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Floppy-valve syndrome, Barlow’s syndrome Excessive connective tissue in the mitral leaflet  elongating and thickening the valve Displacement of the mitral.

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Presentation on theme: "Floppy-valve syndrome, Barlow’s syndrome Excessive connective tissue in the mitral leaflet  elongating and thickening the valve Displacement of the mitral."— Presentation transcript:

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2 Floppy-valve syndrome, Barlow’s syndrome Excessive connective tissue in the mitral leaflet  elongating and thickening the valve Displacement of the mitral valve into the LA during systole

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4  Females > males  More common among years old  Body features that could be associated with MVP: ▪ Asthenic body habitus ▪ Low body weight or body mass index (BMI) ▪ Straight-back syndrome ▪ Scoliosis or kyphosis ▪ Pectus excavatum ▪ Hypermobility of the joints ▪ Arm span greater than height (which may be indicative of Marfan syndrome)

5 Midsystolic Click  Classic auscultatory feature of MVP  Elongated leaflet balloons into the left atrium during systole leaflet collapses into the atrium, producing a click  Or produced by sudden tensing of slack, elongated chordae tendinae

6 Midsystolic Click

7  Midsystolic click may be followed by a high- pitched mid- to late systolic murmur  Crescendo-decrescendo, often heard best at the apex  Prolapse of the mitral valve causes some regurgitation of blood into the left atrium

8  Occurrence of click and murmur vary according to position  In general, any maneuver that decreases the end- diastolic LV volume, increases the rate of ventricular contraction or decreases resistance to the LV ejection of blood causes MVP to occur earlier in systole (standing, valsalva maneuver)

9  Anxiety  Panic attacks  Arrythmias  Exercise intolerance  Palpitations  Atypical chest pain  Fatigue  Orthostasis  Syncope or presyncope  Neuropsychiatric symptoms

10  Fatigue  Dyspnea  Exercise intolerance  Orthopnea  Paroxysmal nocturnal dyspnea (PND)  Progressive signs of congestive heart failure (CHF)


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