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Performance measures Morten Nielsen, CBS, Department of Systems Biology, DTU.

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Presentation on theme: "Performance measures Morten Nielsen, CBS, Department of Systems Biology, DTU."— Presentation transcript:

1 Performance measures Morten Nielsen, CBS, Department of Systems Biology, DTU

2 Performance measures Meas Pred

3 Pearsons’ correlation coefficient

4 Performance measures Accuracy of prediction method Sort

5 Evaluation of prediction accuracy TPFN AP AN TNFP

6 Matthews correlation- Threshold of 0.5 False positive True positive True negative False negative

7 Matthews correlation- Threshold of

8 Performance measure – Roc curve False positive True positive True negative False negative

9 Performance measure – Roc curve False positive True positive True negative False negative

10 ThresholdTPFNTP/(TP+FN)FPTNFP/(FP+TN) > > > > > AUC = 0.5 AUC = 1.0 ROC curves

11 AUC (area under the ROC curve)

12 Summary MCC and PCC Random = 0.0 Perfect = 1.0 (or -1) ROC (AUC) Random = 0.5 Perfect = 1 (or 0)


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