i) gloss over causally relevant differences, nor (ii) recognize causally irrelevant differences.
172. Taxonomic Revision: Lumping and Splitting Strategies for implementing the normative constraint that kinds should track mechanisms.
18The Splitting Strategy Emotion, Schizophrenia, Modularity, Memory From McKusick (1969)
19The Lumping Strategy Freud, Boyer, AIDS From McKusick (1969)
20Splitting, Lumping, and HPC When are two mechanisms of distinct kinds?When are two mechanisms of the same kind?
213. Mechanisms Entities Activities Organization (Bechtel; Craver; Darden; Glennan; Machamer; Wimsatt; and so on)
224. Which Mechanism? Which mechanism guides our taxonomic judgments? *membrane mechanism (b)*electrophysiological causes (a,d)*regulatory mechanisms*proximal antecedent causes*developmental causes*evolutionary causesKeil also includes common effects.Reichenbach’s principle of common cause.Promiscuity!
23Is this a problem? Sometimes they coincide. Often not. Many etiological mechanisms, one constitutive mechanism.HIV infection; clinical depression.One etiological mechanisms, different constitutive mechanismsAIDS; Tertiary syphilisOne and many etiological mechanisms at different stagesNeedles, Sex, Transfusion -> HIV -> AIDSPsychiatric CasesDifferent underlying mechanisms, same treatment groupsStrong Accommodation (B4)demands no further revision on the basis of the causal structure.
24Two possibilities Essentialism Conventionalism HPC Privilege one kind of mechanismNothing in nature earns the privilege.Go pluralist.Weak Accommodation.What counts as “maximally refined” depends on your interests.Cannot settle disputes that arise from attention to different mechanistic entanglements.ConventionalismHPCEssentialism
255. Kinds of MechanismsWhen Are Two Mechanisms Mechanisms of the Same Kind?HPC depends upon a notion of kinds of mechanisms on pains of there being too many natural kinds.Any detectable difference is a causal difference (has import in the weak sense of B3).Why not restrict to only those differences that alter the property cluster? Because that presupposes that we know which properties belong in the cluster.
26Regress Kinds of mechanisms? Kinds of entities, activities, and organizational features?Either way, we only stave off our ignorance of natural kinds a little longer.
27The Scientific Problem HPC kinds tolerate variability.HPC kinds tolerate multiple realization.HPC kinds must be accommodated to the causal structure of the world (B4).If you characterize it too abstractly, you gloss over causally relevant differences.If you characterize it in maximal detail, every mechanism is a kind unto itself.What is the appropriate degree of abstraction?
29A Computational Hippocampus A sequential Hopfield net?A feedback mechanism?A control mechanism
30The PointTwo mechanisms count as the same kind of mechanism according to one schema and as different kinds of mechanisms according to another.We have to balance generalization with the need to recognize causally significant differences.Such balancing is just of the sort of thing that depends on what we are trying to do.Surgery?Modeling?
31A second responseGo promiscuous! Accept all useful characterizations of the mechanism.Glosses over causally relevant differences (contra B4).Reverses the direction of fit; accept the mechanism schema when it is useful.What work is left for mechanisms to do?
32To Summarize Essentialism Conventionalism HPC HPC needs the notion of a kind of mechanism, and so regresses.HPC needs to define an appropriate degree of abstraction in characterizing kinds of mechanisms.Appropriate degree of abstraction depends on what we intend to do with our description.What we intend to do with our description is a fact about how humans find it useful to cluster properties.The correct taxonomy of kinds depends on what we intend to do with it.ConventionalismHPCEssentialism
335. The Boundaries of Mechanisms Which entities, activities, and organizational features are included in the kind of mechanism and which are not?The Ghost of Cartesian MechanismWhat objective feature of the causal structure of the world binds entities, activities, and organizational features into a mechanism?
34Where does one mechanism end and another begins Compartmentalization? (Protein synthesis)Contact Action (Descartes)Moving togetherStable across spatial translation (Ephemeral mechanisms; cf. Glennan).Strength of InteractionBandwidth of Interaction? (Better for cognitive mechanisms than electrophysiology.Relevance Boundaries!
35Another way to make the point… Glennan’s Law: All mechanisms are mechanisms of or for something.How one characterizes the phenomenon determines (in part) what will count as an adequate mechanistic explanation for it.Kauffman’s articulation of parts.Mechanisms are clustered into kinds because of the property clusters they explain.What objectivity is added by the appeal to mechanisms over a cluster view?ConventionalismHPCEssentialism
366. Pragmatics and The Ontic Conception Epistemic Conception: a phenomenon is explained by an argument showing that it was to be expected on the basis of the laws of nature.Ontic Conception (Causal): a phenomenon is explained by its causes and/or mechanisms.Salmon (1989)
37Have I abandoned the ontic conception? NO!1) Mechanistic explanation is still grounded in the causal structure of the world.2) Mechanistic explanations are fundamentally particular; generalization into kinds is tinged by abstraction.3) All explanations are relative to the choice of explanandum phenomenon (which is tinged with our interests) but from there, explanatory relevance is an objective matter.
38Though some ways of sorting mechanisms into kinds are more natural than others, there are no natural kinds of mechanisms (cf. Hacking, Rosey Dawn)We split when splitting makes a difference for our investigative or instrumental objectives.We lump when splitting makes no difference for our investigative or instrumental objectives.It is a fact, objective as any, whether a difference in mechanisms makes a difference for our investigative or instrumental objectives.Objective mechanisms are crucial for our taxonomies, but which taxonomy we find useful is always relative to our practical concerns.
396. Summary/ConclusionLumping and Splitting are common scientific strategies for accommodating kinds to the mechanistic structure of the world.The HPC account regresses.The challenge of saying which mechanism matters for fixing kinds.The challenge of choosing the appropriate level of abstraction for typing mechanisms.The challenge of defining the boundaries of types of mechanisms.This is only a problem if you think that there have to be natural kinds but you want to accommodate the variability and multiple realizability of biological mechanisms.Give up the need for natural kinds in the special sciences.
40Thanks to…Ken Aizawa, Matt Barker, Jim Bogen, Peter Carruthers, Lindley Darden, Carl Gillett, Todd Grantham, Ken Kendler, Max Kistler, Tom Polger, Georges Rey, Eric Seidel, Pamela Speh, Samuli Poyhonen, Dan Weiskopf, Rob Wilson, Petri Ylikoski.