Case # 2 Capsule endoscopy findings: Submucosal mass Ulceration on surface with central umbilication (arrow) Blanching of mucosa A subsequent CT scan of the abdomen/pelvis performed…
Computerized Tomography of Abdomen: Illustrating metastatic liver lesions.
Case Report Liver biopsy performed Stromal tumor on histology CD 117/c-kit positive
Case Report Diagnosis: Metastatic gastrointestinal stromal tumor (GIST) The patient started on imatinib Disease has been stable
Case Report Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal malignancy in the gastrointestinal tract Pathogenesis based on gain-of-function mutations in the c-kit proto-oncogene Tyrosine kinase inhibitor imatinib mesylate (Gleevac™) has had a major impact on treatment outcomes and survival for these patients with GIST
Case Report Capsule endoscopy identified the primary site in the gastrointestinal tract when other methods failed. Findings explained the gastrointestinal bleeding and intermittent bowel obstructions. Unfortunately, metastatic disease was already present by the time a diagnosis was made.