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What I Do Donald Giacherio, Ph.D. Clinical Associate Professor of Pathology Director, Chemistry Section Laboratories Director, Specimen Processing Director,

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Presentation on theme: "What I Do Donald Giacherio, Ph.D. Clinical Associate Professor of Pathology Director, Chemistry Section Laboratories Director, Specimen Processing Director,"— Presentation transcript:

1 What I Do Donald Giacherio, Ph.D. Clinical Associate Professor of Pathology Director, Chemistry Section Laboratories Director, Specimen Processing Director, Ancillary Site Testing Services

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3 Direct the Operations of the Chemistry Section Laboratories Automated Chemistry Special Chemistry Drug Analysis and Toxicology Immunology Point of Care Testing

4 Key Personnel Sue Stern -- Administrative Manager Eric vasBinder -- Automation Supervisor Mara Williams -- Special Chemistry Supervisor Sheridan Mattson -- Toxicology Supervisor Linda Thomas -- Immunology Supervisor Melanie Herbert -- Evening and Midnight shift Denise Twarkowski -- Point of Care

5 2005200620072008 2009 2010 CDM’s1,9555862,140,6602,340,5602,474,9902,541,6722,653,013 CDM growth185,072199,900134,43066,682111,341 % CDM growth 9.46 %9.34 %5.74 %2.69 %4.38 % Expense $8,232,4348,082,1939,145,8529,822,10010,186,81511,179,205 $ per CDM $ 4.31$3.78$ 3.91$3.96$ 4.01$ 4.21 FTE 58 60 61 62 64 66 Chemistry Laboratory Financials

6 Limited budget growth despite significant new test growth CVC OR Lab Quantiferon TB testing started Cotinine Hemoglobinopathy Evaluation Troponin I testing in Emergency Department Continued growth of transplant program support Psychiatry Addiction Treatment Program support – Ethyl glucuronide, GC-MS drug screens, Oxycodone, Buprenorphrine, Methadone Virus serology testing moved from Microbiology – EBV, HSV, CMV, Toxo, VZV, Mumps, Measles, H. pylori

7 Chemistry Laboratory Services 3500 tubes/day Chemical Laboratory automation line volume 8 million tests/year 24 x 7 service

8 Our labcell configuration 3 - Advia 2400’s 2 - Sample managers 2 - Centrifuge XL’s 2 - Decapper modules 3 - Advia Centaur’s

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12 “Lean” in Chemistry Redesign of sample handling area of the lab Monitoring of STAT sample turnaround times Visual cues system Mail in immunosuppressant samples TAT for inpatient immunosuppressant drugs Selected as one of 11 health system wide areas for new “Lean Implementation Teams” training of all techs

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14 POCT at University Hospitals Whole Blood Glucose: 280 meters, perform 600,000 patient, tests per year Coag tests: 8 meters in OR’s of Main, Mott, and CVC for PT, aPTT, ACT Blood Gas / electrolyte analyzers in OR’s and ED Creatinine on i-STAT for three Interventional Radiology sites

15 Intra-operative PTH: Analyzer moved to OR for parathyroidectomies: 300 cases last year. Measure PTH at baseline, 10 min, and 15 min post excision.

16 Ancillary Site Laboratories: Key Personnel Mary Lou Erber -- Administrative manager Theo Jones Denise Brown Suzanne Clark Cindy Stutzman Annette Collino

17 POCT at Health Care Centers Hemoglobin A1C: 26 DCA Vantage analyzers at 14 sites, perform 30,000 tests per year Lipid profile: Cholestech LDX at Domino Farms, CVC Blood draw station Blood gas / Electrolytes: i-STAT at Kellogg Eye Center, EAA Surgery Center, Livonia Surgery Center, Canton Infusion Center

18 Specimen Processing 9000 samples per weekday distributed to labs Sendout testing Key Personnel – Harry Neusius – Bonnie Grayson – Beth Lawless – Renee Stoklosa – Mary Deis – Michael Horgrow – Lakesha Holloway

19 Research 7.5 % effort on NIDDK funded Michigan Diabetes Research and Training Center Martin Myers, Ph.D. and William Herman, M.D. Direct Chemistry Core Lab on 6 th floor Brehm Bldg Lab provides service for over 45 diabetes related projects, performing 18,000 tests / year Assays for Lipids, Hgb A1c, Glucose, Insulin, C-peptide, Leptin, Adiponectin, Ghrelin, PAI-1, Luminex cytokine profiles

20 Research Development of POC assay for Apo B and Apo A1 With Alan Hunt, Ph.D. and Robert Brook, M.D. Apo B is major protein of LDL, Apo A1 is the major protein of HDL Work on microfluidic cartridge device using fluorescence polarization immunoassay. $30,000 MICHR award, $95,000 seed money from a venture capital company, Net Scientific

21 Teaching Coordinate rotation of Pathology Residents through the Chemistry Lab Review Hemoglobinopathy evaluations Review 2 nd trimester maternal serum prenatal screen results (Quad Test) Meet daily with residents to review lab issues

22 So Kurt, who do you think the Lions should draft this week? Anthony Costanzo, OT, Boston College Prince Amukamara, CB, Nebraska

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