1. Cri-Du-Chat Syndrome
“Cry Of The Cat”

2. Type of Genetic disorder
Cri-Du-Chat is a disorder caused by a deletion in the chromosome 5.

3. Chromosomal Graphic

4. Symptoms
As an infant the child’s cry is described as sounding like a cat.
Low birth weight and slow growth
Lower ears.
Partial webbing or fusing of fingers or toes
Single line in the palm of the hand
Slow or incomplete development of motor skills
Small head and jaw
Mental Retardation

5. Diagnosis
Cri-Du-Chat is diagnosed by the obvious symptom of the cat like cry, most likely after birth in the hospital. The shortened chromosome 5 may also be seen on a chromosomal analysis. As well as by noticing more than one physical symptom.

6. Prognosis
Depending on the level of seriousness in the diagnosis, most people afflicted may have an average life with a normal life span. Many may have a more severe case mental retardation and will not be able to function in society or care for themselves.

7. Treatment
No known treatment has been developed for this disorder, although some organizations are now studying the disorder, prevention and treatment.

8. Current Research
Researchers are studying the genes to find exactly which parts of chromosome 5, that are deleted, are connected to a symptom.

9. Genetic Counseling
Genetic Counseling is usually pressed upon two parents who have a history of the disease as they carry a dysfunctional chromosome 5 as well.

10. Children With Cri-Du-Chat

11. Story
Brooke born at 5 Pounds 4 ¾ Ounces, was diagnosed within a week of birth. She cannot walk as of yet but is very social and can use her Gait Trainer to walk. She’s already overcome many difficulties of this disease and can express herself and form sentences, something many children at her age are barely beginning to develop the skills to.

12. Credits http://www.fivepminus.org/about.htm
ri-du-chat-syndrome/overview.html
htm