Presentation is loading. Please wait.

Presentation is loading. Please wait.

By: Nour-Eldin Mohammed Neuroradiology Congenital Malformation of CNS.

Similar presentations


Presentation on theme: "By: Nour-Eldin Mohammed Neuroradiology Congenital Malformation of CNS."— Presentation transcript:

1 By: Nour-Eldin Mohammed Neuroradiology Congenital Malformation of CNS

2 Callosal Dysgenesis Definitions: One or all segments of CC absent (if partial, body remains) CC segments front to back: Lamina rostralis (unmyelinated) Rostrum (myelinated) Genu Body Splenium

3 Callosal Dysgenesis General Features: Axial: Parallel lateral ventricles Coronal: "Trident" anterior horns resemble "viking helmet" or "moose head“ Location: Midline anomaly Size: CC remnants vary in size, shape, Remnant may be paper thin or bulbous

4 Callosal Dysgenesis Radially arrayed gyri "point to" 3rd ventricle Absent Cingulate Gyrus

5 Callosal Dysgenesis Lateral ventricles are key to diagnosis: Parallel (non-converging) Widely separated Occipital horns often dilated (colpocephaly) Pointed frontal horns

6 Callosal Dysgenesis Coronal T2WI MR shows agenesis of the corpus Callosum trident shaped lateral ventricles vertical hippocampi (open arrow), enlarged, "keyhole" shaped temporal horns and Probst bundles (curved arrow).

7 Callosal Dysgenesis Axial NECT with widened "windows" shows colpocephaly, calcified (arrow) midline lipoma that extends through choroid fissures into lateral ventricles (open arrows). Axial TlWI MR shows parallel ventricles, colpocephaly, and a midline lipoma. Note lipoma (arrow) protruding into the lateral ventricles.

8 Callosal Dysgenesis Coronal T2WI MR in fetus shows trident shaped lateral ventricles, agenesis of Cc "Probst bundle" (curved arrow) vertical hippocampus (arrow).

9 Differential Diagnosis of Callosal Dysgenesis Differential Diagnosis of Callosal Dysgenesis Partial Absence of Callosal Dysgenesis

10 Destruction of CC Differential Diagnosis of Callosal Dysgenesis Differential Diagnosis of Callosal Dysgenesis Surgery (callosotomy),trauma (Acquired interhemispheric disconnection syndrome) Hypoxic ischemic encephalopathy (HIE), infarcts Metabolic

11 Differential Diagnosis of Callosal Dysgenesis Differential Diagnosis of Callosal Dysgenesis Stretched Corpus Callosum (e.g.: Hydrocephalus) Thinned CC but all parts present Severe hydrocephalus often present

12 Lipoma Definitions Mass of mature non-neoplastic adipose tissue CNS lipomas are congenital malformations, not true neoplasm

13 Lipoma General Features Best diagnostic clue: Well-delineated lobulated extra-axial mass with fat attenuation/intensity Location : Midline location common 80% supratentorial : % interhemispheric fissure (over corpus callosum; may extend into lateral ventricles, choroid plexus) % suprasellar (attached to infundibulum, hypothalamus) % pineal region (usually attached to tectum) 20% infratentorial Cerebellopontine angle (may extend into lAC, vestibule) Uncommon: Jugular foramen, foramen magnum

14 Lipoma (a small interhemispheric lipoma (arrows) above the corpus callosum, found incidentally at MR imaging in this patient with headache. Sagittal Tl WI MRSagittal Tl WI MR with fat-saturation

15 Lipoma Sagittal TlWI MR shows a well- circumscribed high signal lesion in the pineal region (arrow).The patient was asymptomatic. Axial gross pathology shows a quadrigeminal lipoma (arrow)

16


Download ppt "By: Nour-Eldin Mohammed Neuroradiology Congenital Malformation of CNS."

Similar presentations


Ads by Google