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Wani Shaqul Qamar, Talib Khan Sher I Kashmir Institute of Medical Sciences (SKIMS) Nasopharyngeal Carcinoma An 11 Year Study With Respect To Patient Characteristics,

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Presentation on theme: "Wani Shaqul Qamar, Talib Khan Sher I Kashmir Institute of Medical Sciences (SKIMS) Nasopharyngeal Carcinoma An 11 Year Study With Respect To Patient Characteristics,"— Presentation transcript:

1 Wani Shaqul Qamar, Talib Khan Sher I Kashmir Institute of Medical Sciences (SKIMS) Nasopharyngeal Carcinoma An 11 Year Study With Respect To Patient Characteristics, Clinical Aspects & Staging at Presentation

2 R are malignancy C onfusing P oorly understood disease R acial & Geographical Orphanet J Rare Dis 2006;1:23. ICMR Bulletin 2003;33[9]. Cancer Epidemiol Biomarkers PrevCancer Epidemiol Biomarkers Prev 2006;15: Ann Acad Med SingaporeAnn Acad Med Singapore 1990;19:201-7.

3 Anatomy Origin

4 U ncommon in the India Chin J Cancer 2011;30: I ncidence < 1 per 100,000/Yr ICMR Bulletin 2003;33(9)

5 Kashmir Valley - Northern part India Distinct Geography, Climate, Dietary Habits, Lifestyle Socio-culture Aspects

6 Aims & Objectives

7 Demographic Profile Lifestyle Aspects Clinical Presentation Histopathology Stage at Presentation

8 Material & Methods

9 The IEC approval Tertiary referral and University teaching hospital January December 2011 The case sheets – reviewed Demographic Profile, Lifestyle Aspects, Clinical Presentation,Histopathology, Stage at Presentation The standard statistical - Used

10 Observations

11 Age Years Minimum12 Maximum85 Median49 Mean ± SD46.04 ± 16.43

12

13 Demographics

14 Diet & Life Style

15

16 Histopathology

17 Stage at Presentation

18 NPC Cases - Yearly

19 Case 1

20 20 Yr/F Ptosis R>L Loss of vision MRI brain Dec 2010 Normal

21

22 Started on steroids

23 MRI Brain May 2011 Normal

24 MRI Brain October 2011 Enhancement of L Optic Nerve & cavernous sinus

25

26 MRI Nov 2011 BL cavernous sinus & orbital apex syndrome with L optic neuritis

27 “Dilemma Continues”

28 Case 2

29 10 Yr/ male Submandibular swelling months Pain and fever Treated as Mumps and Symptomatically

30 FNACmetastatic deposits undiff CA CECT H&N 4x5.2cm well defined modrately enhancing in NP (R side) ext nasal cavity, infra temp fossa, maxll sinus via orbital fissure into orbital apex, bone destruction, multiple cervical LN NP Bx/ IHC NPC / cytokeratin+

31 Conclusion

32 “Dietary and life Style plays a major role in the etiopatogenesis of NPC in Kashmir”

33 The GPs and Specialty physicians should R/O the possibility of NPC when patient with any of the symptoms of NPC are present

34 Thank you Pray for Kashmir


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