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Mochamad Fahlevi Rizal Endang W Bachtiar Boy M Bachtiar Heriandi Sutadi.

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Presentation on theme: "Mochamad Fahlevi Rizal Endang W Bachtiar Boy M Bachtiar Heriandi Sutadi."— Presentation transcript:

1 Mochamad Fahlevi Rizal Endang W Bachtiar Boy M Bachtiar Heriandi Sutadi

2  Caries Prevalence in Indonesia  Baby bottle tooth decay  Caries Detection for Children  Mucin MG2 responsible to Streptococcus mutans adhesion

3  Salivary mucin MG2  α -enolase Streptococcus mutans

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6  Single monomeric protein  Molecular weigth are less then mucin MG1  Sintesized in acinar serous cell and detected in all sero mucous salivary glands  Adhere with much oral bacteria such as Streptococcus mutans

7  Consecutive Sampling  Inclusion criteria: children between 3 – 5 yo who have dringking milk by bottle history  Unstimulate saliva collecting  ELISA method with anti mucin MG2 antibody in 450 nm

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10 Jumlah Kerusakan GigiJumlah Sampel Rata-rata Nilai OD Mucin Analisis AnovaSum of SquaresFSig. Bebas Karies Between Groups Karies 1- 5 Gigi Within Groups0.297 Karies > 5 gigi Total Total0.342

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12  Caries prevalence was represented by deft  Incresing mucin MG2 concentration will increase caries insidence

13  Mucin MG2 will used to: - caries prediction - caries prevention

14 Mucin MG2 correlate to caries prevance in baby bottle tooth decay and could be a caries predictor and a tool to prevent caries molecularly

15 Part of this research was supported by Risbin Iptekdok Grant Research 2007 from Department of Health Republic of Indonesia

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