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Liver Functions Part II 3E1 From where we left off…

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Presentation on theme: "Liver Functions Part II 3E1 From where we left off…"— Presentation transcript:

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2 Liver Functions Part II 3E1

3 From where we left off…

4 In the small intestines Complete digestion occurs in the small intestines End products (glucose, amino acids, fatty acids, glycerol) diffuse into the blood vessels lining the small intestines. This process is called Absorption.

5 Some animal samples Guess what is the organ shown! From which animal?

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7 Adaptation of the small intestine for absorption

8 Structure of small intestine

9 What do you see in the intestinal walls?

10 How do the folds and villi help in absorption? The presence of folds and villi in the intestinal wall increase surface area

11 More adaptations from the small intestine the epithelial cell of the intestinal wall surface areaOne-celled thick epithelial wall and microvilli further increases surface area

12 The small intestines What makes the small intestines suitable for Absorption? 1) Elongated ileum, Inner surface of the ileum is folded These features provide large surface area:vol for absorption 2) Villi and microvilli

13 The small intestines What makes the small intestines suitable for Absorption? 3) Many blood vessels lining the small intestines

14 Absorption Absorption occurs by: –Diffusion –Active transport After absorption, Glucose and amino acids enter the blood capilliaries Glycerol and fatty acids enter the lacteals

15 How does absorption takes place in the intestines Absorption of fatty acids and glycerol Glycerol and fatty acids diffuse into the epithelium where they combined to form minute fat globules and enters the lacteals Fat globules mix with lymph in the lacteals to form chyle Liver is not involved *

16 Assimilation and function of the liver

17 Overview Role of DigestionMouth & Oesophagus Gall Bladder &Pancreas Stomach Large Intestine & Others Small Intestine

18 Overview – 4 Stages IngestionDigestion AbsorptionAssimilation

19 Lesson objectives: Describe the fate of glucose, amino acids and fats in the blood that leaves the intestines, after a meal. Describe the 5 major roles that the liver plays in the human body –Regulation of blood glucose concentration –Deamination of amino acids –Production of bile –Detoxication –Iron storage

20 Fate of glucose and amino acids

21 Transport and utilization of absorbed foods In the Liver! Types of absorbed food products Glucose Amino acids Fats

22 From the small intestines to the liver! How?? Connected by a vein called Hepatic Portal Vein!

23 Guess which part the vein connects to the intestine? A B C D

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25 Carbohydrate metabolism Hepatic portal vein transports sugars like glucose from the intestines to the liver

26 Question! Receives 5 glucose molecules from the intestines Requires only 3 glucose molecules for breathing

27 how many molecules of glucose do you think the liver would transport to the lungs? Receives 5 glucose molecules from the intestines Requires only 3 glucose molecules for breathing

28 Liver in Glucose metabolism Hepatic portal vein

29 In the liver…. 1. Some glucose carried in the blood to be distributed to the rest of the body -Tissue respiration Carbohydrate metabolism

30 In the liver…. - Glucose (excess) Glycogen (stored) Hormone : Insulin -If the glucose level is too low in the blood Glycogen (stored) Glucose Hormone: Glucagon Insulin and glucagon

31 What about the amino acids absorbed by the small intestines? Similar route as sugars: Intestines hepatic portal vein liver general blood circulation

32 Liver in Protein metabolism Hepatic portal vein

33 Fate of amino acids Amino acid metabolism Converted into protoplasm Used for growth & repair of worn- out parts Formation of enzymes & hormones Excess amino acids cannot be stored : Deamination

34 Deamination N H H COH || O R | C | H Amino group Carbon residue Ammonia (toxic) Urea (non-toxic) glucose glycogen

35 Intestines lacteal lymphatic vessels blood rest of the body Fat metabolism Fate of Fats maintenance of cell membranes Production of hormones Excess fats stored in adipose tissues When glucose supply is low, fats will be oxidised in the liver to provide energy (Liver not involved)

36 Summary: 5 major roles that the liver plays –Regulation of blood glucose concentration –Deamination of amino acids –Iron storage –Production of bile –Detoxication

37 True/False Liver is part of the alimentary canal

38 True/False Carbohydrates are digested in the liver

39 True/False Excess amino acids are deaminated

40 True/False Fats are absorbed in the liver and transport to other parts of the body for usage.


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