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© life_edu Lecture 26 Part Ic. Animal and Human Cloning and Genetic Engineering Issues in Biotechnology: The Way We Work With Life Dr. Albert P. Kausch.

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Presentation on theme: "© life_edu Lecture 26 Part Ic. Animal and Human Cloning and Genetic Engineering Issues in Biotechnology: The Way We Work With Life Dr. Albert P. Kausch."— Presentation transcript:

1 © life_edu Lecture 26 Part Ic. Animal and Human Cloning and Genetic Engineering Issues in Biotechnology: The Way We Work With Life Dr. Albert P. Kausch life edu.us Medical Biotechnology

2 Issues in Biotechnology: Biotechnology, Our Society and Our Future OnCampus Live BCH 190, MIC 190, AFS 190, NRS 190, PLS 190 OnLine BCH 190 A Sweeping General Survey on Life and Biotechnology A Public Access College Course The University of Rhode Island Kimberly Nelson Issues in Biotechnology: The Way We Work With Life Dr. Albert P. Kausch life edu.us

3 © life_edu A Sweeping General Survey on Life and Biotechnology The University of Rhode Island Issues in Biotechnology: The Way We Work With Life Dr. Albert P. Kausch life edu.us BCH 190 Section II. The Applications of Biotechnology

4 Where is DNA in a cell? All of the information for each protein in a cell is in it’s DNA All of the information that codes for a complete organism is in DNA

5 Cloning Animals Cloning and Genetic Engineering in Animals

6 Genetically Engineered Animals Cloning and Genetic Engineering in Animals

7 How to Clone

8 Nuclear transfer procedures

9 This shows: All of the information that codes for an organism is in it’s DNA All of the DNA is the same in every cell DNA is located in the nucleus of the cell An Organism can be cloned by transferring it’s DNA to an egg cell

10 PromoterCoding SequenceTerminator Could we Genetically Engineer Cloned Animals? Controlled expression “making protein” Your favorite gene Vaccines Antibodies High Value Proteins Spider Silk in Goats Milk Stop transcription Message stability

11 Genetically Modified somatic nuclei could be implanted into unfertilized eggs to create a genetically modified clone

12 Genetically Modified somatic nuclei could be implanted into unfertilized eggs to create a genetically modified clone Transgenics and Cloned Animals

13 What is cloning? A process whereby all members are directly descended (asexually) from a single organism by……(various ways) Demonstrates that all the information required for an organism and its development are in the a single cell

14 Where is DNA in a cell? All of the information for each protein in a cell is in it’s DNA All of the information that codes for a complete organism is in DNA

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16 Principle All cells are derived from a zygote All have the same genetic makeup All have the potential to develop into an individual

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22 UCONN Clones

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24 Many animals can now be cloned sheep cattle porcine mice rats mules frogs primates? And Genetically Engineered

25 Primates 2012 And Genetically Engineered Many animals can now be cloned

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27 Issues in Biotechnology The ‘cloning’ of plants was demonstrated by Steward in 1958 at Cornell Univ. showing that plants could be grown back from a single cell. This ability is called “totipotency” and like the more recent examples of animal cloning, demonstrates: (A) that all biological scientists are unethical and fraudulent (B) that all of the DNA that codes for an entire organism is in every cell of that organism (C) Steward belonged to the group that called themselves the ‘Raeliens’ (D) the necessity to ban all types cloning (E) that the theory of evolution must be wrong

28 Could we Genetically Engineer Humans? Your favorite gene Insulin Cancer Anti-Oncogenes Parkinson’s Huntington’s SCID Beyond Therapy??? PromoterCoding SequenceTerminator Controlled expression “making protein” Stop transcription Message stability

29 Cells from an amniocentesis can be used for DNA sequence analysis. All of the genes for humans will be known. Disease genes would be detected. Cloned “correct” genes could be used for replacement. Corrected nucleus could be delivered to an unfertilized egg. Same baby without the defect. Can humans be cloned and/or genetically engineered?

30 Could we Genetically Engineer Humans?

31 The Tay Sachs Dilemma

32 Do You Think We Should We Genetically Engineer Humans? (A) yes (B) no (C) depends on the circumstance

33 Issues in Biotechnology I would clone myself if that were possible. (A) yes (B) no (C) undecided

34 The Possibilities of Human Cloning

35 To Clone or Not to Clone

36 For those who are interested in taking this course for college credit through the University of Rhode Island; For those who are interested in taking this course for college credit through the University of Rhode Island; For more information please contact:

37 Credits Credits Lectures by: Edited by: Video Produced by: Thank You to The University of Rhode Island Thank You to The University of Rhode Island and all of the students of Issues in and all of the students of Issues in Biotechnology over the years Biotechnology over the years Dr. Albert Kausch and Kimberly Nelson Thaddeus Weaver


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