2Cortitrol: Dietary Supplement Cortitrol is a supplement that assists you in dealing with difficult situations.Take Control!
3Introducing Cortitrol What is Cortitrol?Introducing CortitrolCortitrol is a unique dietary supplement that addresses the symptoms of a fast-paced lifestyle.Cortitrol’s ingredients balance the level of cortisol in the body.
4What is Cortisol? Background Cortisol is a hormone produced by your body in response to difficult events.The occasional release of cortisol is essential to respond to emergency situations. Too frequent release of cortisol can lead to health problems.
5What is Cortisol? Cortisol The role of Cortisol in Health and Longevity.
6What is Cortisol? Today’s Health Demons 1980’s = Cholesterol Early 1990’s = Free Radicals / AntioxidantsLater 1990’s = Insulin / Blood Sugar2000’s = Cortisol
7What is Cortisol? Cortisol in the Media More Than 1,000 News Articles Over the Past Year!Time, Washington Post, Reader’s Digest, etc1st International Symposium on Cortisol, Stress and HealthMay 2002New Book: The Cortisol Connection...Why Stress Makes You Fat & Ruins Your Health…And What You Can Do About ItPublished September 2002
8What is Cortisol? The body’s primary stress hormone: “Fight-or-Flight” responseRequired by the body for survivalRegulates inflammation, carbohydrate metabolism, cardiovascular function, etc…BUT too much of cortisol for too long leads to problems:Repeated exposure to stressful situations (personal, family, work)Modern stressors do not permit “fight-or-flight”Stress hormones do not dissipateStress can lead to degenerative health consequences
9What is Cortisol? STRESS ACUTE STRESS brief normal circadian rhythm adaptiveCHRONIC STRESSprolonged & repeateddisrupted circadian rhythmmaladaptive
10Repeated Stress Elevates Cortisol What is Cortisol?Repeated Stress Elevates Cortisol
11What is Cortisol?The Relationship Between Elevated Cortisol and Stress Related ConditionsScientific Evidence
12Impact of Elevated Cortisol in: What is Cortisol?Impact of Elevated Cortisol in:Obesity & Metabolic SyndromeHigh cortisol secretion = abdominal fat = illnessSuppressed ImmunityAssociated with low counts of white blood cellsAcute psycholsocial and sleep deprivation stress disrupts skin barrier homeostasisChanges due in part from increased cortisol levels.
13Impact of Elevated Cortisol in: What is Cortisol?Impact of Elevated Cortisol in:AppetitePeople who diet have high cortisol secretionBone MetabolismHigh cortisol secretion = dietary restraint = implications for bone health
14What is Cortisol? Other Research Additional research has also identified many other health issues associated with elevated cortisol levels.
15Stress and Health Care Costs Work DemandsIncreasedHealthCare Costs$$$CortisolReactivityJob ControlGanster et al. Journal of Applied Psychology, 2001, 86,
16Cortisol Levels are Elevated in… What is Cortisol?Cortisol Levels are Elevated in…Chronic StressSleep DeprivationDieting / Restrained EatingAdults who need to control cortisol levels:Get less than 8 hours sleepFeel run-down, lack of mental focusLimit caloric intake to lose weightOften in difficult situations
17The Market: Prevalence of Chronic Stress 80% of workers report feeling stress on the jobStress contributes to half of all illnesses in the US70-80% of all doctor visits are stress-related>50% all deaths between the ages of 1 and 65 result from stressSources: U.S. Center for Disease Control; World Health Organization; Gallup Poll “Attitudes in the American Workplace”
18The Market: Prevalence of Chronic Stress Generalised anxiety disorder affects an estimated 183 million people worldwidePeople who live in a high state of anxiety are 4.5 times more likely to die prematurelySources: U.S. Center for Disease Control; World Health Organization; Gallup Poll “Attitudes in the American Workplace”
19The Solution: Cortisol Management You can control cortisol levels via:Stress Management TechniquesMeditation, coping strategies, etc…ExerciseOptimal NutritionLifePak and Tegreen 97Dietary SupplementsCortitrol, LifePak and Tegreen 97
20Common Anti-Stress Solutions ValerianKava KavaMelatoninTyrosineNone of these supplements directly address cortisol control
21Cortitrol What is Cortitrol? Enhances feelings of well-being and control in response to difficult situationsImproves performance and increased vigour throughout the dayGenerates better mental concentration and focusSupports weight maintenance efforts
22Cortitrol: AdvantageUnique patent-pending dietary supplement that supports healthy cortisol levelsProprietary (company owned) blend & comprehensive ingredientsBalances cortisol levelsContains a proprietary, all-natural form of theanine extractManufactured according to the highest TGA standards and the Pharmanex 6S Quality Process
23Cortitrol: Proprietary Formula Comprehensive, proprietary formula that addresses direct cortisol modulationScientifically validated ingredients in clinically significant dosagesMagnolia BarkPhosphatidylserineEpimediumL-Theanine
25OPTIMAL HEALTH FOUNDATION BLOCKS FibreNetOptimum OmegaJoint FormulaBioGinkgo 27/7LifePak/CortitrolTegreen 97OPTIMAL HEALTH FOUNDATION BLOCKSInner HealthMemoryProtectionJungamalsLifePak for Kids
26Cortitrol: Recommended Usage Take two (2) tablets with your evening meal. For optimal results take an additional one (1) tablet with your morning meal
27Cortitrol: And LifePak Promote Cortitrol to be taken with LifePak.Why?Optimal nutritional health which includes vitamin C, B1, B2, Calcium, Magnesium, Pantothenic acid, and Pyridoxine, combined with cortisol modulation.
