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Will Penny Wellcome Centre for Neuroimaging at UCL MethodsPhysics Attention LanguageMemory Emotion Vision fMRIMEG Theoretical Neurobiology.

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Presentation on theme: "Will Penny Wellcome Centre for Neuroimaging at UCL MethodsPhysics Attention LanguageMemory Emotion Vision fMRIMEG Theoretical Neurobiology."— Presentation transcript:

1 Will Penny Wellcome Centre for Neuroimaging at UCL MethodsPhysics Attention LanguageMemory Emotion Vision fMRIMEG Theoretical Neurobiology

2 Statistical Parametric Mapping (SPM) Realignment Smoothing Normalisation General linear model Statistical parametric map Image time-series Parameter estimates Design matrix Template Kernel Random Field Theory p <0.05 Statisticalinference

3 Neural state equation : Electric/magnetic forward model: neural activity  EEG MEG LFP (linear) Neural model: 1 state variable per region bilinear state equation no propagation delays Neural model: 8 state variables per region nonlinear state equation propagation delays fMRI MEG inputs Hemodynamic forward model: neural activity  BOLD (nonlinear) Dynamic Models of Brain Interactions

4 Dynamical Neural Network Model for fMRI u2u2 u1u1 z1z1 z2z2 u2u2 z1z1 z2z2 u1u1 a 11 a 22 c a 12 a 21 b 21

5 Opportunities UCL CoMPLEX Computer Science Engineering Physics Statistics


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