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1 Thank You This PowerPoint document contains the images that you requested. Copyright Notice All Online Service materials, including, without limitation, text, pictures, graphics and other files and the selection and arrangement thereof are copyrighted materials of Ovid or its licensors, all rights reserved. Except for the Authorized Use specified above, you may not copy, modify or distribute any of the Online Service materials. You may not "mirror" any material contained on this Online Service on any other server. Any unauthorized use of any material contained on this Online Service may violate copyright laws, trademark laws, the laws of privacy and publicity and communications regulations and statutes.

2 Copyright © 2009 Massachusetts Medical Society. All rights reserved. Published by Massachusetts Medical Society. 2 Table 1 Long-Term Outcome Associated with Early Repolarization on Electrocardiography. Tikkanen, Jani; Anttonen, Olli; Junttila, Juhani; Aro, Aapo; Kerola, Tuomas; Rissanen, Harri; Reunanen, Antti; Huikuri, Heikki New England Journal of Medicine. 361(26): , December 24, Table 1 Characteristics of the Subjects at Baseline.

3 Copyright © 2009 Massachusetts Medical Society. All rights reserved. Published by Massachusetts Medical Society. 3 Table 2 Long-Term Outcome Associated with Early Repolarization on Electrocardiography. Tikkanen, Jani; Anttonen, Olli; Junttila, Juhani; Aro, Aapo; Kerola, Tuomas; Rissanen, Harri; Reunanen, Antti; Huikuri, Heikki New England Journal of Medicine. 361(26): , December 24, Table 2 Unadjusted and Adjusted Relative Risk of Death, According to J-Point Elevation.

4 Copyright © 2009 Massachusetts Medical Society. All rights reserved. Published by Massachusetts Medical Society. 4 Figure 1 Long-Term Outcome Associated with Early Repolarization on Electrocardiography. Tikkanen, Jani; Anttonen, Olli; Junttila, Juhani; Aro, Aapo; Kerola, Tuomas; Rissanen, Harri; Reunanen, Antti; Huikuri, Heikki New England Journal of Medicine. 361(26): , December 24, Figure 1 Kaplan-Meier Curves for Death from Cardiac Causes and from Arrhythmia in Subjects with J-Point Elevation. Subjects with J-point elevation of more than 0.2 mV in the inferior leads on standard 12-lead electrocardiography had a markedly elevated risk of death from cardiac causes, as compared with those without an early-repolarization pattern (<0.1 mV), with an unadjusted relative risk of 3.52 (95% confidence interval [CI], 2.18 to 5.68; P<0.001) (Panel A). The same subjects had an unadjusted relative risk of death from arrhythmia of 3.94 (95% CI, 1.96 to 7.90; P<0.001) (Panel B).

5 Copyright © 2009 Massachusetts Medical Society. All rights reserved. Published by Massachusetts Medical Society. 5 Figure 2 Long-Term Outcome Associated with Early Repolarization on Electrocardiography. Tikkanen, Jani; Anttonen, Olli; Junttila, Juhani; Aro, Aapo; Kerola, Tuomas; Rissanen, Harri; Reunanen, Antti; Huikuri, Heikki New England Journal of Medicine. 361(26): , December 24, Figure 2 Baseline Electrocardiograms of Two Male Subjects with J-Point Elevation of More Than 0.2 mV in the Inferior Leads. In two subjects with J-point elevation of more than 0.2 mV in the inferior leads, Subject 1 has a slurred elevation (arrows) and Subject 2 has a notched elevation (arrows). Both subjects died from arrhythmia during the follow-up period.

6 Copyright © 2009 Massachusetts Medical Society. All rights reserved. Published by Massachusetts Medical Society. 6 Table 3 Long-Term Outcome Associated with Early Repolarization on Electrocardiography. Tikkanen, Jani; Anttonen, Olli; Junttila, Juhani; Aro, Aapo; Kerola, Tuomas; Rissanen, Harri; Reunanen, Antti; Huikuri, Heikki New England Journal of Medicine. 361(26): , December 24, Table 3 Adjusted Relative Risk of Death from Cardiac Causes in the Secondary Analysis.


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