1. AS_GSV Stations for Processing & Visualization of HR Medical Images Exit Course-AS1 Ltd. - Adaptive Medical Systems

2. AS_GSV Stations General Options 2D Processing & Visualization AS_GSV Stations Advantages Types of AS_GSV Stations Summary About Course-AS1 Ltd. Contents: - General Elements of AS_GSV Stations - Real Time Stream Processing - Real Time Zoned Processing

3. Course-AS1 Ltd. - Adaptive Medical Systems Founded in 1993 in Moscow, Russia. Focuses on developing new technologies and systems in the following areas: 2D processing for HR (High Resolution) medical images Specialized computer systems for radiology Multi-machine Parallel Calculations Chips-2D for processing HR images http:// www.course-as.com __ Course-AS1 Ltd. - Adaptive Medical Systems__ Office 427B, Business Park Rumiantsevo, MO, G.P. Moscow, 142784, Russian Federation. Mikael Abgaryan, Ph.D. Director E-mail: abgaryan@course-as. comTel/Fax: +7 (499) 550-5096 WEB: www.course-as.com +7 (499) 550-7682www.course-as.com www.course-as.ru (Full version)www.course-as.ru http:// www.course-as.ru

4. Professional, High Quality and Fast 2D Processing & Visualization for HR Medical Images Course-AS1 Ltd.

5. 2D - Visualization 2D Processing & Visualization for HR Medical Images High-Speed Hardware/Software 2D Conveyor based on Original Mathematical Processing of entire frame or in chosen Zones consisting of: Primary DICOM Images in Computer Memory The 16bit Conveyor for 2D Processing Visualization 2D Conveyor Hardware functions of visualization and some of processing elements in the graphic adapter (2D-Visualization) Scenario Processing Scenarios - sequence of types and processing cycles with a Parameter Settings Principle of Work 2D Processing & Visualization: 2D -Technology Sequence 16b software functions the 2D Software Conveyor for frame image processing (2D-Processing) Image Frame (DICOM Image) - the minimal part of information for 2D-Visualization and 2D-Processing Conveyor

6. General Elements of AS_GSV Stations Graphical DataBase – as Graphical Patients History The Navigator for Operation with DICOM files in Graphical DataBaseThe Navigator for Operation with DICOM files in Graphical DataBase Professional 2D Processing & Visualization for DICOM Systems PDF file Patient Data House and Graphical DataBasePatient Data House and Graphical DataBase Preprint Processing & Viewing for printing of processed imagesPreprint Processing & Viewing for printing of processed images Real Time Dynamic Stream 2D Processing (XA, RF) of 16b images (up to 60 fps of a format 1k*1k )Real Time Dynamic Stream 2D Processing (XA, RF) of 16b images (up to 60 fps of a format 1k*1k ) Real Time Dynamic Stream 2D Subtraction (DSA)Real Time Dynamic Stream 2D Subtraction (DSA) of 16b images (up to 30 fps of a format 1k*1k )of 16b images (up to 30 fps of a format 1k*1k ) Real Time Dynamic Zoned 2D Processing of 16b series and single framesReal Time Dynamic Zoned 2D Processing of 16b series and single frames

7. Radiological series (RF, DF, VF, CR, RG) Slides – Screen shots of processing Film 1 – Processing of 8b DICOM series Angiographic series (AS, XA, DSA) Tomography series (CT, MR, PT) Ultrasound series (US, EC, CD, DD) Slides – Screen shots of processing Film 1 – Primary 10b DICOM series Film 2 – DICOM representation of series Film 3 – Nonlinear Processing 10b DICOM of series Film 4 – DSA mode (Subtraction) Film 1 – Viewing 3D reconstruction of device CT Slides – Screen shots of processing Slides – Screen shots of processing Real Time Stream 2D Processing Series Frames (Modality) AS, XA, DSA, RF, DF, VF, CT, MR, PT, US, EC, CD, DD

8. Angiographic series (AS, XA, DSA) Radiological series (RF, DF, VF, CR, RG) Tomography series (CT, MR, PT) Slides – Screen shots of processing Film 1 – Processing in a circular zone Film 2 – Processing in an elliptic zone Slides – Screen shots of processing Film 1 – Processing CT series of a human body Slides – Screen shots of processing Film 2 – Processing CT series of a lower jaw Real Time Zoned 2D Processing Series and Single Frames (Modality) CR, RF, RG, MG, XA, CT, MR, SC

9. 16b Professional Tool for qualitative improvements of medical images PC Stations AS_GSV series for 2D Processing and Visualization of all types of DICOM files for: X-Ray diagnostics Angiographic research Computer Tomography Nuclear-Magnetic Resonance Tomography Ultrasonography Other kinds of diagnostics based on DICOM images AS_GSV Stations operations with DICOM files received from devices of different manufacturers: AS_GSV Stations General Options General Electric, Philips, Siemens, Picker, Kodak, Toshiba, Camtronics, InfiMed, Acuson, ATL, Hewlett-Packard ect.

