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Autologous adipose stem cells and polylactide discs in the replacement of the rabbit temporomandibular joint disc by Katja Ahtiainen, Jari Mauno, Ville.

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Presentation on theme: "Autologous adipose stem cells and polylactide discs in the replacement of the rabbit temporomandibular joint disc by Katja Ahtiainen, Jari Mauno, Ville."— Presentation transcript:

1 Autologous adipose stem cells and polylactide discs in the replacement of the rabbit temporomandibular joint disc by Katja Ahtiainen, Jari Mauno, Ville Ellä, Jaana Hagström, Christian Lindqvist, Susanna Miettinen, Timo Ylikomi, Minna Kellomäki, and Riitta Seppänen Interface Volume 10(85): August 6, 2013 ©2013 by The Royal Society

2 (a) The excised TMJ disc next to the ASC disc implant. Ahtiainen K et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

3 The relative expression levels of (a) aggrecan, (b) type I and (c) II collagen of the ASC discs after one week pre-culture prior to implantation measured by qRT-PCR. Ahtiainen K et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

4 CBCT images of the operated TMJ joints in the six- and 12-month groups represented as (a,e) axial and (c,g) coronal views as well as sagittal views of the (b,f) right and (d,h) left TMJs treated with control and differentiated ASC discs, respectively. Ahtiainen K et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

5 The sagittal histological sections of the TMJ area stained with Masson's trichrome. Ahtiainen K et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

6 (a,b) The remnants of the ASC discs stained with haematoxylin–eosin of the control and (c,d) differentiated ASCs discs after (a,c) six and (b,d) 12 months of implantation. Ahtiainen K et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society


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