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Nucleic Acids Polymer Individual unit called a (mono)nucleotide DNA is a type of nucleic acid – deoxyribonucleic acid
Nucleotide Structure 3 components: – Pentose sugar (ribose in DNA) – Phosphoric acid – Organic base (always contains nitrogen) Phosphate sugar base Stay the same Changes Contains nitrogen & carbon Pentose sugar (5 Carbon atoms)
4 Bases Purines – –Double ringed structure Pyrimidines – –Single ringed structure
Bondings The base and sugar join with a: glycosidic bond The phosphate and sugar join with an: ester bond Both require a condensation reaction to occur
H H OH Phosphate Sugar Base 2 condensation reactions occur in the formation of a nucleotide: Ester bond Glycosidic bond
Tell me… 4 names of bases in DNA 3 components of a nucleotide 1 place where a condensation reaction occurs 2 types of bonds in a nucleotide 1 difference between purine and pyrimidine bases
Phosphodiester Bonds: the sugar-phosphate-backbone
Complementary Base Pairing *Purines always pair with pyrimidines* A joins to T (2 hydrogen bonds) C joins to G (3 hydrogen bonds) see
C A G T 2 hydrogen bonds 3 hydrogen bonds nm 2nm
Type of BasePurinePyrimidine Structure Bonding relationships Adenine Guanine Thymine Cytosine = hydrogen bond
TypePurinePyrimidine Structure NameAdenine Guanine Thymine Cytosine / Uracil
For the DNA strand 5'-TACGATCATAT-3' the correct complementary DNA strand is: A3'-TACGATCATAT-5' B3'-ATGCTAGTATA-5' C3'-AUGCUAGUAUA-5' D3'-GCATATACGCG-5' E3'-TATACTAGCAT-5'
Nucleotide 3 components: Pentose sugar; deoxyribose Phosphate group Nitrogenous base; 4 types : phosphate sugar base Join by condensation Stay the same Changes Contains nitrogen & carbon Ribose sugar in RNA Deoxyribose sugar in DNA Pentose sugar (5 Carbon atoms)
Nucleic Acids Polymer Individual unit called a (mono)nucleotide DNA is a type of nucleic acid – deoxyribonucleic acid.
Nucleic Acid The structure of DNA and RNA. 5C sugar The structure of a nucleotide P Organic base DNA and RNA are polymers of nucleotides.
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Nucleotides Specification: State that deoxyribonucleic acid (DNA) is a polynucleotide, usually double stranded, made up of nucleotides containing the bases.
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