10. Fine Quality Printing of the processed images on high resolution PC Printers without using of expensive DICOM printers The Authorized Access of users from any AS_GSV station connected to the Graphical DataBase for: visualization of DICOM primary data independent processing of DICOM series for visualization visualization of the series processed earlier by other users Interactive Visualization of the processing series for: displays on operational and viewing monitors displays in clinical and consultation facilities displays at symposiums and conferences Recording to Optical CD / DVD : recording on DVD-RAM in the Archive for Patient Data House processing results and primary DICOM files AS_GSV Stations General Options

11. AS_GSV Stations Advantages Real Time Dynamic Processing of primary Angiographic series, switching to DSA mode Exclusive Real Time Zone Processing of single or serial frames Professional High Speed Visualization based on the Scenarios Processing always only in the 16b resolution for Gray images (65536 gradation gray) Professional Visualization unattainable on PACS systems

12. High Speed and simplicity of high quality visualization Automatic creation of Processing Scenarios as a result of manipulations by users The Professional Intuitive 16b Real Time Tools for management & control of image processing Instant adjustment of conveyor processing and visualization based on created Scenarios Rapid response to change of processing parameters or conveyor elements AS_GSV Stations Advantages

13. Simplicity and high speed navigations Viewing and Grouping of DICOM files in a series with subsequent import in GDB All operations with DICOM files are conducted under the control of Graphical DataBase (GDB) Adjustable Options of GDB operations and access rights of users Unlimited number of users at simultaneous work with the same series AS_GSV Stations Advantages

14. Simplicity of realization of HIS/RIS clinical system Advantages of Systems based on the AS_GSV Stations Integration of AS_GSV Stations in PACS system as Professional Stations for 2D Processing Allocation of AS_GSV stations in a Network of 2D Professional Processing Images Scalability of Systems to include a range from one office or division up to clinical HIS/RIS Patient Data House volume minimization will be achieved by saving only DICOM primary data AS_GSV Stations can be used as Base Stations for newly created PACS systems

15. Base upon a 64b hardware platform – IBM IntelliStation A-Pro Opportunity to modernize by adding of PCI-X Professional Graphic Adapters with HR-monitors Essential Cost Reduction of diagnostic workstations and PACS systems Easy transition to a 64b Operational System without replacement of base computers Advantages of Systems based on the AS_GSV Stations Total Ownership Cost (TCO) reduction of medical diagnostic systems

16. Types of AS_GSV Stations Dual monitor AS_GSV-1k Station for dynamic frames up to 1k*1k for angiographic, radiological and tomographic research Dual monitor AS_GSV-2k Station for dynamic frames up to 2k*2k for angiographic and radiological research of the high resolution Dual monitor AS_GSV-4k2 Station for static frames larger than 2k*2k for radiological research of the super high resolution Three monitor AS_GSV-4k3 Station for static frames lager than 2k*2k for radiological research of the super high resolution and viewing rooms The Machine of AS_AVGBase DataBase (for 100-150 users) The Machine of AS_VRTBank - Temporary Data House (for 5-10 users or for a angiography) 1xOpteron 2.2GHz, 1GB DDR ECC Registered (up 2GB), 36GB System HDD SCSI, DVD-RW Plextor Ext, 1Gb Ethernet (up 10Gb InfiniBand), 19 RGB CRT 1600*1200*32b/(75-85)Hz, 21 RGB CRT 1600*1200*32b/(75-100)Hz for Images, Windows XP Professional & SP1, Library MIL v 5.0, Software AS_GSV-1k 2xOpteron 2.2GHz, 2GB DDR ECC Registered (up 4GB), 36GB System HDD SCSI, DVD-RW Plextor Ext, 1Gb Ethernet (up 10Gb InfiniBand), 19 RGB CRT 1600*1200*32b/(75-85)Hz, 21 RGB CRT 2048*1560*32b/(75-85)Hz for Images, Windows XP Professional & SP1, Library MIL v 5.0, Software AS_GSV- 2k 2xOpteron 2.2GHz, 2GB DDR ECC Registered (up 4GB), 36GB System HDD SCSI, DVD-RW Plextor Ext, 1Gb Ethernet (up 10Gb InfiniBand), 19 RGB CRT 1600*1200*32b/(75-85)Hz, 21 B&W CRT 2560*2048*32b/(50-75)Hz for Images, Windows XP Professional & SP1, Library MIL v 5.0, Software AS_GSV- 4k2 2xOpteron 2.2GHz, 2GB DDR ECC Registered (up 4GB), 36GB System HDD SCSI, DVD-RW Plextor Ext, 1Gb Ethernet (up 10Gb InfiniBand), 19 RGB CRT 1600*1200*32b/(75-85)Hz, 2x21 B&W CRT 2560*2048*32b/(50-75)Hz for Images, Windows XP Professional & SP1, Library MIL v 5.0, Software AS_GSV- 4k3 1xOpteron 2.2GHz, 2GB DDR ECC Registered (up 4GB), 36GB System HDD SCSI, 400GB RAID-0 SATA (up 800GB), 1Gb Ethernet (up 10Gb InfiniBand), Windows NT 4.0 & SP6. 2xOpteron 2.2GHz, 4GB DDR ECC Registered (up 16GB), 2x36GB System HDD SCSI, 250GB SATA HDD (for Archive), 147GB RAID-1 U320 SCSI (for database), 4xDVD-RAM 9GB, DVD-RW Plextor Ext, 1Gb Ethernet (up 10Gb InfiniBand), 19 RGB CRT 1600*1200*32b/(75-85)Hz, Windows NT 4.0 & SP1, Library MIL v 5.0, Software AVGBase-2k04.

17. Summary Unprecedented quality of images for reliable diagnostics! Unprecedented speed of processing and visualization of medical images Optimized Total Cost Ownership of AS_GSV Stations of a professional class Professional Stations 2D Processing & Visualization - Perfect Tool for Professionals! Exit Medical images processing and visualization management simplicity