29Cortitrol: Product Support Clinical Studies & references on individual ingredients in the formulaPharmanex Web Site – orPubMed Web Site -Also on our web site:Product InformationQ&AsTraining MaterialGeneral Health Facts
30Cortitrol: Q&A Why does Cortitrol come in tablet form? Better cost valueIs there a difference b/w Epimedium brevicornum and koreanum?No. Both are from two similar plants but have the same efficacy, the same active component. TGA preferred we use brevicornum.
31Cortitrol: Q&A Are there any known drug interactions? If you are pregnant or lactating, have a known medical condition or are taking a prescription medication, or are allergic to any component of this product, consult a physician prior to use.Will coffee or caffeine negate the effectiveness of Cortitrol?No, coffee or caffeine will not "negate" the effects of Cortitrol; rather, Cortitrol would be expected to permit the "energy" benefits of coffee but without the "jittery" side effects.
32Cortitrol: Q&AThere are several hormones regarding stress besides cortisol. Why is Pharmanex focusing on cortisol and not the others?Cortisol is the primary stress hormone. When we experience stress, cortisol is the stress hormone that remains elevated the longest.Will Cortitrol make it hard for me to sleep at night?In some cases, Cortitrol users have experienced increases in energy levels and makes them feel more alert. We suggest taking Cortitrol in the morning, rather than the evening, which seems to help.
33Cortitrol: Q&A What is the normal range of cortisol levels? The "normal" range for blood cortisol levels is fairly wide, 6-23 mcg/dl, but these levels can vary tremendously in response to stress, illness, and even following meals.
34Cortitrol: Q&A Any drug or medical interactions? We have found that people are able to take Cortitrol with most medications. Just like all of our products, however, we do not know all the potential interactions with Cortitrol. As always, we must recommend that they discuss this product with their doctor or pharmacist who knows their prescription history.If you are pregnant or lactating, or taking a prescription medication, have a known medical condition, or allergic to any component of this product, please consult a physician prior to use. Consult a physician if you are taking prescription "anti-stress" medications such as anxiolytics, sedatives, or hypnotics. Consult a physician if you are taking other CNS depressants, tricyclic antidepressants, anti-epileptics, muscle relaxants, anticoagulants, corticosteroids and quinalone antibiotics. Use of l-theanine concomitantly with chemotherapeutic agents must be done under medical supervision. L-theanine may enhance the effects of doxorubicin, idarubicin, adriamycin, and picarubicin and may ameliorate some of their side effects (PDR for Nutritional Supplements 2001, Sadzuka 1996, Sugiyma 1998, 1999). This supplement should be discontinued two weeks prior to surgery.
35Cortitrol: Marketing Material Pharmanex Brochure (5 pk) $8.00Pharmanex Cap (ea) $12.95Power of Wisdom & Knowledge Video (ea) $7.50Pharmanex Pill Box (ea) $3.00Cortitrol Brochure (5 pk) $4.50The Cortisol Story Brochure (5 pk) $9.50Stress Test Card (5 pk) $11.00
36Cortitrol Summary Balances cortisol levels Proprietary blend of ingredients shown to have direct effects on cortisol levelsProprietary l-theanine ingredientToday’s answer to the fastest growing health demon!
37Cortitrol Next Steps Order Today! Spread the word Ensure all Distributors and Customers benefit from purchasing through ADP.