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Neglected issues in obesity epidemic Hugo Rodier, MD Adjunct professor University of Utah College of Health Department of Nutrition School of medicine.

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Presentation on theme: "Neglected issues in obesity epidemic Hugo Rodier, MD Adjunct professor University of Utah College of Health Department of Nutrition School of medicine."— Presentation transcript:

1 Neglected issues in obesity epidemic Hugo Rodier, MD Adjunct professor University of Utah College of Health Department of Nutrition School of medicine (Family and Preventive Dept.)

2 True, but…. Statistics Eat more veggies Exercise Calorie counting Menu listings Food labeling Making committments

3 Shifting emphasis Metabolism TOILing membranes Xenohormesis Nutragenomics Calories AND Information Addiction Food Politics Community structures Pollution Gut connection Thermostat “Birds of a feather” Mind-body-spirit connection Sex (hush…)

4 Metabolism Everything in the Universe is Light Light=Energy and Information, E&I Solar E&I and photosynthesis Top soil Food =Light=E&I Laws of Thermodynamics Thermodynamics in humans= metabolism All cells need E&I to do their job

5 TOILing membranes T oxicity O xidation I nflammation L ess than Optimal Mitochondrial function

6 Xenohormesis Very small molecules (toxins, micronutrients) have a profound effect on cellular function, “What Role Has Nutrition Been Playing in Our Health? The Xenohormesis Connection,” J. Integrative Medicine 2007;6:22 “The dose makes the poison” proven wrong. Ammunition for nutritional, environmental thinkers

7 Nutrigenomics, Nutrigenetics Genetics account for only 5% of the problem Genes are nothing, until copied Food (E&I) influences how our genes are copied Our ancestors’ feeding habits cannot be overcome overnight Indiana Jones discovers ancient tribe deep in the Amazon

8 Calories AND Information Diet soda pop and obesity Why? Artificial sweeteners Bad information in processed foods Counting calories =starving all day Diets high in protein and fiber, regardless of calories, help people lose weight Have you ever seen obese people filling up on fruits and veggies?

9 For nerds “Why obese patients don’t lose weight with low calorie diets?” AJCN 2007;85:346 “Personal metabolomics as a next generation nutritional assessment” J. Nutrition 2003;133:4260 Int J. Obesity Relat Metabolism Diso 2000;24:451. J. Int Med 2003;254:401 Int J. Obes Relat Metab Dis 1996;20:1051 J. Clinical Endocrinology Metabolism 2007;92:386 J. Scientific American Report 2006;16#4:19

10 Addiction Why weight loss programs fail We must have the courage to face the music Behavioral/Public Health approach missing Childhood issues Stress Cell membrane receptors for valium, alcohol, opioids, endorphins and processed sugars

11 Food Politics: “follow the $” Big Food and government Farm bill Corporate farming Codex Food processing= addiction HFCS More $ with processing Disinformation and confusion

12 Community structures Energy economics= E&I; Enron boys Automobile society Urban sprawl Walkable venues= Europe=environmentalism= socialism

13 Pollution Pollution increases TOIL Think of retained exhaust fumes jamming engine Remember diet soda pop Green movement Detoxification to the forefront Antioxidants Persistent Pollutants and the Burden of Diabetes,” J. Lancet 2006;368:558

14 Gut connection Colonization by gut organisms that crave refined sugars, chocolate How did they get there? How does it feel to be controlled by microscopic organisms? “The Planet of Bacteria” The Microgenome: study of genes we carry, most of which belong to intestinal organisms Probiotics help with metabolism J. Diabetes 2007;:56:1761 Aberrant microflora = TOIL J. Cancer Research 2009;69:4827 “ Obesity and Gut Flora,” J. Nature 2006;444:1009

15 Thermostat It’s broken, or TOILing Worse with intestinal inflammation V.A.T. = beer-belly. It sends toxic endocrine signals to thermostat 95% of neurotransmitters in gut Recall feeding healthy baby Another reason we can’t control sugar-cravings

16 “Birds of a Feather” Who we hang out with has powerful influences on our behavior New York Times magazine, Sep 13 th 2009 Peers > parents Obese friends Smoking friends Loneliness= pain J. Science 2003;302:237

17 Mind-Body-Spirit TOIL, the “L” also stands for LOVE, LIGHT (vitamin D3) We create our own reality Rosetto, Pennsylvania Gaia, Atlas: never give up Face your demons “The Most Powerful Therapeutic Force” JAMA 2002;287:1909

18 Sex: best motivation? Health, great motivator… …But, reptile brain cannot be denied, only controlled Use natural forces to our advantage Erectile dysfunction and less vaginal sensation with insulin resistance and poor circulation Who do you want to attract?

19 Solutions: Addressing neglected issues Metabolism TOILing membranes Xenohormesis Nutragenomics Calories AND Information Addiction Food Politics Community structures Pollution Gut connection Thermostat “Birds of a feather” Mind-body-spirit connection Sex (hush…)

20 NSP: supplementation

21 Conclusion Gandhi's advise “It is only with the heart that we can see clearly”


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