MassHunter LC-MS/MS Quantitative Analysis Software Page 3 Sensitivity Selectivity Parent Ions Enter Collision Cell - Collide with Ar Gas and Dissociates Q1 is Parked Allowing Only Parent Ions of a Single m/z to Pass to the Collision Cell Q3 is Parked Passing Only Product Ions of a Single m/z to the Detector Ion Guide Transports +/- Ions to Q1 +/- Ions and Neutrals Formed in API Source API Source Detector Energy Triple Quadrupole: MRM means “SIM”
MassHunter LC-MS/MS Quantitative Analysis Software Page 4 Pipeline software subsystem architecture Deliverables: Acquisition deliverables organized as Sequence table Acquisition Analysis Reporting Deliverables: Reporting results including graphics and calculations Deliverables: Reporting subsystem formats results and imports graphics
MassHunter LC-MS/MS Quantitative Analysis Software Page 6 MassHunter Quantitative Analysis Software Video Organization Batch-at-a-Glance Excel-base Reporting Method Editor Powerful sample and compound data visualization capabilities Flexible and customizable solution based on XML-mapping Create and edit an MRM method in a simple stepwise scenario 1. 2. 3.