Presentation on theme: "Facial contour corrections with calcium hydroxyapatite granules and fibrin sealant Maurice Mommaerts President European Association for Cranio-Maxillo-Facial."— Presentation transcript:
1 Facial contour corrections with calcium hydroxyapatite granules and fibrin sealant Maurice MommaertsPresident European Association for Cranio-Maxillo-Facial SurgeryBruges, Belgium7th Asian Pacific Craniofacial conference, Taipeh, Taiwan
2 Issues Contour irregularities in corrective osteotomies In chin osteotomyIn sagittal split osteotomy for mandibular advancement in skinny ladiesPost trauma & congenital defectsOrbital regionTemporal areasLocalized midfacial deficiency in clefts and craniofacial syndromesResidual asymmetries uncorrectable with osteotomiesMandibular border & lateral surface
4 Combination Bone paste Human cancellous bone Hydroxyapatite Pro Osteon (Interpore Cross)Pro OsteonImplant500Fibrin glueTisseel/TissucolBlood clotTisseel clot
5 Sealant Fibrin sealant (FS) Purified fibrinogen (a protein) Purified thrombin (an enzyme)derived from human bloodHuman blood factor XIIIAprotinin, derived from cows' lungsFactor XIII strengthens blood clots by forming cross-links between strands of fibrinAprotinin is a protein that inhibits the enzymesthat break down blood clots
6 Sealant Fibrin sealant (FS) Hemostasis Sealing Closing effect As of 2003, all fibrin sealants usedare made from blood plasma takenfrom carefully screened donorsand rigorously tested to eliminatehepatitis viruses, HIV-1, and parvovirus.
7 Calcium hydroxylapatite Granules (HA)A mineralNaturally occurring form of calcium apatiteCa5(PO4)3(OH70% of bone is made up of HAAbility to integrate in bone structures &support bone ingrowth,without breaking down or dissolving(i.e it is bioactive)