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How Cells Divide Chapter 10. Bacterial Cell Division Binary Fission FtsZ protein.

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Presentation on theme: "How Cells Divide Chapter 10. Bacterial Cell Division Binary Fission FtsZ protein."— Presentation transcript:

1 How Cells Divide Chapter 10

2 Bacterial Cell Division Binary Fission FtsZ protein

3 Eukaryotic Chromosomes Chromosome Numbers Vary Made of Chromatin

4 Some Vocab Karyotype Haploid Diploid Homologue Chromatids

5 Overview of the Cell Cycle G1 S G2 M C G0

6 Interphase G1, S, G2

7 Mitosis Prophase Prometaphase Metaphase Anaphase Telophase

8 Prophase Condensation of Chromosome Contintues Spindle apparatus –Asters Nuclear envelope disassembles

9 Prometaphase Micrtubules attach to the kinetochore Chromosomes begin to move toward the equator of the cell

10 Metaphase Chromosomes are aligned at the equator of the cell called the metaphase plate Chromosomes are attached to opposite poles and are under tension

11 Anaphase Proteins holding centromeres of sister chromatids are degraded, freeing individual chromosomes Chromosomes are pulled to opposite poles Spindle poles move apart

12 Telophase Chromosomes are clustered at opposite poles and decondense Nuclear envelopes reform around chromosomes Golgi complex and ER re-form

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14 Cytokinesis Plant vs Animal

15 Control of the Cell Cycle Irreversible points Checkpoints

16 MPF Nondividing cells can be stimulated into division by MPF MPF activity changes throughout the cell cycle It is cyclin pluc cdc2 (aka Cdk) –What is a kinase?

17 Three main Checkpoints G1/S G2/M Spindle Checkpoint (APC) Figure 10.20

18 Growth Factors Trigger intracellular signaling systems RTKs and MAP cascades

19 G0 Phase Dormant Liver vs Intestinal Lining Cells

20 Cancer Tumor Suppressor genes- p53, Rb Oncognes-ProtoOncogenes


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