Presentation on theme: "Facial contour corrections with calcium hydroxyapatite granules and fibrin sealant Maurice Mommaerts President European Association for Cranio-Maxillo-Facial."— Presentation transcript:
1Facial contour corrections with calcium hydroxyapatite granules and fibrin sealant Maurice MommaertsPresident European Association for Cranio-Maxillo-Facial SurgeryBruges, Belgium7th Asian Pacific Craniofacial conference, Taipeh, Taiwan
2Issues Contour irregularities in corrective osteotomies In chin osteotomyIn sagittal split osteotomy for mandibular advancement in skinny ladiesPost trauma & congenital defectsOrbital regionTemporal areasLocalized midfacial deficiency in clefts and craniofacial syndromesResidual asymmetries uncorrectable with osteotomiesMandibular border & lateral surface
4Combination Bone paste Human cancellous bone Hydroxyapatite Pro Osteon (Interpore Cross)Pro OsteonImplant500Fibrin glueTisseel/TissucolBlood clotTisseel clot
5Sealant Fibrin sealant (FS) Purified fibrinogen (a protein) Purified thrombin (an enzyme)derived from human bloodHuman blood factor XIIIAprotinin, derived from cows' lungsFactor XIII strengthens blood clots by forming cross-links between strands of fibrinAprotinin is a protein that inhibits the enzymesthat break down blood clots
6Sealant Fibrin sealant (FS) Hemostasis Sealing Closing effect As of 2003, all fibrin sealants usedare made from blood plasma takenfrom carefully screened donorsand rigorously tested to eliminatehepatitis viruses, HIV-1, and parvovirus.
7Calcium hydroxylapatite Granules (HA)A mineralNaturally occurring form of calcium apatiteCa5(PO4)3(OH70% of bone is made up of HAAbility to integrate in bone structures &support bone ingrowth,without breaking down or dissolving(i.e it is bioactive)