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Bio-organic molecules 1. carbohydrates 2. proteins 3. lipids 4. nucleic acids
Protein function based on gene analysis Dr. Mani Subramanian; Celera Genomics NYTimes 2_14_01
Somatic cells are diploid
Chromosome 4 http://www.ncbi.nlm.nih.gov/cgi-bin/SCIENCE96/chr?4 Huntington’s Disease autosomal dominant Ellis van Creveld Syndrome autosomal recessive
Protein binding 1. specificity 2. affinity 3. saturation 4. competition
A + B C + D
+ 7 kcal/mol + H +
Energy is stored in chemical bonds
Enzyme substrate interactions 1. specificity 2. affinity 3. saturation 4. competition
M.R. Redinbo et al. (1998) Science 279: 1504 Enzyme: Topoisomerase I
Reaction rates What happens when you increase the amount of enzyme? What happens when you increase the amount of substrate?
Atom The smallest units of matter; combines with other atoms to form molecules. Both living and nonliving things are made from atoms.
What our bodies are made of Chemistry of Cells. Nature of Matter All matter is made of atoms. Atoms consist of electrons, protons and neutrons. Molecules.
Chemicals for Life. Carbohydrates Sugars and starch C,H,O Energy source.
Which of the following macromolecules is this? A. lipid B. Carbohydrate C. Protein D. Nucleic acid.
Enzymes. Introduction Enzymes = organic molecules act as catalysts – Type of protein Catalyst = reduce amount of activation energy needed for reaction.
Enzymes Protein Responsible for most cell functions Functions – to build or break apart – Translate DNA – Breakdown food – Put together macromolecules.
Ch. 2: “Chemistry of Life” Vocabulary Review. Matching 1. ion c. atom or molecule that has lost or gained one or more electrons 2. atom a. smallest unit.
4.2 Carbon compounds and cells Life as we know it is carbon based. A carbon atom can form chemical bonds with other carbon atoms in long chains or rings.
1. Can you name this structure? Monosaccharide Organic Compound: Carbohydrate Monomer: Monosaccharide/Glucose.
Chapter 2-1. These molecules have specific jobs in the cell. Carbohydrates Lipids Proteins Nucleic Acids.
Chemical Compound Review. Hydrogen is an example of a. compound. b. organic compound. c. molecule d. element.
Enzymes. What is an Enzyme? Enzymes are types of Proteins! They end in “ase” They speed up chemical reactions… – Also Known As CATALYST.
What do you know? True or False Thumbs up for TRUE Thumbs down for FALSE Monomers are complex large molecules. FALSE.
Life Science Chapter 2-Lesson 3 The Chemistry of Life.
Intro to Bio & Bio-molecule Review JEOPARDY #1 S2C06 Jeopardy Review.
Macromolecules Large molecules in living cells are known as macromolecules --- “giant molecules” Macromolecules are made by joining smaller unites called.
Last Class Protein Protein Carbohydrate Carbohydrate Lipid Lipid Nucleic acid Nucleic acid.
Organic vs. Inorganic Molecules If you understand these building blocks, future units will be a breeze!
Organisms and the Environment Chapter Four: Physical Science Connections 4.1 Elements and Compounds 4.2 The Compounds of Life 4.3 Physical Variables.
LN# 6 Life Substances. How are cells organized? Cells are specialized to do specific jobs. Cells do not work alone. Many thousands of cells make up a.
Cells Chemistry of Life Chapter 2 Objectives: Know the functions of each group of organic compound/macromolecule.
How Cells Function. Video: CCBB-00CF-43A C98A1A92B&blnFromSearch=1&productcode=DETB#
Bio-molecule Review JEOPARDY #1 S2C06 Jeopardy Review.
20,000 GENES IN HUMAN GENOME; WHAT WOULD HAPPEN IF ALL THESE GENES WERE EXPRESSED IN EVERY CELL IN YOUR BODY? WHAT WOULD HAPPEN IF THEY WERE EXPRESSED.
Cellular Metabolism Chapter 4. Introduction Metabolism is many chemical reactionss Metabolism breaks down nutrients and releases energy= catabolism Metabolism.
KEY CONCEPT Carbon-based molecules are the foundation of life.
Macromolecules (Carbohydrates, Proteins, Lipids, Nucleic Acids) By – Nevin Varghese Victor Veras Dapo Adegbile.
Organic Molecules What do you think are the most common elements in the human body? (Hint: look at p. 113 in your pride book to help)
Chapter 2 Chemistry of Life Section 1: Nature of Matter Section 2: Water and Solutions Section 3: Chemistry of Cells Section 4: Energy and Chemical Reactions.
Organic Molecules – large molecules that make up all living organisms.
Chromosomes carry genetic information
The Chemistry of Carbon Organic compounds - compounds created by organisms Organic compounds - compounds created by organisms 4 groups of organic compounds.
Enzymes: They do all the work! Enzymes Proteins Help chemical reactions happen reduce activation energy increase rate of reaction.
ORGANIC CHEMISTRY AND ENZYMES EQ: What kind of organic compound are enzymes and what do enzymes do?
THIS IS Macro- molecules Choo-choo Trains ProteinsChem basics Example Molecules Potpourri.
SB1b - Enzymes SB1c - Macromolecules Test Review
Macromolecules and Enzymes. Enzymes Enzymes – biological catalysts used to speed up reactions The reaction may still occur without an enzyme present,
MACROMOLECULES A very large molecule consisting of many smaller structural units linked together.
Enzymes. Enzymes are Proteins Many of our genes code directly for enzymes Estimated to be about 75,000 different types in the human body.
Cues Elements Within Cell Carbohydrates Lipids Proteins Nucleic Acid Water.
Concept Cards. Section 2.1 Parts of an atom Charge on electrons, location Charge on protons, location Charge on neutrons, location Charge on every element.
MACROMOLECULE REVIEW. Carbon Compounds Most matter in your body that is not water is made of organic compounds Organic compounds contain carbon atoms.
Proteins (enzymes) 3 Major functions: 1 – to provide structure (muscle) 2 – Help control reactions 3 – can speed up reactions (catalysts) ENZYMES = special.
1 10 pt 15 pt 20 pt 25 pt 5 pt 10 pt 15 pt 20 pt 25 pt 5 pt 10 pt 15 pt 20 pt 25 pt 5 pt 10 pt 15 pt 20 pt 25 pt 5 pt 10 pt 15 pt 20 pt 25 pt 5 pt Biomolecules.
DO YOU HAVE THE ENERGY? Chapter 3 REVIEW.
Chemical Reactions chem rxns Everything in living organisms based on chem rxns: Growth, interaction with environment, reproduction, movement…..
Organic Compounds Functional Groups CarbsLipidsProteins
Macromolecules. 1. What does “macro” mean in macromolecules? Macro means large.
Chapter 2. A compound is a substance that is made of two or more joined elements Organic compounds contain carbon atoms(along with other elements)
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