Presentation on theme: "OPERATIONAL RESEARCH What is it ? Why is it relevant ? Dr. Rony Zachariah MD, PhD Operational Centre Brussels MSF- Luxembourg"— Presentation transcript:
OPERATIONAL RESEARCH What is it ? Why is it relevant ? Dr. Rony Zachariah MD, PhD Operational Centre Brussels MSF- Luxembourg
Operational research: historical roots Military & industrial modelling defined as “the application of analytic methods to help make better decisions” Example: Military sector: anti-aircraft artillary efficiency
Examples: Commercial sector: Englands « Penny Post » – 1840 Efficient scheduling of airline crews
“What” is operational research Search for knowledge on interventions, strategies or tools that can enhance the quality, or coverage of health systems and services.
What is not operational research: Basic science research Randomised controlled trials [RCT] – where research is conducted in a strictly controlled environment, with inclusion and exclusion criteria – efficacy is the end point
The need for RCT and operational research: a necessary continuum RCT Patients and communities Generates knowledge (Trial conditions) Operational research ‘How to’ apply that knowledge ? (Real world conditions) Benefits +
Excellent evidence but gaps in implementation!
Malaria Kills 1 to 2 million people each year,
39% reduction in deaths
Why is operational research relevant ? Bridging implementation gaps
MALAWI Early 2000’s Population : 10 Million HIV/AIDS : 1 Million
Photo with permission 100,000 deaths/ year - no access to antiretroviral treatment
Malawi ,000 on ART
Measuring population Impact of ART on deaths “Coffin sales”
10,000 Deaths Averted ! Coffin sales in trouble
BURUNDI – Maternal Deaths Burundi 800 /100,000 Luxembourg 2 /100,000 MDG 5 Reduce deaths by 75% (2015) African countries – unlikely to achieve MDG 5
Reduced maternal deaths by 74%
Impact in relation to MDG 5 Reduction in maternal mortality ratio = 74%
40 low-income countries implementing five interventions – up to 27 years after ! Malaria Vaccinations
CONCLUSION Many years pass between ‘definitive’ trial results and policy and practice changeMany years pass between ‘definitive’ trial results and policy and practice change EU Research investmentEU Research investment 55.8 Billion Euros ( ) 55.8 Billion Euros ( ) –Technology/ Drugs/ Clinical trials Support operational research apply knowledge for maximum public benefit.Support operational research apply knowledge for maximum public benefit.