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Energy and Metabolism Chapter 6. Energy The capacity to do work Potential vs Kinetic.

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Presentation on theme: "Energy and Metabolism Chapter 6. Energy The capacity to do work Potential vs Kinetic."— Presentation transcript:

1 Energy and Metabolism Chapter 6

2 Energy The capacity to do work Potential vs Kinetic

3 How is it measured? Heat Calorie Joule = Calories Most energy is provided by the sun

4 Oxidation-reduction reactions AKA redox OilRig

5 Thermodynamics Energy changes First Law of Thermodynamics Second Law of Thermodynamics –How does this apply to humans?

6 Free Energy The energy Available to do work Delta G= Delta H- TDelta S H= enthalpy which is the energy contained in the chemical bonds of a substance T= temperature kelvin S= entropy or the energy unavailable due to disorder

7 Endergonic vs Exergonic If Positive Delta G then the reaction is endergonic If Negative Delta G then the reaction is evergonic

8 Activation Energy Spontaneous Chemical Reactions Require activation energy Catalysts

9 You down with ATP???? The energy currency of cells Hydrolysis drives endergonic reactions ATP cycles continously

10 Enzymes Biological Catalysts Ligand vs Substrate Active Sites Are they all proteins?

11 MultiEnzyme Complex Sounds familiar…. 3 advantages –Increases the frequency with which the enzyme collides with the substrate –Eliminates the possibility of unwanted reactions –All reactions take place within the complex can be controlled as a unit

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13 Factors Affecting Enzyme Function Temperature pH Inhibitors and Activators –Allosteric Site Cofactors

14 Inhibitors and Activators

15 Cofactors and Conenzymes Assists enzyme function Cofactors are usually metal ions Coenzyme- a nonprotein organic molecule- can serve as an electron acceptor in a redox reaction

16 Metabolism Anabolic- use energy Catabolic- need energy Biochemical Pathways –Evolution of BPs

17 Feedback Inhibition Regulates Biochemical Pathways Why Important?


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