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DNA POLIMERASE By: Muhartri Sanjaya20512046 Nishia W Meray20511034.

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Presentation on theme: "DNA POLIMERASE By: Muhartri Sanjaya20512046 Nishia W Meray20511034."— Presentation transcript:

1 DNA POLIMERASE By: Muhartri Sanjaya Nishia W Meray

2 DNA POLIMERASE Replikasi DNA Reparasi DNA reaksi polimerisasi deoksiribonukleotida Rantai DNA

3 Tatanama DNA Transferase EC Kelas Transferase Gugus fosfat

4 Klasifikasi E. Coli Pol I (Kelas A)E. Coli Pol II (Kelas B)E. Coli Pol III (Kelas C) Euryarchaeotic Pol II (Kelas D) Pol β Manusia (Kelas X) E. Coli UmuC/DinB (Kelas Y)

5 Peran DNA Polimerase Elongasi Proofreading

6 Struktur DNA Polimerase Finger Tumb Palm

7 Mekanisme Kerja

8 Residu Katalitik & Efektor Residu Katalitik aspartat 705 dan 882 Efektor yang mengandung ion logam

9 Aplikasi dan Modifikasi DNA Pol I PCR E. Coli Bukan Termofilik Thermus Aquaticus

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